Urinary incontinence affects 25–45 % of women with the gold standard surgical approach being placement of mid-urethral synthetic slings; tension-free vaginal tape (TVT) and trans-obturator tape (TOT). Due to the controversies regarding vaginal mesh the last decade, an increasing demand has evolved for incontinence treatment without vaginal synthetic mesh. The short term results of autologous rectu

The present work describes the formation of low-aspect-ratio Ag nanoparticles (NPs) arrays by sequential deposition of Ag from different growth directions on a nanoripple-patterned Si substrate, produced by low-energy ion beam irradiation. It is observed that the growth of Ag-NPs on ripple surfaces is direction-dependent due to the asymmetric ridge of the ripple pattern. This asymmetric ridge can

Background and Objectives: The role of body mass index (BMI) in Parkinson disease (PD) is unclear. Based on the Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in PD (Courage-PD) consortium, we used 2-sample Mendelian randomization (MR) to replicate a previously reported inverse association of genetically predicted BMI with PD and investigated whether findings were robus

Ras homolog gene family member C (RhoC) is a GTPase involved in cell migration, implicated in epithelial-mesenchymal transition and treatment resistance and metastasis of cancer. For example, RhoC has been shown to be involved in resistance to radiation in cervical carcinoma. Here, the effect of X-ray irradiation on RhoC expression in prostate cancer (PCa) xenografts was investigated in both xenog

We report the spectroscopic confirmation and fundamental properties of TOI−757 b, a mini−Neptune on a 17.5−d orbit transiting a bright star (V = 9.7 mag) discovered by the TESS mission. We acquired high−precision radial velocity measurements with the HARPS, ESPRESSO, and PFS spectrographs to confirm the planet detection and determine its mass. We also acquired space−borne transit photometry with t

We chart and assess the scope and utilisation of government-provided hospital infrastructure in British Africa, c. 1900-1960. Using various archival sources, we examine the heterogeneity in colonial administrations’ investment into curative healthcare provision across various regions of British Africa. Our research highlights significant disparities in healthcare provision during the colonial peri

Aim of the study: To assess the association of prevalence and size of pelvic sentinel node (SLN) metastases with risk factors in endometrial cancer (EC). Patients and Methods: Between June 2014 and January 2024 consecutive women with a uterine confined EC undergoing robotic surgery including detection of pelvic SLNs at a University Hospital were included. An anatomically based algorithm utilizing

Objective: Real-life management of hypertensive patients with chronic kidney disease (CKD) is unclear. Methods: A survey was conducted in 2023 by the European Society of Hypertension (ESH) to assess management of CKD patients referred to ESH-Hypertension Excellence Centres (ESH-ECs) at first referral visit. The questionnaire contained 64 questions with which ESH-ECs representatives were asked to e

A method is presented to reconstruct charged particles with lifetimes between 10ps and 10ns, which considers a combination of their decay products and the partial tracks created by the initial charged particle. Using the Ξ- baryon as a benchmark, the method is demonstrated with simulated events and proton-proton collision data at s=13TeV, corresponding to an integrated luminosity of 2.0fb-1 collec

Background: Neuroendocrine tumours (NETs) typically overexpress somatostatin receptors. By radiolabelling somatostatin analogues with a positron-emitting radionuclide (68Ga-DOTATOC or 68Ga-DOTATATE), these tumours can be detected with high sensitivity and specificity using somatostatin receptor positron emission tomography-computed tomography (PET-CT).Aim: To enhance knowledge about NETs imaged wi

Purpose: Different imaging tools, including digital breast tomosynthesis (DBT), are frequently used for evaluating tumor response during neoadjuvant chemotherapy (NACT). This study aimed to explore whether using artificial intelligence (AI) for serial DBT acquisitions during NACT for breast cancer can predict pathological complete response (pCR) after completion of NACT. Methods: A total of 149 wo

Objective: Targeted Health Dialogues (THD) is a public health intervention program that aims at preventing cardiovascular disease. THDs were implemented in the Swedish region Scania, in 2020, with the novelty of being conducted in a metropolitan area with a multiethnic population. This study investigated the prevalence of obesity among 40-year-old THD participants in Scania by region of birth, and

This study aims to determine the optimal pressure for the accumulator tank in a wave energy converter (WEC) with hydraulic power take-off (PTO) to maximize energy generation. A simulation-based approach was employed to analyze the buoy's performance with wave data generated from the Wafo toolbox using the generalized Pierson–Moskowitz (GPM) spectrum. These data were then fed into a Simulink model

Hydrological models are generally calibrated and validated using a suite of well-known statistical metrics, which sometimes lack clear connection and tailoring to the local users’ need and therefore limits the evaluation, especially in the case of global climate services. Therefore, in this study, two types of application-based evaluation metrics are introduced, addressing (i) temporal matching of