Cell therapy raises hopes high for better treatment of brain disorders. However, the majority of transplanted cells often die soon after transplantation, and those that survive initially continue to die in the subacute phase, diminishing the impact of transplantations. In this study, we genetically modified transplanted human neural stem cells (hNSCs), from 2 distant embryonic stem cell lines (H9

Background: Mental illness is one of the fastest rising threats to public health, of which depression and anxiety disorders are increasing the most. Research shows that diet is associated with depressive symptoms or depression (depression). Aim: This study aimed to investigate the diets impact on depression, by reviewing the scientific evidence for prevention and treatment interventions. Method: A

Purpose: The purpose of this document is threefold: (a) review the uses of the terms “vocal fatigue,” “vocal effort,” “vocal load,” and “vocal loading” (as found in the literature) in order to track the occurrence and the related evolution of research; (b) present a “linguistically modeled” definition of the same from the review of literature on the terms; and (c) propose conceptualized definition

Based on the multiphase field conception and integrated with the idea of vector valued phase fields, a phase field model for typical allotropic transformation of solid solution is proposed. The model takes the non-uniform distribution of grain boundaries of the parent phase and the crystal orientation into account, as illustrated in simulations of austenite to ferrite transformation in low carbon Based on multiphase field conception and integrated with the idea of vectorvalued phase field, a phase field model for typical allotropic transformation of solid solution is proposed. The model takes the non-uniform distribution of grain boundaries of parent phase and crystal orientation into account in proper way, as being illustrated by the simulation of austenite to ferrite transformation in lo

In this study, I investigate what a figurative sense is in the Swedish Academy Dictionary (SAOB). The description of figurative senses in the dictionary is analyzed in terms of word classes and the use of specific labels in the definitions, such as bildl. (figurative), is mapped out. From a cognitive semantic perspective, I investigate what the figurative uses of the present cases consist of, in a

We present spectroscopic determinations of the effective temperatures, surface gravities, and metallicities for 21 M dwarfs observed at high resolution (R ∼ 22,500) in the H band as part of the Sloan Digital Sky Survey (SDSS)-IV Apache Point Observatory Galactic Evolution Experiment (APOGEE) survey. The atmospheric parameters and metallicities are derived from spectral syntheses with 1D LTE plane-

Background: If individual differences are relevant and prominent features of personality, then they are expected to be encoded in natural language, thus manifesting themselves in single words. Recently, the quantification of text data using advanced natural language processing techniques offers innovative opportunities to map people’s own words and narratives to their responses to self-reports. He

In this study, we provide the results of radiological characterization of the RBMK-1500 graphite using modeling and nuclear spectrometry; we also introduce a method to identify neutron activation and surface contamination terms for the spent graphite waste. The simplified model of the reactor core created by programme package SCALE 6.2 for 4 × 4 fragment of the core was used for simulation of neut

Background: Microbial communities in human milk and those in feces from breastfed infants vary within and across populations. However, few researchers have conducted cross-cultural comparisons between populations, and little is known about whether certain “core” taxa occur normally within or between populations and whether variation in milk microbiome is related to variation in infant fecal microb

Over the past two decades, there has been a sharp rise in the use of prescription opioids. In several countries, most notably the United States, opioid-related harm has been deemed a public health crisis. As surgeons are among the most prolific prescribers of opioids, growing attention is now being paid to the role that opioids play in surgical care. While opioids may sometimes be necessary to pro

Background: KIT mutations are the predominant driver mutations in gastrointestinal stromal tumors (GISTs), and targeted therapy against KIT has improved treatment outcome dramatically. However, gaining secondary mutation of KIT confers drug resistance of GISTs leading to treatment failure. Results: In this study, we found that secondary mutation of KIT dramatically increases the ligand-independent

Coronautbrottet är ett hot mot Sveriges nationella säkerhet. Det riskerar leda till en ökning av främmande makters aktiviteter, terrorattacker, organiserad brottslighet samt social oro, skriver Ardavan Khoshnood, specialistläkare, kriminolog och statsvetare.The corona eruption is a threat to Sweden's national security. It risks leading to an increase in the activities of foreign powers, terrorist attacks, organized crime and social unrest, writes Ardavan Khoshnood, specialist physician, criminologist and political scientist.