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The main function of CAs (carbonic anhydrases) is to participate in the regulation of acid-base balance. Although 12 active isoenzymes of this family had already been described, analyses of genomic databases suggested that there still exists another isoenzyme, CA XV. Sequence analyses were performed to identify those species that are likely to have an active form of this enzyme. Eight species had
Abstract in UndeterminedBackground: The software development environment is growing increasingly complex, with a greater diversity of stakeholders involved in product development. Moves towards global software development with onshoring, offshoring, insourcing and outsourcing have seen a range of stakeholders introduced to the software development process, each with their own incentives and unders
In this article we prove NP-hardness of two well-known optimization problems related to the design of multicommodity flow networks with two different methods for providing network resiliency against failures: path diversity and flow restoration. Path diversity is a static mechanism that consists of using, for each demand, a number of paths and oversizing the flows assigned to these paths so that f
OBJECTIVE: Leukocyte-mediated tissue damage is a key feature in septic lung injury, although the signaling mechanisms behind pulmonary recruitment of leukocytes remain elusive. The aim of the present study was to define the role of p38 mitogen-activated protein kinase (MAPK) signaling in septic lung injury. DESIGN: Prospective experimental study. SETTING: University hospital research unit. SUBJECT
John 20:17 is often translated as if Jesus forbade Mary Magdalene to touch him after his resurrection. This is an old error, depending on misunderstanding the difference in aspect between the present and the aorist imperative in Greek.
Mutations in the gene encoding glucokinase (GCK) cause a mild hereditary form of diabetes termed maturity-onset diabetes of the young (MODY)2 or GCK-MODY. The disease does not progress over time, and diabetes complications rarely develop. It has therefore been suggested that GCK-MODY represents a metabolically compensated condition, but experimental support for this notion is lacking. Here, we pro
Objective. To describe the feasibility of robot-assisted laparoscopic myomectomy for unfavorably localized myomas using the da Vinci surgical system. Design. Prospective observational. Setting. University hospital. Method. Between April 2006 and March 2008, a robot-assisted laparoscopic myomectomy was performed on 13 women selected for having deep intramural myomas with probable impact on fertilit
In 2002 a group of men and women, coming from different professions but sharing an interest in social issues, joined together in a Citizens' Study (medborgarundersökning) in the Swedish city of Malmö. They were inspired by a classic Swedish citizens' study "Men of 1912" (1912 års män) which was a clandestine field study of the deplorable conditions in Stockholm's hostels in 1912. This book is a co
BACKGROUND AND PURPOSE: Widespread pain sensitivity in patients with FM suggests a CNS processing problem. The purpose of this study was to assess alterations in perfusion as measured by DSC in a number of brain regions implicated in pain processing between patients with FM and healthy controls. MATERIALS AND METHODS: Twenty-one patients with FM and 27 healthy controls underwent conventional MR i
We consider the capacity of multiple-input-multiple-output (MIMO) systems with reduced complexity. One link end uses all available antennas, while the other chooses the "best" L out of N antennas. The selection of the optimum antenna subset requires an exhaustive search of all possible combinations, involving (/sub L//sup N/) computations of determinants of size L /spl times/ L, which can become p
The threatened estate - the memorials of Per Brahe junior On the background of the present research on memorials and monuments follows a study of a number of memorials erected by the count Per Brahe junior between 1653 and 1680 on Visingsö and in Skärstad in Småland, at Dimbo in Västergötland and Östra Ryd in Uppland. The memorials belong to a period, when his county Visingsborg in Sweden and baro
Many small enterprises that are planning to implement environmental management systems (EMSs) and get certified according to the ISO 14001 standard or EMAS regulation have experienced a lot of barriers on the road towards certification. The standards are perceived as bureaucratic and represent a way of working that often fits poorly into the organizational culture and decision-making structure of
