An extensive variety of THAP1 sequence variants have been associated with focal, segmental and generalized dystonia with age of onset ranging from 3 to over 60 years. In previous work, we screened 1114 subjects with mainly adult-onset primary dystonia (Neurology 2010; 74:229-238) and identified 6 missense mutations in THAP1. For this report, we screened 750 additional subjects for mutations in cod

Thrips (Thysanoptera) are tiny insects that produce anal secretions whenthreatened. Several studies have shown that, depending on the species,the droplets may contain alarm pheromones and/or repellents againstenemies. In the eusocial gall-inducing thrips Kladothrips intermedius bothlarvae and adults produce such droplets. There are two castes of adults inthis species, soldiers (the sub-fertile and

Six-membered cyclic carbonates with hydroxyl and/or alkoxycarbonyloxy groups, as potential monomers for polyurethanes and polycarbonates, were prepared by the reaction between trimethylolpropane (TMP) with dimethyl carbonate (DMC) or diethylcarbonate (DEC) mediated by immobilized Candida antarctica lipase B, NovozymR (R) 435 in a solvent-free medium. The dialkyl carbonate served as a solvent for t

It has been suggested that plants are able to increase radiative heat dissipation from their leaves by depositing near-surface silica, in this way increasing emissivity of infrared radiation and lowering leaf temperature. In order to test this theory, we have compared emissivity and radiative dissipation over the mid-infrared range 2.5–22.3 lm of leaves of plants that accumulate silica and plants

Micro or even nano-scale solid particles are applied in porous structures in different energy systems, such as fuel cells, for the objectives to enhance the catalytic reaction activities and improve the fuel utilization efficiency or/and reduce the pollutants. In addition to the charge transport and reactions, heat transfer processes in fuel cell porous electrodes are strongly affected by the smal

In order to increase the understanding of how students assimilate the knowledge they need to carry out their professional duties, knowledge about the experience of the nursing education in the light of the first year of employment is important. The aim of this study was to describe nurses' views of their education, one year after their graduation. Interviews with eight nurses, aged 24 to 40 years,

Pressure on healthcare budgets is increasing, while at the same time patent protection for many branded inhaled medications has expired, leading to the development and growing availability of generic inhaled medicines. Generic inhaled drugs are therapeutically equivalent to original branded options but may differ in their formulation and inhalation device. This new situation raises questions about

The protective effect of a multi-strain probiotic and synbiotic formulation was evaluated in C57BL/6 mice infected with Clostridium difficile (CD) NAP1/027. Antibiotic treated mice were divided into four groups. Group 1, fed with a synbiotic formulation consisting of Lactobacillus plantarum F44, L. paracasei F8, Bifidobacterium breve 46, B. lactis 8:8, galacto-oligosaccharides (GOS), isomalto-olig

The climatic conditions inside nuclear reactor containments are continuously monitored by the plant owners in order to e.g. maintain a suitable climate for the mechanical and electrical equipment. Due to the high temperatures, during operation, the concrete within the containment may act as a moisture source contributing to the humidity. To evaluate if, and to what extent, the concrete inside the

A measurement is reported of the production cross section of top-quark pairs (t (t) over bar) in proton-proton collisions at a center-of-mass energy of 7 TeV recorded with the ATLAS detector at the LHC. Candidate events have a signature consistent with containing two isolated leptons, large missing transverse momentum, and at least two jets. Using a data sample corresponding to an integrated lumin

For clinical proteomic studies the availability of high quality biofluid samples such as human blood plasma are extremely important. In this study we have investigated the stability of human plasma samples by spiking stable isotope-labeled peptides into the plasma and monitoring their degradation under different storage conditions. FPA-1, C4A and C3f were synthesized with isotopically labeled amin

Measurements of four-lepton (4ℓ, ℓ=e,μ) production cross sections at the Z resonance in pp collisions at the LHC with the ATLAS detector are presented. For dilepton and four-lepton invariant mass regions m_{ℓ^{+}ℓ^{-}}>5 GeV and 80

Molecular spiders are synthetic biomolecular walkers that use the asymmetry resulting from cleavage of their tracks to bias the direction of their stepping motion. Using Monte Carlo simulations that implement the Gillespie algorithm, we investigate the dependence of the biased motion of molecular spiders, along with binding time and processivity, on tunable experimental parameters, such as number

This concerns Flow Induced Vibrations (Fly) in nuclear reactors and numerical analysis of such. Special attention is paid to structural excitation by sound generated remotely and turbulent flow around the structure. One hypothesis was that these phenomena can interact, so that the structure accumulates more energy from the flow if it also excited by sound from another source. In the studies, Fluid

ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to

Semiconductor devices are heavily dependent on dopant incorporation in order to control the electrical properties. In this paper we investigate the possibility of using gates wrapped around a nanowire (NW) channel as a way of tuning the Fermi level position, in certain cases removing the need for dopants and providing a more dynamical way of setting the device properties. InP NW devices with omega