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The use of ethylenediaminetetraacetic acid as enhancing agent for the remediation of a lead polluted soil

Result: for Pb extraction experiments from a contaminated soil performed with citric acid and ethylenediaminetetraacetic acid disodium salt (Na(2)EDTA) indicate that Na(2)EDTA is much more efficient. The Pb removal after 5 successive extractions using 24 mL of 0.1 M Na(2)EDTA solutions and 8 g of soil is close to 100%. Other non-toxic metals such as Ca and Mg, that are present in important concent

The journey of recovery and empowerment embraced by nature - clients' perspectives on nature-based rehabilitation in relation to the role of the natural environment.

This paper presents findings from real life situations, a longitudinal single case study on the role of natural environments in nature-based rehabilitation (NBR) for individuals with stress-related mental disorders, at the Alnarp Rehabilitation Garden in Sweden. A sample of 43 former clients voluntarily participated in semi-structured interview, and the data were analyzed according to interpretati

Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B

Replacement therapy with factor IX (FIX) concentrates is the recommended treatment for patients with hemophilia B, an X-linked bleeding disorder occurring in 1: 25 000 male births. N9-GP is a recombinant FIX molecule with a prolonged half-life which is obtained by site-directed glycoPEGylation where a 40-kDa polyethylene glycol molecule is attached to the activation peptide of FIX. This first huma

Neighbourhood deprivation and lung cancer incidence and mortality: a multilevel analysis from Sweden.

Neighbourhood deprivation has been implicated in lung cancer but no study has simultaneously analysed the potential effect of neighbourhood deprivation on both lung cancer incidence and mortality, after adjusting for individual-level socioeconomic factors, and comorbidities. The aim of the present study was to analyse whether there is an association between neighbourhood deprivation and incidence

Comments: The role of attention in lexical semantics

I take up the roles of the world, the mind and the society in my semantic theory. I show how semantic differences between languages can be seen as attending to different parts of event structures. The role of the emotion domain in relation to the meaning of pejoratives is discussed. Finally, the idea that articles in language should be seen as an extension of pointing is shown to be congenial with

Collagen VI Is a Subepithelial Adhesive Target for Human Respiratory Tract Pathogens

Bacterial engagement of specific host tissue structures can be a means of targeting a pathogen to a particular niche, establishing persistent infections and inducing invasion. In this context, primary adhesion is often the first crucial colonization step allowing pathogens to withstand the mechanical clearing mechanisms of the host. As a consequence, bacteria have evolved adhesins with the capacit

Validity and Responsiveness of At-Home Touch Screen Assessments in Advanced Parkinson's Disease

The aim of this study was to investigate if a telemetry test battery can be used to measure effects of Parkinson's disease (PD) treatment intervention and disease progression in patients with fluctuations. Sixty-five patients diagnosed with advanced PD were recruited in an open longitudinal 36-month study; 35 treated with levodopa-carbidopa intestinal gel (LCIG) and 30 were candidates for switchin

A novel enterovirus and parechovirus multiplex one-step real-time PCR-validation and clinical experience

As the number of new enteroviruses and human parechoviruses seems ever growing, the necessity for updated diagnostics is relevant. We have updated an enterovirus assay and combined it with a previously published assay for human parechovirus resulting in a multiplex one-step RT-PCR assay. The multiplex assay was validated by analysing the sensitivity and specificity of the assay compared to the res

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment.

This article examines the foundation of β-cell failure in type 2 diabetes (T2D) and suggests areas for future research on the underlying mechanisms that may lead to improved prevention and treatment.RESEARCH DESIGN AND METHODS: A group of experts participated in a conference on 14-16 October 2013 cosponsored by the Endocrine Society and the American Diabetes Association. A writing group prepared t

Structural, microstructural, and thermal characterizations of a chalcopyrite concentrate from the Singhbhum shear zone, India

The structural and morphological characterizations of a chalcopyrite concentrate, collected from the Indian Copper Complex, Ghatshila, India, were carried out by X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. The concentrate powder was composed mainly of free chalcopyrite and low quartz in about 3:1 weight ratio. The particle size was about 100 mu m. Spe

Cardiovascular event in systemic lupus erythematosus in northern Sweden: Incidence and predictors in a 7-year follow-up study

Introduction. An increased rate of cardiovascular disease (CVD) has been suggested in patients with systemic lupus erythematosus (SLE). The risk for myocardial infarction (MI), coronary artery disease and stroke has been reported as particularly prevalent in younger females compared with the reference population. This study was performed to analyse the standard incidence ratio (SIR) of and predict

A framework for list representation, enabling list stabilization through incorporation of gene exchangeabilities.

Analysis of multivariate data sets from, for example, microarray studies frequently results in lists of genes which are associated with some response of interest. The biological interpretation is often complicated by the statistical instability of the obtained gene lists, which may partly be due to the functional redundancy among genes, implying that multiple genes can play exchangeable roles in t

Context and disease when disease risk is low: the case of type 1 diabetes in Sweden

Background Several European studies have found significant small area variation in the risk of childhood onset (type 1) diabetes (T1D) which has been interpreted as evidence for contextual determinants of T1D. However, this conclusion may be fallacious since the limited number of newborn infants and the low risk for T1D is a source of spurious variability not properly handled by usual statistical

Larger tidal volume increases sevoflurane uptake in blood: a randomized clinical study

Background The rate of uptake of volatile anesthetics is dependent on alveolar concentration and ventilation, blood solubility and cardiac output. We wanted to determine whether increased tidal volume (V-T), with unchanged end-tidal carbon dioxide partial pressure (PETCO2), could affect the arterial concentration of sevoflurane. Methods Prospective, randomized, clinical study. ASA physical status

Lyme borreliosis: Clinical case definitions for diagnosis and management in Europe

P>Lyme borreliosis, caused by spirochaetes of the Borrelia burgdorferi genospecies complex, is the most commonly reported tick-borne infection in Europe and North America. The non-specific nature of many of its clinical manifestations presents a diagnostic challenge and concise case definitions are essential for its satisfactory management. Lyme borreliosis is very similar in Europe and North Amer

Prognostic and chemotherapy predictive value of gene-expression phenotypes in primary lung adenocarcinoma.

Purpose Primary lung adenocarcinoma remains a deadly disease. Gene expression phenotypes (GEPs) in adenocarcinoma have potential to provide clinically relevant disease stratification for improved prognosis and treatment prediction, given appropriate clinical and methodological validation. Experimental Design 2395 transcriptional adenocarcinoma profiles were assembled from 17 public cohorts and cla

The PLATO 2.0 mission

PLATO 2.0 has recently been selected for ESA's M3 launch opportunity (2022/24). Providing accurate key planet parameters (radius, mass, density and age) in statistical numbers, it addresses fundamental questions such as: How do planetary systems form and evolve? Are there other systems with planets like ours, including potentially habitable planets? The PLATO 2.0 instrument consists of 34 small ap