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Neurophysiological Treatment Effects of Mesdopetam, Pimavanserin and Amantadine in a Rodent Model of Levodopa-Induced Dyskinesia

Levodopa provides effective symptomatic treatment for Parkinson's disease. However, nonmotor symptoms are often insufficiently relieved, and its long-term use is complicated by motor fluctuations and dyskinesia. To clarify mechanisms of levodopa-induced dyskinesia and pharmacological interventions aimed at reducing dyskinetic symptoms, we have here characterized the neurophysiological activity pat

Ice core dating with the 36Cl/10Be ratio

Extremely thinned layers and possible folding make the dating of the deepest sections of ice cores especially challenging. Cosmogenic radionuclides have the potential to provide independent age estimates. The 36Cl/10Be ratio is largely independent of production rate changes that affect individual radionuclides and has an effective half-life of 384 kyr, making it an ideal tool for dating the new 1.

Community Perceptions and Preferences of Cash Assistance in Disaster Contexts in Nepal

This thesis explores how disaster-affected communities in the Kavre and Bardiya districts of Nepal perceive and experience cash assistance projects. The research was guided by two core questions: (1) What are community members' perceptions and preferences of cash assistance in disaster affected areas in the Kavre and Bardiya districts of Nepal? (2) How could these community perceptions and pre

Towards a Circular Future: A Roadmap for Sustainable Industrial Packaging

As global industries face increasing pressure to adopt circular economy principles and comply with sustainability regulations, packaging has emerged as an important strategic driver. This thesis explores the case of a global industrial manufacturer and how it can enhance its packaging innovation capabilities and align with upcoming regulatory frameworks, such as the Corporate Sustainability Re

Solvolysis-Driven Chemical Recycling of Wind Turbine Blade Waste

Grön energi, som vind-, sol- och vattenkraft, spelar en avgörande roll i omställningen från fossila bränslen. Men hur hållbara är dessa energikällor sett till hela livscykeln? Inom vindkraftsindustrin är detta en särskilt viktig fråga. Vindkraftsblad tas vanligtvis ur bruk efter 20–25 års drift, och har historiskt sett främst gått till förbränning eller deponi. Inget av alternativen är hållbara efThe growing accumulation of end-of-life wind turbine blades (WTBs) presents a challenge due to their increased usage around the world and complex composite structure. Mechanical and thermal recycling techniques often fail to completely recover both the matrix and the embedded fibers without significant degradation or environmental burden. In this thesis, solvolysis is investigated as a promising r

Enablers and Barriers of Digital Servitization of Sweden's SME

The increase in global competitiveness and the advancement of digital technology are compelling organizations to innovate by enhancing their product offerings with digital services. Although this phenomenon known as digital servitization is well researched in larger organizations, there is less investigation on how small and medium enterprises (SMEs) manage this trend, particularly in Sweden. This

Techno-Economic Evaluation of Lignocellulosic Bio-Oil Processes

Från industriella restprodukter till grönt drivmedel – två vägar mot förnybara bränslen. Bio-olja från skogsrester kräver uppgradering för att kunna behandlas i befintliga oljeraffinaderier. Två innovativa processer visar potential, men tekniska och ekonomiska utmaningar framstår. Att minska beroendet av fossila bränslen är avgörande för att nå klimatmålen. Ett lovande alternativ är att producerThis master’s thesis evaluates the commercial-scale feasibility of two processes that upgrade lignocellulosic bio-oil: dewatering and derivatization upgrading (DDU) and green cooking and cleaning (GCC). Both processes aim to produce upgraded bio-oil suitable for co-processing in existing oil refineries, though they differ significantly in complexity. GCC includes the entire conversion from raw bio

Revolutionizing Retail: The Role of Augmented Reality-Driven Information Systems in Enhancing Customer Experience and Engagement

Augmented reality (AR) is increasingly being adopted in fashion retail to enhance customer ex-perience, boost engagement, and reduce uncertainty in online shopping environments. While AR offers both hedonic and utilitarian value, its implementation across large multinational fashion companies remains inconsistent due to financial, technological, and organizational barriers. This study investigates

Recommender Systems for E-Commerce Platforms: towards a more sustainable consumption

This master’s thesis explores Recommender Systems (RS) and how these can promote sustainable consumption on e-commerce platforms by influencing consumer behaviour toward environmentally responsible choices. The aim is to provide design recommendations for sustainability-aware RS that align user preferences and environmental goals. Two research questions guided the study: how RS are designed to enc

Jämställdhet för konsulter inom byggbranschen

Titel: Jämställdhet för konsulter inom byggbranschen. Författare: Amanda Age och Ellen Ivarsson Handledare: Radhlinah Aulin Examinator: Anne Landin Syfte & mål: Syftet med examensarbetet är att undersöka och jämföra hur jämställdheten upplevs för konsulter inom byggbranschen i Sverige och Italien. Rapporten syftar till att identifiera faktorer som bidrar till en ojämställd arbetsmiljö samt förTitle: Equality for consultants within the construction industry Authors: Amanda Age och Ellen Ivarsson Supervisor: Radhlinah Aulin Examiner: Anne Landin Aim & goal: The purpose with this thesis is to study and compare how gender equality is perceived by consultants within the construction industry in Sweden and Italy. The thesis also aims to identify factors that contribute to an unequal wor

Artificial Intelligence and Creative Work in the Swedish Gaming Industry

The rapid emergence of generative artificial intelligence has sparked both excitement and concern across creative industries. The thesis examines how professionals in the Swedish gaming industry perceive Gen-AI’s role in creative workflows. Using a qualitative approach grounded in semi-structured interviews, an extended Technology Acceptance Model is ap-plied to explore themes such as usefulness,

Understanding ICT Use For Social Connectedness Among Older Adults

Social isolation and loneliness among older adults are growing public health concerns. Although information and communication technologies (ICT) are increasingly promoted to foster social connectedness, how older adults perceive and adopt these technologies remains underexplored. This study applies the Unified Theory of Acceptance and Use of Technology (UTAUT) to examine ICT engagement among older

Miljöbyggnad 4.0: Utmaningar & möjligheter för svenska byggprojekt - En analys av uppdateringarnas påverkan på hållbart byggande

Detta examensarbete undersöker hur de uppdaterade kriterierna i certifieringssystemet Miljöbyggnad påverkar hållbarhetsmålen inom bygg- och fastighetssektorn. Arbetet utgår från den centrala problematiken att byggsektorn är en av de största källorna till utsläpp och negativ miljöpåverkan. Miljöcertifieringssystem har potentialen att minska den negativa miljöpåverkan inom bygg- och fastighetssektorThis thesis examines how the updated criteria in the Miljöbyggnad certification system affect sustainability goals in the construction and real estate sector. The work is based on that the construction sector is one of the largest sources of emissions and negative environmental impact. Environmental assessment methods have the potential to reduce the negative environmental impact of the constructi

Implementing and Designing AI-Powered Chatbots: Organisational Perspectives on Data Quality, Key Drivers, and Barriers in Medium and Large Swedish Enterprises

Denna kandidatuppsats undersöker hur medelstora och stora svenska företag uppfattar datakvalitet vid design och implementering av AI-drivna chattbotar för internt bruk. Studien bygger på fem semistrukturerade intervjuer med yrkesverksamma som varit direkt involverade i utvecklingsarbetet och belyser hur organisationer ser på faktorer som datans noggrannhet, fullständighet och tillförlitlighet. ResThis bachelor’s thesis investigates how medium and large Swedish enterprises perceive data quality during the design and implementation of AI-powered chatbots for internal use. Through five semi-structured interviews with professionals directly involved in the chatbot development, the study explores organisational perspectives on data accuracy, completeness, and reliability, as well as key drivers

Digitala rekryteringsverktyg: En studie om hur AI och automatisering används och upplevs i rekryteringsprocessens tidiga skede

Digitaliseringen har omformat rekryteringsprocessen, där digitala verktyg som bygger på automatisering och artificiell intelligens (AI) fått en allt mer framträdande roll. Denna studie undersöker hur digitala rekryteringsverktyg används och upplevs av både yrkesverksamma och kandidater under rekryteringsprocessens tidiga skede. Genom kvalitativa intervjuer belyses användning, upplevelser och attit

Effektivare upphandlingsprocesser - En systemanalys av urvalsprocesser, kommunikation och uppföljning

This thesis presents a comprehensive systems analysis of the impact of quality assessments, communication practices, and monitoring mechanisms on the efficiency of public procure-ment in the Swedish construction sector. Recognizing that public procurement is a corner-stone for societal infrastructure and development, the study specifically examines procure-ment regulated by the Swedish Public Proc

Predicting Antibody Developability: Machine Learning Meets Therapeutic Antibodies

Antibody developability refers to an antibody’s suitability for clinical use, including properties such as solubility, stability, and aggregation. These traits are traditionally assessed through experimental screening, which is time-consuming and resource heavy. Machine learning offers a promising alternative for early prediction of developability, though many existing models are still in early st

LoVis4u : a locus visualization tool for comparative genomics and coverage profiles

Comparative genomic analysis often involves visualization of alignments of genomic loci. While several software tools are available for this task, ranging from Python and R libraries to stand-alone graphical user interfaces, a tool is lacking that offers fast, automated usage and the production of publication-ready vector images. Here we present LoVis4u, a command-line tool and Python API designed

Iberian Anarchism in Environmental History

In recent years, there has been a renewed interest in anarchism from both social movements and critical academic circles. When tracing the genealogy of anarchist perspectives since the nineteenth century, radical geographers have pointed out the importance of the anarchist movement in Spain, and particularly in the city of Barcelona. During the 1960s and 1970s, authors like Murray Bookchin shared