Single chain fragment variable (scFv) antibodies from the library Hel11 are used in microarray applications for biomarker discovery. However, some scFv antibodies have been difficult to produce at sufficient yields and purity levels. In order to optimize the production of problematic scFv antibodies, three Hel11 scFv antibodies (PC244, PC253, and PC274) were chosen and the impact of the following

This paper presents a comparison of ranking between two different performance measures, Sharpe Ratio and Certainty Equivalent Returns, on U.S. tech sector funds. Firstly, we compared the ranking of funds based on the Sharpe Ratio family, i.e. the traditional Sharpe Ratio, Reward-to-VaR and Reward-to-ES. The strong correlation between the rankings is in line with the previous studies. Further, by c

I dagens I-länder är neurologiska sjukdomar en av de främsta orsakerna bakom dödsfall. Enligt statistik från ”Disabled World” påverkas upp till 1 miljard människor världen över av någon form av neurologisk sjukdom, vilket inkluderar allt från epilepsi och migrän till Alzheimer och stroke. Till följd av detta är medicin för att såväl förhindra som att motverka skador från neurologiska sjukdomar enAQP4 is a protein in the brain which regulate the diffusion of water in and out of cells. Through studies using AQP4 null mice, a correlation between the regulation of AQP4 and the survival rate of cerebral edemas has been noted. Due to the fact that there are three different kinds of cerebral edemas, and that they require different kinds of regulation of AQP4 in order to lessen the problem, the r

Studien ämnade att undersöka huruvida det går att predicera kreativitet utifrån variablerna typ av regulatory focus, typ av motivation och öppenhet för erfarenhet då kreativitet som egenskap kan vara problematisk att mäta. Syftet med undersökningen var att företag ska kunna använda denna kunskap vid rekryteringar, bemötande av personal och samarbetsfrågor. För detta syfte använde studien sig av reThe study aimed to explain whether it is possible to predict Creativity based on the variables Regulatory Focus style, Motivation style and Openness for Experience since the trait creativity can be troublesome to measure. The ambition was that companies will find this information useful when recruiting new co-workers, handling employees and when dealing with cooperation matters. To serve this purp

This thesis investigates the influence of personality, preference for working in virtual teams, alone or in face-to-face teams on work motivation and team climate of individuals working in virtual teams. This study used mixed methods, by collecting experiences of virtual team members in regard to inhibitors and success factors of their team and data from personality and motivational scales. The re

This paper stems from understanding how fast fashion retailers market their sustainability and how the retail space drives different forms of sustainable performances and consumption. Departing from a practice-based approach and practice theory, the study gives insights on how retailers actions in the production chain are translated in-store and online for consumers sense-making, performances and

The aim of this study was to examine what factors ex-offenders consider has facilitate and prevent their turning points for leaving a criminal life. In addition, the purpose was also to investigate how ex-offenders experienced prison as a factor for re-entry in society. From those two perspectives of view we also wanted to ascertain if prison or factors that are non-legal are the most successful f

Syftet med denna studie är att undersöka de attityder, hinder och möjligheter som yrkesarbetare och platsledning ser i och med yrkesarbetares användande av mobiltelefoner i den dagliga verksamheten. Målet är att resultatet ska bidra till förståelse för de svårigheter och barriärer som kan uppkomma vid implementering av digitala verktyg, att finna tillvägagångssätt för att minimera dessa samt för a

Den snabba utvecklingen av nya digitala verktyg leder till nya möjligheter för fjärrvärmebranschen inom områden som laststyrning och feldetektering. För dessa ändamål behövs tillförlitliga modeller som beskriver centralerna. Syftet med denna studie är att utveckla en grupp matematiska modeller som beskriver uppmätta värden och deras utveckling över tid, för en väl fungerande fjärrvärmecentral. FörIn the rise of digitalization, new possibilities are being discovered for district heating in areas like demand side management and fault detection. For these purposes it is necessary to have reliable models describing the substations. In this thesis, the aim is to develop a group of mathematical models to describe measured quantities and their progress through time, for a well performing substati

This thesis explores what it means to struggle for food sovereignty under belligerent occupation. It makes the argument that the deliberate suppression of agriculture in the West Bank (occupied Palestinian territories) and ensuing deterioration of food sovereignty can be understood as an example of “slow violence,” further entrenching the settler-colonial occupation of Palestine. The settler-colon

Understanding events’ impact on financial instruments are crucial for the participants in the financial markets. Here we propose an approach to model an anticipated event’s impact on the prices of FX options, represented in implied volatility. The model is implemented for anticipated event’s with both Black and Scholes and SABR as the assumed underlying dynamic. The model generates an implied vola

Globalization has led to the emergence of global value chains (GVCs) and most of the world’s trade is now in intermediate inputs. This has raised questions about employment in GVCs and attracted the interest of researchers and policymakers alike, but is difficult to study empirically. This paper investigates job creation in simple and complex GVCs for 43 economies between 2000 and 2014 on the basi

Att rättstillämpningen förutsätter en rätt är sällan ifrågasatt. Än mer sällan ifrågasätts vad denna rätt egentligen är: frågan framstår närmast naiv. Genom att utgå från bland annat deleuzeoguattaris kunskapsteoretiska utgångspunkter söker jag inleda en diskussion om rättens vara. Efter en kartläggning av och diskussion kring de deleuzeoguattariska spåren genom rättsvetenskapen idag genomför jag The fact that jurisdiction requires a juris is rarely questioned. All the more rare is the question of what the law really is: the question stands out as almost naïv. By putting into play the epistemological thought of philosophers such as Deleuzeoguattari I will try to initiate a discussion concerning the being of law. After a brief orientation in the dealings of jurisprudence with deleuzeoguatta

Det finns olika teorier kring vem som bevisbördan ska falla på inom tvistemål när det råder oenighet kring huruvida ett visst rättsfaktum ligger för handen. Bevissäkringsteorin är en av dessa. Bevissäkringsteorin innebär att bevisbördan läggs på den som har haft det lättast för att säkra bevisning. Mot bevissäkringsteorin konkurrerar de materiella bevisteorierna. Dessa teorier förespråkar att beviThere are different theories regarding who should carry the burden of proof within civil cases when there is controversy regarding whether or not a certain fact is at hand. The theory of securing evidence is one of these. The theory of securing evidence states that the burden of proof should be placed on whomever has an easier time of securing evidence. The material theories of evidence compete wi

Målet med examensarbetet är att korrelera en simuleringsmodell med ett fysiskt test av en Lynk & Co 01. Simuleringsmodellen är en komplett fordonssimulering som innefattar en simuleringsmodell i Adams och en simuleringsmodell i MSC Nastran. För att kunna utföra korrelationen är olika förkorrelationsfaser nödvändiga. Dessa faser består av att få en förståelse för simuleringsmodellen, utveckla vThe aim of the master thesis project is to correlate a simulation model with a physical test of the Lynk & Co 01. The simulation model is a complete vehicle simulation which includes an Adams simulation model and a MSC Nastran simulation model. To carry out the correlation, different pre-correlation phases are necessary. These phases consist of obtaining an understanding of the simulation mode

Purpose: With this study, an attempt was made to present an in-depth analysis of and study the interaction between PR agencies and their client’s CSR strategies in order to illuminate the contributions of public relations to these, and also to review current CSR activities applied in Serbia. Furthermore, the purpose was to foster the role of PR as an agent for change regarding CSR strategies. R

Given the recent changes in how central banks use the tools they have at hand to control inflation and money supply this study aims to evaluate the effect that interest rate policy has had on IPO underpricing. More specifically, the effect that negative interest rate policies and quantitative easing has had on the size of the underpricing premium. To test these effects, we collected IPO data from

Globalization has intensified interdependencies between countries, generating both winners and losers from trade in Global Value Chains. While economic theory predicts a net welfare gain from international trade on the aggregate level of an economy, geographical differences on the regional level and the need for territorial redistribution policies have been neglected, causing political backlashes.