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BACKGROUND: Several studies have sought to investigate gambling craving and its potential contribution to gambling problems. One aim of this line of research has been to further examine whether craving should be considered a separate diagnostic criterion for gambling disorder, which it currently is not. The present study aimed to investigate the relationship between craving and other risk factors—

ObjectiveDopaminergic medications are commonly prescribed for Parkinson's disease (PD), restless legs syndrome, pituitary and psychotic disorders. Accumulating evidence indicates that dopaminergic treatment triggers impulsive-compulsive behaviors (ICBs), yet systematic synthesis of clinical evidence remains limited.MethodThis scoping review summarizes original research directly clinically relevant

OBJECTIVE: It is unknown how risk factors for infection after transrectal prostate biopsy interact. We designed a study to evaluate this.METHODS: We identified biopsy procedures from 2006 to 2020 in the Swedish nationwide database PCBaSe. Primary outcome was post-biopsy infection, defined as a dispensed prescription of a urinary tract antibiotic and secondary outcome was inpatient care for infecti

ImportanceGuidelines for temperature control following out-of-hospital cardiac arrest (OHCA) are based on trials with end points of 180 days or fewer.ObjectivesTo investigate if targeted hypothermia, compared with targeted normothermia with early treatment of fever, affects functional outcome focusing on societal participation or cognitive functioning at 24 months in initially comatose OHCA survivImportanceGuidelines for temperature control following out-of-hospital cardiac arrest (OHCA) are based on trials with end points of 180 days or fewer.ObjectivesTo investigate if targeted hypothermia, compared with targeted normothermia with early treatment of fever, affects functional outcome focusing on societal participation or cognitive functioning at 24 months in initially comatose OHCA surviv

OBJECTIVES: Implementation of the Stroke Action Plan for Europe (2018-2030) (SAP-E) was initiated in 2019. It is now updated at mid-term to reflect and respond to challenges for stroke care in Europe in 2025. METHODS: The SAP-E covers the entire chain of stroke care. The sections (state of the art, current status and targets) were developed by working groups and finalised based on inputs from the

Using population-wide data on Swedish university researchers and teachers, we identify the effects of parenthood on academic careers. Leveraging staggered event-study models that compare mothers and fathers around first birth, we document widening gender gaps in publication output, wage income, promotion, and PhD completion. These gaps arise across all scientific fields. We further document substa

We provide a detailed characterization of the planetary system orbiting HD 85426 (TOI-1774). This bright G-type star (: 0.99;: 1.13; age: 7.4 Gyr; V mag: 8.25) hosts a transiting sub-Neptune, HD 85426 b, with an orbital period of 16.71 d and a blackbody equilibrium temperature of K. By jointly analysing HARPS-N RVs, TESS, and CHEOPS photometric data and using two different stellar activity mitigat

Over four decades, Indigenous Sámi individuals and communities have submitted to United Nations human rights treaty bodies, including the Human Rights Committee, several complaints in respect of the three Nordic countries Finland, Norway, and Sweden. Many of these Sámi rights cases have made important contributions to the understanding and application of Indigenous peoples’ rights globally, in add

Mental simulation theories of language comprehension propose that people automatically create mental representations of objects mentioned in sentences. Mental representation is often measured with the sentence-picture verification task, wherein participants first read a sentence that implies the object property (i.e., shape and orientation). Participants then respond to an image of an object by in

This paper examines how violent conflict affects the supply of education in one of the world’s poorest countries, Burkina Faso. We combine unique nationwide census data on all primary schools with geocoded records of Islamist violence to assess how local conflict exposure shapes school availability, staffing, and the mix of education provision. Using a staggered difference-in-differences design anThis paper examines how violent conflict affects the supply of education in one of the world’s poorest countries, Burkina Faso. We combine unique nationwide census data on all primary schools with geocoded records of Islamist violence to assess how local conflict exposure shapes school availability, staffing, and the mix of education provision. Using a staggered difference-in-differences design an

This paper examines whether and how Islamist violence affects educational content in secondary schools in Burkina Faso. We combine geocoded conflict-event data with nationwide school census data containing detailed information on teachers’ subject-specific teaching hours and mobility across schools. Using a staggered difference-in-differences design, we estimate the dynamic effects of violence on This paper examines whether and how Islamist violence affects educational content in secondary schools in Burkina Faso. We combine geocoded conflict-event data with nationwide school census data containing detailed information on teachers’ subject-specific teaching hours and mobility across schools. Using a staggered difference-in-differences design, we estimate the dynamic effects of violence on

Background: The association between lifestyle factors and Alzheimer's disease (AD) pathophysiology remains incompletely understood. Objective: The aim of this study was to assess the association of alcohol consumption, smoking behavior, sleep quality and physical, cognitive, and social activity with cerebral amyloid pathology. Methods: For this cross-sectional study, we selected participants from

The human blood proteome provides a holistic readout of health states through the assessment of thousands of circulating proteins. In this study, we present a pan-disease resource to enable the study of diverse disease phenotypes within a harmonized proteomics dataset. by profiling protein concentrations across 59 diseases and healthy cohorts, we identified proteins associated with age, sex, and b

Background Inversions involving intron 22 (Inv22) of the F8 gene are detected in approximately 45% of all severe hemophilia A (HA) patients. Digital droplet polymerase chain reaction using milepost assays and multiplex ligation-dependent probe amplification (MLPA) allows robust diagnosis of inversions, copy number variations, and more complex rearrangements in F8 . Objectives A total of 350 HA pat

När föräldrar har låga inkomster minskar barnens möjligheter att exempelvis resa på semester eller delta i fritidsaktiviteter som kostar pengar. Att växa upp i ekonomisk utsatthet kan påverka barns framtidsutsikter negativt. Av den offentliga statistiken vet vi att barnfattigdom är vanligare bland familjer med utrikes födda föräldrar, men variationen inom gruppen är stor och delvis outforskad.I de

This chapter challenges the widespread belief that shopping provides lasting happiness and stress relief. This myth, often referred to as ‘retail therapy’, suggests that consumption serves as an effective coping mechanism for emotional distress. Rooted in post-war consumer culture and reinforced by advertising, this idea has normalised the use of material goods to manage emotions, fostering a depe

In this paper we review the physics opportunities at linear e+e− colliders with a special focus on high centre-of-mass energies and beam polarisation, take a fresh look at the various accelerator technologies available or under development and, for the first time, discuss how a facility first equipped with a technology that is mature today could be upgraded with technologies of tomorrow to reach m

Cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) imaging shows myocardial fibrosis and is associated with outcome in repaired Tetralogy of Fallot (rToF). However, patients with rToF have surgical material implanted, also appearing bright in LGE images. Therefore, right ventricular myocardial fibrosis could be overestimated or falsely diagnosed, which may affect prognostic va

The Swedish music and arts school (SAMS) has been described as “a foundation for Swedish culture, where children and youth are given opportunities to express themselves through dance, fine art, drama, music or other art forms” (Öhrman & Holmdahl, 2022, s. 103). Current debates have questioned SAMS capacity to meet contemporary needs, revolving around themes such as broadening of target groups,The Swedish music and arts school (SAMS) has been described as “a foundation for Swedish culture, where children and youth are given opportunities to express themselves through dance, fine art, drama, music or other art forms” (Öhrman & Holmdahl, 2022, s. 103). Current debates have questioned SAMS capacity to meet contemporary needs, revolving around themes such as broadening of target groups,