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Dosimetric verification of open asymmetric photon fields calculated with a treatment planning system based on dose-to-energy-fluence concepts
Output normalized dose profiles for asymmetric open photon fields has been calculated using a commercial treatment planning system (TPS) based on a dose-to-energy-fluence concept. The model does not require any additional measurements for off-axis fields. Calculations are compared with measurements for quadratic fields of 5 cm x 5 cm up to 20 cm x 20 cm, with their geometric field centre positione
Chromatin modification by lipids and lipoprotein components: an initiating event in atherogenesis?
Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors.
The finding that alkyl 1,4-dihydro-4-oxoquinoline-3-carboxylate and N-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxamide derivatives may be high-affinity ligands at the benzodiazepine binding site of the GABAA receptor, prompted a study of 3-acyl-1,4-dihydro-4-oxoquinoline (3-acyl-4-quinolones). In general, the affinity of the 3-acyl derivatives was found to be comparable with the 3-carboxylate and th
Standards of care for acute and chronic musculoskeletal pain: The bone and joint decade (2000-2010)
Musculoskeletal conditions often manifest with the onset of pain and the resulting physical limitations. Musculoskeletal pain is almost inevitable in in individual's lifetime. It is one of the most common reasons for self-medication and entry into the health care system. Musculoskeletal pain affects in 4 adults and is the Most commons Source of serious long-term pain and physical disability. The M
Helping alliance and early dropout from psychiatric out-patient care The influence of patient factors.
Background The study examined client factors of relevance in the establishment of helping alliance and in the prediction of dropout from a routine psychiatric setting admitting a variety of diagnoses and staffed with a multiprofessional team. Method Newly admitted patients (n=122) and staff completed questionnaires regarding helping alliance, and the patients also completed questionnaires regardin
Riks-stroke - a Swedish national quality register for stroke care
BACKGROUND: Riks-Stroke, the Swedish national quality register on stroke care, provides unique opportunities to evaluate stroke units in routine clinical care. METHODS: Basic patient characteristics, process indicators and outcome variables are recorded in all 85 hospitals admitting acute stroke patients. A 3-month follow-up is included. RESULTS: There are wide variations between hospitals in the
Dissecting karyotypic patterns in malignant melanomas: Temporal clustering of losses and gains in melanoma karyotypic evolution.
The effect of exercise on the absorption of inhaled human insulin in healthy volunteers
What is already known about this subject * Exercise is known to affect absorption of other inhaled substances, but so far there are no reports on the effect of exercise on the absorption of inhaled insulin in humans. What this paper adds * This report is the first to investigate the effect of exercise on the absorption of inhaled insulin. * In this study in healthy volunteers we found that exercis
Can we reduce the burden of musculoskeletal conditions? The European action towards better musculoskeletal health
Clean the Air, Heat the Planet?
Temperature, genetic and hydroperiod effects on metamorphosis of brown frogs Rana arvalis and R-temporaria in the field
Time for metamorphosis and metamorph size of moor frogs Rana arvalis and common frogs R. temporaria were measured in 22 ponds for 18 years. Environmental data in these ponds were also measured. Metamorphosis of the frogs took place from the beginning of June to the beginning of August. When both species were found in one pond, the common frogs metamorphosed up to 20 days earlier than the moor frog
Total hydrocarbon flux dynamics at a subarctic mire in northern Sweden
This is a study of the spatial and temporal variability of total hydrocarbon (THC) emissions from vegetation and soil at a subarctic mire, northern Sweden. THCs include methane (CH4) and nonmethane volatile organic compounds (NMVOCs), both of which are atmospherically important trace gases and constitute a significant proportion of the carbon exchange between biosphere and atmosphere. Reliable cha
Metabolic consequences of hard work
When an animal has to meet increased demands on its working capacity, for example, for thermoregulation or parental care, two strategies are available. The animal can reallocate energy from costly maintenance processes-such as immunological defence or DNA repair systems (compensation hypothesis)-or it may try to increase the rate of energy intake or efficiency of digestion by increasing the size o
Mouse models for rheumatoid arthritis
Rheumatoid arthritis (RA) affects millions of people world wide causing considerable human suffering and large socioeconomic costs. Increased knowledge of pathological pathways involved in RA will enable development of modern drugs, with reduced side effects. The mouse models offer an attractive approach to dissect the genetic and molecular mechanisms of RA.
Dissecting the PPP puzzle: the unconventional roles of nominal exchange rate and price adjustments
The conventional view, as expounded by sticky-price models, is that price adjustment determines the PPP reversion rate. This study examines the mechanism by which PPP deviations are corrected. Nominal exchange rate adjustment, not price adjustment, is shown to be the key engine governing the speed of PPP convergence. Moreover, nominal exchange rates are found to converge much more slowly than pric
Intracellular signaling pathway alterations in laminin alpha 2 chain deficient skeletal muscle and brain
Recombinant factor VIIa (rFVIIa): its potential role as a hemostatic agent
Recombinant activated coagulation factor VII (rFVIIa) was developed for the treatment of patients with hemophilia who have developed inhibitors against the factor they are missing. Hemophilia is a serious bleeding disorder and patients with hemophilia develop repeated spontaneous CNS, joint and muscle bleeding. Any trauma, even mild events, may cause life-threatening bleeding, and without treatmen
Genetic Diversity Patterns in Five Protist Species Occurring in Lakes.
Little is known about the extent of the genetic diversity and its structuring patterns in protist species living in lakes. Here, we have investigated the genetic diversity patterns within five dinoflagellate species (Peridinium aciculiferum, Peridinium cinctum, Peridiniopsis borgei, Polarella glacialis, Scrippsiella aff. hangoei) that are present in lakes and sometimes, in marine habitats located
Delayed healing after CO2 laser resurfacing.
Skin resurfacing with carbon dioxide (CO2) laser is a currently popular means of improving rhytides and scars of the face. Side effects are few, but delayed healing has been reported due to infections. A case of unexplained slow healing following CO2 laser resurfacing in a previously healthy sixty-seven year old woman is reported. Although healing was extremely delayed, it is important to emphasiz