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Timber structures often combine multiple lateral load-resisting systems whose interaction under serviceability loading remains insufficiently understood. This study presents a full-scale experimental investigation into the lateral response of a single-storey timber mock-up comprising lightweight timber frame wall diaphragms, a roof diaphragm, and a centrally positioned moment-resisting frame. Two
Objective To examine associations of common mental disorders (CMDs) with lifestyle habits and cardiovascular risk factors among participants in targeted health dialogues in Sweden. Methods A cross-sectional study included 8903 40- and 50-year-olds between September 20, 2021, and January 10, 2024. CMDs included depressive, anxiety, and stress-related disorders. Associations between CMDs and lifesty
A B S T R A C T: In Sweden, the number of single women increased during the 19th century. Legal changes partly aimed at giving women more ways to earn a living were enacted, which gradually opened up the artisan trades to female entrants. By using establishment censuses, this paper examines how the number of women engaged in the artisan trades changed in four towns in southern Sweden during the se
Event classifiers are the most fundamental observables to probe the event topology of hadronic and nuclear collisions at relativistic energies. Over the last five decades, significant progress has been made to establish suitable event classifiers to probe different physics processes occurring in elementary (Formula presented) to heavy-ion collisions in a broad range of center of mass energies. One
Background: – Adverse muscle composition (AMC), defined by low muscle volume and increased muscle fat infiltration, has been associated with comorbidity and poor function in chronic kidney disease (CKD), and increased mortality in metabolic disorders and the general population. We investigated whether MRI-derived muscle composition is associated with all-cause mortality in a UK Biobank (UKB) imagi
Background: Homologous recombination (HR) deficiency (HRD) is prevalent in ovarian, prostate, and specific subgroups of breast cancer, particularly triple-negative breast cancer (TNBC). Tumor HRD status can be inferred through DNA-based, RNA-based, functional, or image-based approaches. A comprehensive evaluation of the concordance and discordance among HRD prediction methods derived from these di
Background and Objectives – Pyruvate dehydrogenase complex (PDHc) deficiency is a potentially treatable neurodegenerative genetic disorder. It represents a common cause of mitochondrial disease. Most published reports are limited to single cases, and population-based data are lacking. The objective of this study was to investigate the prevalence, incidence, and life expectancy and to explore genot
Background: Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and those with no or minimal brain injury may be identified before 72 h using novel methods. We present a protocol for the EARLY-NEURO study, which aims to evaluate whether good and poor ou
In ultra high-energy collisions, nuclei with very low binding energies are not expected to survive the dense and hot final state environment. The traditional view has therefore been that nuclei form via coalescence after the hot environment has dissipated. However, statistical thermal models, where hadrons are produced from a fireball at thermal equilibrium, can describe the relative abundances of
Semiconductors use built-in logic to perform test, validation, and other operational activities over the lifetime of the device. These test features, referred to as instruments, become a security risk, as they provide high observability and controllability of the device. The fear is that an adversary could exploit these instruments with malicious intent. We have analyzed and developed security mea
We present ON3R, an online-trained neural regressor addressing sparse-view structureless localization, where database images have limited visual overlap and no prebuilt 3D map. Given any sparse matches between a query and a K-tuple of posed database views, ON3R predicts 3D coordinates for matched query keypoints, supervised by database reprojection residuals and a monocular depth prior. Afterwards
This report describes and addresses patterns of discrimination in Sweden’s care sector, primarily related to gender and migrant status. It examines national legislation, collective agreements, case law, and equality bodies’ activities concerning equal treatment, pay transparency, parental leave, and occupational safety. It highlights the highly feminised nature of the care workforce, persistent ge
In this paper, we present a pipeline for visual localization using 2D-3D matching, yielding high localization accuracy comparable with hierarchical methods based on 2D-2D matching. This is accomplished through an active exploration strategy, which adaptively explores multiple parts of the scene to find the region that generates the most inlier matches, followed by refining the pose with a pose-to-
We present a general technique for efficient computation of second order information for optimization functionals involving many variables of different nature, frequently appearing in modern applications. This technique relies on the bilinear Hessian, and while the main tools for this task have been published elsewhere, we here focus on the problem of how to organize the computations in the multi-
Background and purpose: Routine collection of patient-reported outcome measures (PROMs) may provide valuable real-world data on quality of life (QoL) and treatment tolerability, complementing clinical outcomes. This study evaluated the feasibility of launching a semi-automated, department-wide PROM collection program at a large tertiary radiotherapy centre. Patients and methods: Patients ≥ 18 year
Background: Current research addressing recovery and everyday occupations among individuals with severe mental illness tends to focus on people of working age, whereas those aging with such conditions receive little attention. Whether younger and older users of mental health services differ regarding how they perceive their everyday occupations, personal recovery and quality of life seems unknown.
The development of techniques to culture and differentiate adult and pluripotent stem cells into diverse cell types over the past decades has sparked an increasing interest in the use of cells for organ regeneration. Such therapies aim to replace lost or damaged cells with functional ones. This can be achieved either through tissue engraftment of therapeutic cells or via their paracrine effects on
