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Benefits, for patients with late stage chronic obstructive pulmonary disease, of being cared for in specialized palliative care compared to hospital. A nationwide register study

Background: In early stage chronic obstructive pulmonary disease (COPD), dyspnea has been reported as the main symptom; but at the end of life, patients dying from COPD have a heavy symptom burden. Still, specialist palliative care is seldom offered to patients with COPD; they more often receive end of life care in hospitals. Furthermore, symptoms, symptom relief and care activities in the last we

Digi-Do : a digital information tool to support patients with breast cancer before, during, and after start of radiotherapy treatment: an RCT study protocol

Background: Radiation Therapy (RT) is a common treatment after breast cancer surgery and a complex process using high energy X-rays to eradicate cancer cells, important in reducing the risk of local recurrence. The high-tech environment and unfamiliar nature of RT can affect the patient’s experience of the treatment. Misconceptions or lack of knowledge about RT processes can increase levels of anx

Annual dementia incidence and monetary burden attributable to fine particulate matter (PM2.5) exposure in Sweden

Background: Alzheimer’s disease (AD) and other dementias currently represent the fifth most common cause of death in the world, according to the World Health Organization, with a projected future increase as the proportion of the elderly in the population is growing. Air pollution has emerged as a plausible risk factor for AD, but studies estimating dementia cases attributable to exposure to fine

Psychometric properties of the Inventory of Life Quality in children and adolescents in Norwegian Sign Language

Background: Several studies have assessed the Quality of Life (QoL) in Deaf and hard-of-hearing (DHH) children and adolescents. The findings from these studies, however, vary from DHH children reporting lower QoL than their typically hearing (TH) peers to similar QoL and even higher QoL. These differences have been attributed to contextual and individual factors such as degree of access to communi

Head-to-head comparison of a Si-photomultiplier-based and a conventional photomultiplier-based PET-CT system

Background: A novel generation of PET scanners based on silicon (Si)-photomultiplier (PM) technology has recently been introduced. Concurrently, there has been development of new reconstruction methods aimed at increasing the detectability of small lesions without increasing image noise. The combination of new detector technologies and new reconstruction algorithms has been found to increase image

Clinical characteristics and histopathological patterns of hodgkin lymphoma and treatment outcomes at a tertiary cancer center in ethiopia

PURPOSE In developing countries, Hodgkin lymphoma (HL) affects the young population. In Ethiopia, nearly 70% of the population are, 35 years of age. Therefore, this study aimed to elucidate the age distribution, histopathologic patterns, clinical characteristics and treatment outcomes of HL in Ethiopia. MATERIALS AND METHODS Data from clinical records of 133 consecutive patients with HL between 20

11C-Metomidate PET/CT Detected Multiple Ectopic Adrenal Rest Tumors in a Woman with Congenital Adrenal Hyperplasia

Context: Women with congenital adrenal hyperplasia (CAH) may present with androgen excess that is difficult to control with conventional suppressive doses of glucocorticoids. Clinical management is challenging, and the woman is at great risk of developing steroid-induced complications. Patients and Methods: A 32-year-old woman with salt-wasting CAH due to 21-hydroxylase deficiency underwent right-

Advances in Type 1 Diabetes Prediction Using Islet Autoantibodies : Beyond a Simple Count

Islet autoantibodies are key markers for the diagnosis of type 1 diabetes. Since their discovery, they have also been recognized for their potential to identify at-risk individuals prior to symptoms. To date, risk prediction using autoantibodies has been based on autoantibody number; it has been robustly shown that nearly all multiple-autoantibody-positive individuals will progress to clinical dis

From Intrauterine to Extrauterine Life—The Role of Endogenous and Exogenous Factors in the Regulation of the Intestinal Microbiota Community and Gut Maturation in Early Life

Differentiation of the digestive tube and formation of the gut unit as a whole, are regulated by environmental factors through epigenetic modifications which enhance cellular plasticity. The critical period of DNA imprinting lasts from conception until approximately the 1,000th day of human life. During pregnancy, besides agents that may directly promote epigenetic programming (e.g., folate, zinc,

Who Cares? : The Neoliberal Turn and Changes in the Articulations of Women’s Relation to the Swedish Welfare State

This article aims to investigate how articulations of women’s relation to the welfare state and modes of political agency has changed in Sweden between 1977 and 2017; a period characterized by the introduction and implementation of a neoliberal political rationality. By way of discourse analysis, the article highlights the reciprocal relationship between the construction of the welfare state and w

Initial Analysis of Dynamic Panel Activation for Large Intelligent Surfaces

Large intelligent surfaces (LIS) have the potential to be the beyond-massive-MIMO solution, even further improving spectral efficiency, coverage, reliability and other performance measures. They also open up for entirely new services, such as precise localization, environment sensing, and wireless energy transfer. By constructing larger surfaces as a grid of panels, we can activate and deactivate

Consequences of APSP, triangle detection, and 3SUM hardness for separation between determinism and non-determinism

Let NDTIME(f(n),g(n)) denote the class of problems solvable in O(g(n)) time by a multi-tape Turing machine using an f(n)-bit non-deterministic oracle, and let DTIME(g(n)) = NDTIME(0, g(n)). We show that if the all-pairs shortest paths problem (APSP) for directed graphs with N vertices and integer edge weights within a super-exponential range { -2Nk+o(1),.,2Nk+o(1)}, k≥1 does not admit a truly subc

Manifestation of panuveitis after intraocular surgery in a child with blau syndrome

Blau syndrome (BS) is a rare granulomatous disease with autosomal dominant inheritance. It is characterized by a triad of dermatitis, arthritis, and recurrent uveitis. This case presents the onset of panuveitis in BS after intraocular surgery. A 10-year-old boy presented to the outpatient clinic with retinal detachment in the left eye after 6 years following early-onset cataract surgery. Bilateral

Enhancing neuronal inhibition by cell and gene therapy as a novel treatment for Epilepsy

Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people worldwide of all ages and genders. Available treatments are only symptomatic and have severe side effects, while they also fail to provide adequate seizure control in a third of the patients. Therefore, a cure is yet to

Coordination during Cholera Outbreak Response : Critical Insights from Yemen

Within the humanitarian arena and since the introduction of the humanitarian reform process in 2005, the cluster approach was introduced to strengthen the cooperation and accountability between agencies working in the same field. Such an integrated approach is particularly needed and relevant in emergencies like cholera, especially in countries undergoing internal conflicts like Yemen. Several are

Let’s move beyond word battles and separatism: Strategies and concerns regarding Universal Design in Sweden

Purpose – Universal design (UD) is defined in the United Nations Convention on the Rights of Persons with Disabilities (UNCRPD) and adopted in Sweden as a guiding principle for the design of new products, facilities, services, etc. This study aims to contribute to knowledge about UD in practice – how it is conceived,experienced and discussed in Sweden, especially regarding education, working life

Four Decades of Air Temperature Data over Iran Reveal Linear and Nonlinear Warming

Spatiotemporal analysis of long-term changes in air temperature is of prime importance for climate change research and the development of effective mitigation and adaptation strategies. Although there is considerable research on air temperature change across the globe, most of it has been on linear trends and time series analysis of nonlinear trends has not received enough attention. Here, we anal