Popular Abstract in Swedish Varje år drabbas cirka 700 kvinnor i Sverige av äggstockscancer. Det motsvarar två fulla X2000-tåg. Bara ett av dessa tåg med äggstockspatienter kommer att nå sitt mål - bot. Äggstockscancer är en ovanlig sjukdom och risken att drabbas är liten (jämfört med t.ex. bröstcancer, som fyller hela 22 tåg i Sverige), men prognosen är dyster. Färre än hälften av dem som får diaOvarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. However, ovarian cancer is a heterogeneous disease comprising different disease entities, which is of importance in clinical decision-mak

In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. The serotonin-transporter-linked promotor region (5-HTTLPR) was typed. More adversities were reported

Background: Few studies have compared the validity of objective measures of physical activity energy expenditure (PAEE) in pregnant and non-pregnant women. PAEE is commonly estimated with accelerometers attached to the hip or waist, but little is known about the validity and participant acceptability of wrist attachment. The objectives of the current study were to assess the validity of a simple s

Context. Several large scale photometric and spectroscopic surveys are being undertaken to provide a more detailed picture of the Milky Way. Given the necessity of generalisation in the determination of, e.g., stellar parameters when tens and hundred of thousands of stars are considered it remains important to provide independent, detailed studies to verify the methods used in the surveys. Aims. O

The trigeminovascular system plays a central role in migraine, a condition in need of new treatments. The neuropeptide, calcitonin gene-related peptide (CGRP), is proposed as causative in migraine and is the subject of intensive drug discovery efforts. This study explores the expression and functionality of two CGRP receptor candidates in the sensory trigeminal system.

The diffusion of mobile phones in low- and middle-income countries has taken place faster than any other infrastructural development. Mobile Midwife, a mobile application implemented in Ghana in 2010, sends timely messages in local languages to registered expectant mothers and new parents. The field of mobile health (mHealth) is severely underresearched, yet it can be an alternative for improving

Abstract People with psychiatric disabilities (PD) are a vulnerable group, and should be offered support and rehabilitation when needed. Day centres that provide individually matched daily occupations are an important link to provide that. The present study aimed at gaining knowledge regarding the occupations performed in day centres, in terms of the participants' descriptions of what they were do

Cassava peels were pre-treated with alkali, enzyme and in sequential combination of alkali and enzyme, and used for production of bioethanol or biogas, or both (in sequence, bioethanol followed by biogas). The Biogas Endeavour and Automatic Methane Potential Test Systems were used for production of bioethanol and biogas, respectively. The bioethanol yield and volumetric productivity achieved with

Background: Activating KRAS mutations are common in ovarian carcinomas of low histological grade, less advanced clinical stage and mucinous histological subtype, and form part of the distinct molecular alterations associated with type I tumors in the dualistic model of ovarian carcinogenesis. Here, we investigated the occurrence, clinicopathological correlates and prognostic significance of specif

Horismenus parasitoids are an abundant and understudied group of eulophid wasps found mainly in the New World. Recent surveys based on morphological analyses in Costa Rica have quadrupled the number of named taxa, with more than 400 species described so far. This recent revision suggests that there is still a vast number of unknown species to be identified. As Horismenus wasps have been widely des

The available energy (AE), driving the turbulent fluxes of sensible heat and latent heat at the earth surface, was estimated at four partly complex coniferous forest sites across Europe (Tharandt, Germany; Ritten/Renon, Italy; Wetzstein, Germany; Norunda, Sweden). Existing data of net radiation were used as well as storage change rates calculated from temperature and humidity measurements to final

Carbonyl compounds formed in sea buckthorn berry (Hippophae rhamnoides) and oil samples as a result of lipid oxidation were determined by enzymatic hydrolysis followed by derivatisation with 2,4-dinitrophenylhydrazine and analysed by LC-UV and electrospray ionisation (ESI) tandem mass spectrometry (MS/MS). Several classes of carbonyl compounds such as saturated, unsaturated, linear and branched al

Purpose: Prostate specific antigen velocity has been proposed as a marker to aid in prostate cancer detection. We determined whether prostate specific antigen velocity could predict repeat biopsy results in men with persistently increased prostate specific antigen after initial negative biopsy. Materials and Methods: We identified 1,837 men who participated in the Goteborg or Rotterdam section of

The possibilities of the use of structural reliability analysis in concrete dam design and assessment is investigated in Sweden. For such analysis, statistical descriptions of the loads and resistances are necessary. Uplift pressure has a large impact on safety, and is difficult to quantify. This paper describes the methodology of a geostatistical approach to simulate the uplift pressure, and an e

Abstract in Undeterminedhis survey deals with computational complexity of column generation problems arising in the design of survivable communication networks. Such problems are often modeled as linear programs based on noncompact multicommodity flow network formulations. These formulations involve an exponential number of path-flow variables, and therefore require column generation to be solved

Leadership is generally viewed as important and beneficial for individuals as well as organizations. The term, however, also implies followership and the targets for leadership may be less enthusiastic about adopting a follower position. From a follower’s point of view, there might be downsides associated with a leadership/followership relationship, including negative effects on identity and reduc

Abstract The chloroplast-localized NADPH-dependent thioredoxin reductase (NTRC) has been found to be able to reduce hydrogen peroxide scavenging 2-Cys peroxiredoxins. We show that the Arabidopsis ntrc mutant is perturbed in chlorophyll biosynthesis and accumulate intermediates preceding protochlorophyllide formation. A specific involvement of NTRC during biosynthesis of protochlorophyllide is indi