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Preparative chromatographic columns that run at high loads are highly sensitive to batch-to-batch disturbances of the process parameters, placing high demands on the strategy used for pooling of the product fractions. A new approach to pooling control is presented in a proof-of-concept study. A model-based sensitivity analysis was performed identifying the critical process parameters to product pu
The aim of the thesis is to discuss church building, the architectural design of Romanesque and Gothic churches and the use and symbolic interpretation of church buildings in the medieval period. It is suggested that churches were built for a variety of reasons, that the construction process may have been complicated and that the final result was not always the expected one. Many social groups wer
Our aim was to describe a large population-based cohort of diffuse large B-cell lymphoma (DLBCL) during the last decade, evaluating possible improvement in survival and to identify subgroups in need of novel treatment strategies. The study population encompassed all patients diagnosed with DLBCL in Sweden from 2000 through 2010. Altogether 5349 patients were identified. There was no increase in in
The relationship between Karl Pearson and the Scandinavian statisticians was more of a competitive than a collaborative nature. We describe the leading statisticians and stochasticists of the Scandinavian school, and relate some of their work to the work of Pearson.
Background-Retrospective studies have suggested that patients with a low transvalvular gradient in the presence of an aortic valve area <1.0 cm(2) and normal ejection fraction may represent a subgroup with an advanced stage of aortic valve disease, reduced stroke volume, and poor prognosis requiring early surgery. We therefore evaluated the outcome of patients with low-gradient "severe" stenosis (
Industrial robots are fast and accurate when working with known objects at precise locations in well-structured manufacturing environments, as done in the classical automation setting. In one sense, limited use of sensors leaves robots blind and numb, unaware of what is happening in their surroundings. Whereas equipping a system with sensors has the potential to add new functionality and increase
Travel in the footsteps of cinema is an expanding market, both in Sweden and internationally. Travel habits are changing, and the fact of a good number of people planning their journeys in order to follow in the footsteps of fictitiousn characters, or alternatively follow a particular route in order to experience first-hand something they saw at the cinema or on television, has become an important
This paper is the state of the art of charcoal signal studies (macro-, meso- and micro-charcoal) that have been carried out at the Epigravettian settlement of Mezhyrich. This work took part of the French ANR project "Mammouths". Charcoal signals have been found in both natural and archaeological (pits and activity areas) deposits that have been sampled during the 2007-2008 archaeological excavatio
It is often suggested that aesthetic and ethical value judgements are similar in such a way that they should be analysed in analogous manners. In this paper, I argue that the two types of judgements share four important, features concerning disagreement, motivation, categoricity, and argumentation. This, I maintain, helps to explain why many philosophers have thought that aesthetic and ethical val
Abstract in UndeterminedThe dominant explanation for China's unprecendented rates of economic growth in the last three decades has regarded them as the consequence of the reform policies that, after Mao, the Chinese leaders embarked upon in 1978. The present study, in contrast, argues for continuity between the socialist period and the post-refrom era in China's economic course.Chinse socialism, i
Neuroblastoma patients show remarkable clinical heterogeneity, with courses ranging from spontaneous regression to fatal tumor progression despite intense multi-modal treatment. Previous studies have shown that hypoxia pushes neuroblastoma cells towards a more immature phenotype, which correlates to aggressive disease. Here we define a role for the hypoxia inducible factor-2α in neuroblastoma tu
This thesis adds to the knowledge base of how the Individual Placement and Support (IPS) can be optimized to secure a more sustainable working career for people with severe mental illness (SMI). The thesis has given the IPS-participants an active voice about what it is like to start to work in a Swedish context, visualised the psychiatric disability in relation to work, discerned the support and p
We calculated average aquatic dissolved organic carbon (DOC) age (the time span from soil discharge to observation) in water from the inlets and outlets of two unproductive Swedish lakes at different times during an annual cycle. Bacterial production (BP) and bacterial growth efficiency (BGE) determined during 7-d bioassays decreased with increasing average aquatic DOC age. Parallel to the decline
Purpose: To investigate differences in calculated doses and normal tissue complication probability (NTCP) values between different dose algorithms. Methods: Six dose algorithms from four different treatment planning systems were investigated: Eclipse AAA, Oncentra MasterPlan Collapsed Cone and Pencil Beam, Pinnacle Collapsed Cone and XiO Multigrid Superposition, and Fast Fourier Transform Convolut
Some of the main bottlenecks for the development and commercialization of photovoltaic/thermal hybrids are the lack of an internationally recognized standard testing procedure as well as a method to compare different hybrids with each other and with conventional alternatives. A complete methodology to characterize, simulate and evaluate concentrating photovoltaic/thermal hybrids has been proposed
The PHENIX experiment at the Relativistic Heavy Ion Collider has measured omega meson production via leptonic and hadronic decay channels in p + p, d + Au, Cu+ Cu, and Au + Au collisions at root s(NN) = 200 GeV. The invariant transverse momentum spectra measured in different decay modes give consistent results. Measurements in the hadronic decay channel in Cu Cu and Au + Au collisions show that. p
