HIV-1 transmission patterns within and between populations at different risk of HIV-1 acquisition in Kenya are not well understood. We investigated HIV-1 transmission networks in men who have sex with men (MSM), injecting drug users (IDU), female sex workers (FSW) and heterosexuals (HET) in coastal Kenya. We used maximum-likelihood and Bayesian phylogenetics to analyse new (N = 163) and previously

Transport is frequently cited as one of the most expedient means by which humankind affects Earth's ecosystem. Indeed, as underscored by the Anthropocene proposition, transport-related impacts are significant to the point of resulting in alterations of the planet's geological structure. Rising awareness of such issues has led to increasing attention on the priority of achieving a radically decarbo

Diffusion is a reoccurring phenomena in many fields and is affected by the geometry in which it takes place. Here we investigate the effects of geometry on diffusion in a Brick and Mortar model system. The tortuous effects are evaluated based on generalized Fick's law, i.e. diffusion driven by differences in chemical potential. The presented formalism gives a general (semi-) exact analytic express

We present the macroscale three-dimensional numerical solution of anisotropic Biot's poroelasticity, with coefficients derived from a micromechanical analysis as prescribed by the asymptotic homogenisation technique. The system of partial differential equations (PDEs) is discretised by finite elements, exploiting a formal analogy with the fully coupled thermal displacement systems of PDEs implemen

Dispersal is a key process affecting population persistence and major factors affecting dispersal rates are the amounts, connectedness and properties of habitats in landscapes. We present new data on the butterfly Maniola jurtina in flower-rich and flower-poor habitats that demonstrates how movement and behaviour differ between sexes and habitat types, and how this effects consequent dispersal rat

An increasing demand for dairy products with long shelf-life is foreseen. A limiting factor for maintaining high quality of these products is the activity of spoilage enzymes during storage. Lipase and protease activities in Swedish raw milk at farm and dairy level were investigated, analysing milk samples from three geographical regions and two seasons. Lipase activity in milk at farm level was a

Brown macroalgae (Phaeophyta) hold high potential as feedstock for biorefineries due to high biomass productivity and carbohydrate content. They are, however, a challenging, unconventional feedstock for microbial refining and several processing problems need to be solved to make them a viable option. Pre-treatment is necessary to enhance accessibility and solubility of the biomass components but s

Acetylated, propionylated and butyrylated rice and quinoa starches at different levels of modification and starch concentrations, were used to stabilize oil-in-water starch Pickering emulsions at 10% oil fraction. Short-chain fatty acid modified starch Pickering emulsions (SPEs) were characterized after emulsification and after 50 days of storage. The particle size distribution, microstructure, em

Optimum operating conditions of a fuel cell will provide its maximum efficiency and the operating cost will be minimized. Thus, operation optimization of the fuel cell is essential. Neural networks can simulate systems without using simplifying assumptions. Therefore, the neural network can be used to simulate complex systems. This paper investigates the effects of important parameters, i.e., temp

A continuous integrated bioprocess available from the earliest stages of process development allows for an easier, more efficient and faster development and characterization of an integrated process as well as production of small-scale drug candidates. The process presented in this article is a proof-of-concept of a continuous end-to-end monoclonal antibody production platform at a very small scal

We apply the Atkinson (1970) inequality index to time series of asset returns to offer a novel measure of financial risk consistent with expected-utility theory. This measure is converted to a certainty-equivalent return serving as a performance measure. We extend the Atkinson index to HARA utility and derive closed-form solutions to our measures for a number of preference-return combinations. Fur

In recent years, increasing inlet temperature of gas turbines has far exceeded the melting point of the metal materials. Film cooling technology has widely been used to protect gas turbine blades from erosion of the high-temperature gases. The film cooling performance can be improved by optimization of the hole configurations. Results show that the backward injection hole has a smaller exit moment

Background: Since long travel times to reach health facilities are associated with worse outcomes, geographic accessibility is one of the six core global surgery indicators; this corresponds to the second of the “Three Delays Framework,” namely “delay in reaching a health facility.” Most attempts to estimate this indicator have been based on geographical information systems (GIS) algorithms. The a

The elliptic flow (v2) of (anti-)3He is measured in Pb–Pb collisions at sNN=5.02TeV in the transverse-momentum (pT) range of 2–6 GeV/c for the centrality classes 0–20%, 20–40%, and 40–60% using the event-plane method. This measurement is compared to that of pions, kaons, and protons at the same center-of-mass energy. A clear mass ordering is observed at low pT, as expected from relativistic hydrod

We evaluated the joint associations between a new 313-variant PRS (PRS313) and questionnaire-based breast cancer risk factors for women of European ancestry, using 72,284 cases and 80,354 controls from the Breast Cancer Association Consortium. Interactions were evaluated using standard logistic regression, and a newly developed case-only method, for breast cancer risk overall and by estrogen recep

Within rheumatology, telehealth is essential to modern rehabilitation due to the demographic development with more and more elderly people. At present, telehealth solutions are used as part of the rehabilitation process in assessment, interventions and evaluation. Telehealth interventions are as effective as conventional follow-ups or self-management assessments, but the evidence on the effect is

Nigeria has the highest number of AIDS-related deaths in the world. In this study, we characterised the HIV-1 molecular epidemiology by analysing 1442 HIV-1 pol sequences collected 1999-2014 from four geopolitical zones in Nigeria using state-of-the-art maximum-likelihood and Bayesian phylogenetic analyses. The main circulating forms were the circulating recombinant form (CRF) 02_AG (44% of the an

Autonomous vehicle functions in safety-critical situations show promise in reducing the risk and saving lives in accidents compared to existing safety systems. Consequently, it is from many perspectives advantageous to be able to quantify the potential benefits of new autonomous systems for vehicle maneuvers at-the-limit of tire friction. Here, to estimate the potential in terms of saved lives and