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There are specific receptors for the active metabolite of vitamin D on the pancreatic beta cells and severe vitamin D deficiency can inhibit insulin secretion. In the present study 14 middle aged men with impaired glucose tolerance and low glucose-stimulated insulin values received 2 micrograms alphacalcidol daily for 18 months. On treatment there was a transient increase of both the peak and the
Abstract in Undetermined A selective overview of Swedish Bronze Age research during the late 1980s is presented. The dominant topics were settlement archaeology, spatial analysis, bronze metalwork and rock art with local or regional perspectives. Both generalistic and particularistic approaches are not- able with the use of quantitative and qualitative methods in a search of comprehensive views fo
The Cromer blood group system consists of eight high incidence and three low incidence antigens carried on decay-accelerating factor (DAF). This report describes the identification and characterization of a new Cromer high incidence antigen, named SERF. Sequence analyses of DNA from a Thai female whose serum contained the alloantibody to a high incidence antigen in the Cromer blood group system (a
We describe the purification of lacrimal gland plasma membranes by affinity partitioning using a two-phase system containing polyethylene glycol and dextran in which wheat germ agglutinin conjugated to dextran is used as affinity ligand. When partitioning a microsomal fraction, the plasma membrane marker 5'-nucleotidase was obtained in the affinity ligand-containing bottom phase, whereas the endop
Brain-derived neurotrophic factor (BDNF), aside from its classic neurotrophic role in development and survival of neurons, has been shown to be involved in modification and plasticity of central synapses. In mice with BDNF gene deletion (BDNF+/-), deficits in synaptic transmission are often observed but are reversed readily by administration of BDNF, suggesting its acute effect. In support, blocka
BACKGROUND: The S-s-U- phenotype in African Americans is due to a GYPB deletion, however the molecular basis for the S-s-U+var phenotype is poorly understood. Variable reactivity of S-s-U+var RBCs with monoclonal anti-He or by anti-U has been demonstrated, however the underlying molecular bases for this phenotype remain to be established. STUDY DESIGN AND METHODS: Hemagglutination was performed on
A set of measurement with moveable aperture restrictions, also called scrapers, has been carried out at MAX II (Nucl. Instr. and Meth. A 343 (1994) 644), the 1.5GeV electron storage ring at MAX-lab, Lund, Sweden. The measurements with scrapers in MAX 11 have shown to give a number of useful results, such as the vertical and horizontal acceptance, which are 7.4 x 10(-6) and 9.6 x 10-6 m, respective
Depth buffer performance is crucial to modern graphics hardware. This has led to a large number of algorithms for reducing the depth buffer bandwidth. Unfortunately, these have mostly remained documented only in the form of patents. Therefore, we present a survey on the design space of efficient depth buffer implementations. In addition, we describe our novel depth buffer compression algorithm, wh
Human script culture is not limited to texts of learning and entertainment. By the use of script and print technology to communicate and preserve, societies have grown. Graphic messages pervade cities as commercial and communal signs, and the long dependance on print in society is shown as well by all the ephemeral products of job printing as by the symbolic position of the book in religions. This
P-Microseminoprotein (MSP) and cysteine-rich secretory protein 3 (CRISP-3) are abundant constituents of human seminal plasma. Immunoprecipitation and gel filtration of seminal plasma proteins combined with examination of the proteins in their pure form showed that MSP and CRISP-3 form stable, non-covalent complexes. CRISP-3 binds MSP with very high affinity, as evidenced by surface plasmon resonan
We report on the formation of an attractive potential around buried metal wires in a novel design for the Hot Electron Transistor (HET). In this device, the doped base layer in the HET is replaced by an embedded metal grating, which is forward biased beyond flat band conditions in order to efficiently extract carriers from the emitter into the active region. These carriers are collected in a Schot
We explore here, through three complementary experiments on virtual objects, how intimate active relations with multisensory audio-visual and haptics perceptions allow to the cognitive creation of new believable and plausible objects that can be different of the virtual ones objectively implemented. The three experiments are based on "Pebble Boxes" and consist in the exploration and the manipulati
System Thinking is the mindset of defining and confining a problem and its symptoms as well as a method for communicating system understanding. System Analysis is taking that problem apart to understand its causalities and structural arrangement. System Dynamics is the use of the results of System Analysis in order to reconstruct the system of causalities. Modelling is used for understanding comp
Neuropeptide Y is a sympathetic co-neurotransmitter released with noradrenaline upon sympathetic nerve stimulation. This study describes the ability of a synthetic inositol phosphate, alpha-trinositol(D-myo-inositol 1,2,6-triphosphate; PP 56) to antagonize vasoconstrictor responses to neuropeptide Y in-vitro as well as in-vivo. In human and guinea-pig isolated arteries alpha-trinositol potently (1
We investigated the role of the major histocompatibility complex (MHC) region in the specificity of autoimmunity by analysing specifically the development of sialadenitis, but also insulitis, nephritis and autoantibody production in autoimmune-prone nonobese diabetic (NOD) mice where the MHC H2g7 haplotype had been exchanged for the H2q (NOD.Q) or H2p (NOD.P) haplotype. The exchange of H2 haplotyp
