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The molecular mechanisms of nanosphere-induced mucosal immunization are important to decipher, since this can form the basis for novel approaches in, e.g., nasal vaccination. In this study, we have investigated the effect of nanospheres as antigen carriers on immature human dendritic cells. The results clearly indicate that tetanus toxoid immobilized nanospheres have a direct effect on human monoc
In order to induce local hyperthermia in superficial tumours a computer system using a 2,450 MHz microwave generator connected to a circular (diameter 90 mm) direct contact applicator was constructed based on invasive temperature control. Small thermistor probes with a diameter of 0.6 mm are inserted in the tumour and surrounding tissues. Eight thermistors can be used simultaneously and one of the
Adaptive estimation of the linear coefficient vector in truncated expansions is considered for the purpose of modeling noisy, recurrent signals. Two different criteria are studied for block-wise processing of the signal: the mean square error (MSE) and the least squares (LS) error. The block LMS (BLMS) algorithm, being the solution of the steepest descent strategy for minimizing the MSE, is shown
It is widely accepted that alkaline phosphatase activity (APA) is an efficient indicator of phosphate limitation in freshwater phytoplankton communities. In this study, we investigated whether the response in APA to phosphate limitation differs among the taxa in a mixed phytoplankton assemblage. We used the new enzyme-labeled fluorescence (ELF) technique, which allows microscopic detection of phos
A biofilm is a complex and diverse aggregation of microorganisms at surface comprised of among different things a protective adhesive matrix of extracellular polymeric substance. Biofilm research represents a broad range of sciences joining efforts within an interdisciplinary field of research. This thesis deals with the modeling of biofilms using the most fundamental laws of physics; the conserva
Foreword to texts by Maria Albin, Jonas Björk, Jonas Ardö, Erik Skärbäck and Tor Kihlman
The agricultural intensification strategies represented by the Green Revolution have since the mid-1960s had a very positive impact on food-grain production in Asia. Presently, however, a post-Green Revolution phase of declining growth in output and productivity is experienced in many of the areas where intensification took place. Partly, this can be explained by a number of environmental problems
I denna skrift visas ett antal beräkningsexempel på hur fuktinnehållet i en gotländsk sandsten kan variera med varierande randvillkor. Teorin och numerisk metod för beräkningarna beskrivs i detalj.
We have investigated the C-60 monolayer on Al(l 10) with angle-dependent photoelectron spectroscopy. We find that orbital components have different angular distributions. Calculations of cross sections of the highest occupied molecular orbital components for free, oriented C-60 are found to describe the experimental data quite well. The observed band splitting is attributed to intramolecular elect
The reaction mechanism for the selective catalytic oxidation of ammonia to give nitrogen on CuO/Al2O3, Pt/Al2O3 and Pt/CuO/Al2O3 was investigated using transient experiments. Temperature-programmed desorption and reaction of adsorbed ammonia indicated the formation of NHx species at the surface, and that this species is the precursor for the formation of nitrogen and nitrogen oxides. Pt/CuO/Al2O3
The differential alterations of the spliceosomal UsnRNAs (U1, U2, U4, U5, and U6) were reported to be associated with cellular proliferation and development. The attempt was made in this study to analyze the metabolic pattern of the spliceosomal UsnRNAs during the development of pre-malignant lung lesions induced in experimental mice model system by benzo(a)pyrene (BP) and also to see how tea poly
In systemic radiation therapy, the absorbed dose distribution must be calculated from the individual activity distribution. A computer code has been developed for the conversion of an arbitrary activity distribution to a 3-D absorbed dose distribution. The activity distribution can be described either analytically or as a voxel based distribution, which comes from a SPECT acquisition. Decay points
Reflections on Danish and Scandinavian church archaeology focusing on three turningpoints, where new perspectives are introduced: Around 1950, 1980 and 2000. Implicit three periods are presented in the history of church archaeology, 1950-80, 1980-2000, and after 2000. The new perspectives are followed by new ways of illustrating the churches.
The research described in this thesis, focuses on some activities on the demand side that could reduce peak load in electricity system by using consumer flexibility i.e. by increasing the demand side response to signals coming from the energy market. The major objective is to test and analyse different strategies to reduce peak load at the demand side considering their techno-economic, environment
Attosecond pulse emission using a laser field with time-dependent ellipticity is studied experimentally and theoretically. Our theoretical approach is validated by comparison with experimental VUV spectra. We show in calculations that the VUV emission can be confined into a narrow temporal window in which the fundamental polarization is quasi-linear. We find an analytical equation describing the d
In this work, the interfacing of a poly(ethylene glycol) (PEG)-phosphate aqueous two-phase system with hydrophobic interaction chromatography (HIC) for primary recovery of an intracellular protein was evaluated. As a model protein, a recombinant cutinase furnished with a tryptophan-proline (WP) peptide tag was used and produced intracellularly in Escherichia coli (E. coli). E. coli cell homogenate
