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Purpose: Most patients with lumbar disc herniations requiring surgery have concomitant back pain. The purpose of the current study was to evaluate the outcome of surgery for lumbar disc herniations in patients with no preoperative back pain (NBP) compared to those reporting low back pain (LBP). Methods: 15,418 patients surgically treated due to LDH with primary discectomy from 1998 until 2020 were
BACKGROUND: When evaluating speech in children with cleft palate with or without cleft lip (CP/L), children with known syndromes and/or additional malformations (CP/L+) are usually excluded. The aim of this study was to present speech outcome of a consecutive series of 5-year-olds born with CP/L, and to compare speech results of children with CP/L + and children with CP/L without known syndromes a
Background: Obesity is a major public health problem of our time as a risk factor for cardiometabolic disease and the available pharmacological tools needed to tackle the obesity pandemic are insufficient. Neurotensin (NTS) is a 13 amino acid peptide, which is derived from a larger precursor hormone called proneurotensin or Long Form NTS (LF NTS). NTS modulates neuro-transmitter release in the cen
In order to meet the increasing needs of housing and services in urban areas, cities are densified. When densifying a city, it is important to provide good living conditions while maintaining a low environmental impact. To ensure this, the urban planning process should include simulations of e.g. noise and daylight conditions. In this paper we describe a newly started projected directed towards th
Background: The occupational risk of COVID-19 may be different in the first versus second epidemic wave. Aim: To study whether employees in occupations that typically entail close contact with others were at higher risk of SARS-CoV-2 infection and COVID-19-related hospitalisation during the first and second epidemic wave before and after 18 July 2020, in Norway. Methods: We included individuals in
Fire has substantially altered the course of human evolution. Cooking kindled brain expansion through improved energy and time budgets. However, little is known about the origins of fire use and its cognitive underpinnings (pyrocognition). Debates on how hominins innovated cooking focus on archaeological findings, but should also be informed by the response of animals towards heat sources. Here, w
Although there has been extensive research on pharmaceutical industry payments to healthcare professionals, healthcare organisations with key roles in health systems have received little attention. We seek to contribute to addressing this gap in research by examining drug company payments to General Practices in England in 2015. We combine a publicly available payments database managed by the phar
The Metadata 2020 initiative is an ongoing effort to bring various scholarly communications stakeholder groups together to promote principles and standards of practice to improve the quality of metadata. To understand the perspectives and practices regarding metadata of the main stakeholder groups (librarians, publishers, researchers, and repository managers), we conducted a survey during summer 2
Real-time fault monitoring and control of the Vacuum Assisted Resin Transfer Moulding production process requires knowledge of the position of the epoxy flow-front inside the mould. Therefore, a fast and accurate flow-front tracking system is highly prized. Physics-informed grey-box models deliver a good trade-off between high fidelity and data-driven black-box models for designing such a flow-fro
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency and resultant hyperglycemia. Complex interactions of genetic and environmental factors trigger the onset of autoimmune mechanisms responsible for development of autoimmunity to β cell antigens and subsequent development of T1D. A potential role of virus infections has long been hypothesized, and growing evide
The present study reports on the development of a questionnaire that evaluates children's experiences of their physical classroom environment, activities and interactions. It also explores the psychometric properties of the questionnaire and how acoustical characteristics of the classroom, class size and student characteristics (age, sex and Swedish as a second language) influence the self-reporte
Purpose: Vocabulary relates to overall language proficiency and is important for academic success. Word definition (WD) tasks can be used to assess vocabulary depth and definition skills. We investigate monolingual and bilingual children's performances on a WD task, and how bilingualism, level of parental education, school characteristics (proportion of students with Swedish as second language and
Purpose: We present the first nationwide study on endovascular therapy for basilar artery occlusion (BAO) from early hospital management to 3-month outcome. Methods: Data were collected on all acute ischaemic stroke patients registered 2016–2019 in the two national quality registers for stroke care and endovascular therapy (EVT), receiving EVT for BAO and subclassified into proximal, middle and di
We demonstrate that finite impulse response (FIR) models can be applied to analyze the time evolution of an epidemic with its impact on deaths and healthcare strain. Using time series data for COVID-19-related cases, ICU admissions and deaths from Sweden, the FIR model gives a consistent epidemiological trajectory for a simple delta filter function. This results in a consistent scaling between the
