Genom att öka handlingsutrymmet för medarbetarna i kärnuppdraget kan offentlig sektor bli mer effektiv och serviceinriktad. Grunden är en styrning som präglas av tillit och lyhördhet. Tillit är nödvändigt för att vårt samhälle ska stå starkt och för att statliga myndigheter, kommuner och regioner ska lyckas med sina uppdrag. Men hur bygger vi tilliten?I den här boken får du en introduktion till hu

OBJECTIVE: To investigate the influence of intravenous (iv) fluid volumes on the secretion of N-terminal-pro-brain natriuretic peptide (NT-Pro-BNP) in colorectal surgical patients and its association with cardiopulmonary complications (CPC). In addition, to examine if preoperative NT-Pro-BNP can predict the risk for postoperative CPC. METHODS: Blood samples from patients enrolled in a previously p

Background Implementation in healthcare is often slow and poorly reported. Results include suboptimal outcomes and ad-verse consequences for patients. However, promising tools to remedy implementation speed and reporting already exist – such as the evidence-based, fast-track implementation model (Fast-IM) and the comprehensive RE-AIM (reach, effectiveness, adoption, implementation, and maintenance

Inom Svenska kyrkan talas idag ofta om vikten av att rekrytera ideella medarbetare. I en tid då de ekonomiska resurserna minskar blir det viktigt att på nytt arbeta med människors engagemang. Vi har vant oss vid att de anställda medarbetarna är många, men hur och varför växte de stora arbetslagen fram?Detta är en bok om hur lekmannamedarbetare kom att bli en naturlig del av den församlingsverksamh

Background: Infertile men with non-obstructive azoospermia (NOA) have impaired spermatogenesis. Dilated and un-dilated atrophic seminiferous tubules are often present in the testes of these patients, with the highest likelihood of active spermatogenesis in the dilated tubules. Little is known about the un-dilated tubules, which in NOA patients constitute the majority. To advance therapeutic strate

Background: Urinary retention is common in elderly patients undergoing acute hip fracture surgery. Avoiding overfilling the urinary bladder is important to avoid detrusor muscle damage and associated motility problems. The aim of this study was to analyse associations between the co-creation of a nurse-driven urinary catheterisation protocol and the incidence of bladder distension in patients unde

This book, based on extensive original research, examines the practice by women in a university sport setting of kendo, the Japanese martial art which, using bamboo swords as well as protective armour, and descended from traditional swordsmanship, instils in its practitioners, besides physical skills, societal values of etiquette and resilience as well connecting them to a "traditional" outlook, w

Variability on centennial to multi-centennial timescales is mentioned as a feature in reconstructions of the Holocene climate. As more long transient model simulations with complex climate models become available and efforts have been made to compile large proxy databases, there is now a unique opportunity to study multi-centennial variability with greater detail and a large amount of data than ea

The nucleolar surveillance pathway monitors nucleolar integrity and responds to nucleolar stress by mediating binding of ribosomal proteins to MDM2, resulting in p53 accumulation. Inappropriate pathway activation is implicated in the pathogenesis of ribosomopathies, while drugs selectively activating the pathway are in trials for cancer. Despite this, the molecular mechanism(s) regulating this pro

Objective To determine if plasma transfusions with male donor plasma to very preterm infants affect circulatory levels of sex steroids. Design and patients Retrospective multicentre cohort study in 19 infants born at gestational age

Background: Heart failure (HF) has been associated with psychosocial distress, but other long-term mental health sequelae are unclear. Objectives: In this study, the authors sought to determine risks of major depression and suicide, susceptible time periods, and sex-specific differences after HF diagnosis in a large population-based cohort. Methods: A national cohort study was conducted of all 154

This is a cartographic vertical analysis of a verdict by the Swedish Supreme Administrative Court, regarding the right to support from the Social Services (HFD 2017 ref. 33). The case concerned three children and their mother whom lacked formal residency. They applied for assistance under the Social Services Act and the municipality’s health and welfare committee rejected the application. Followin

Many animal behaviors require orientation and steering with respect to the environment. For insects, a key brain area involved in spatial orientation and navigation is the central complex. Activity in this neural circuit has been shown to track the insect’s current heading relative to its environment and has also been proposed to be the substrate of path inte-gration. However, it remains unclear h

aim: Approximately one in five patients with acute diverticulitis (AD) will experience a recurrence. This study aimed to investigate the factors at AD admission that correlate with recurrence and test the proposed risk of recurrence-score according to Sallinen et al. method: This retrospective study followed patients for five years who were admitted with operatively or computed tomography (CT)veri

Objective. This study proposes a novel technique for atrial fibrillatory waves (f-waves) extraction and investigates the performance of the proposed method comparing with different f-wave extraction methods. Approach. We propose a novel technique combining a periodic component analysis (PiCA) and echo state network (ESN) for f-waves extraction, denoted PiCA-ESN. PiCA-ESN benefits from the advantag

Selective serotonin reuptake inhibitors (SSRIs) and internet-based cognitive behavioral therapy (ICBT) are recommended treatments of social anxiety disorder (SAD), and often combined, but their effects on monoaminergic signaling are not well understood. In this multi-tracer positron emission tomography (PET) study, 24 patients with SAD were randomized to treatment with escitalopram+ICBT or placebo

Objective To estimate the incidence of acute mesenteric ischaemia (AMI), proportions of its different forms and short-term and long-term mortality. Design Systematic review and meta-analysis. Data sources MEDLINE (Ovid), Web of Science, Scopus and Cochrane Library were searched until 26 July 2022. Eligibility criteria Studies reporting data on the incidence and outcomes of AMI in adult populations

Background: Unfractionated heparin (UFH) is frequently administered before percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). Aims: The aim of the study was to investigate if pretreatment with UFH prior to arrival at the catheterisation laboratory affects coronary artery occlusion, mortality, and in-hospital major bleeding in patients with