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Background: Several neurotransmitters are expressed in the neurons of the trigeminal ganglion. One such signalling molecule is the pituitary adenylate cyclase-activating peptide (PACAP). PACAP signalling has been suggested to have a possible role in the pathophysiology of primary headaches. Objective: The present study was designed to investigate the relationship between PACAP and calcitonin gene-

Background: Lesions of the Ampulla of Vater are a rare condition and represent <10% of peri-ampullary neoplasms. Nevertheless, ampullary adenomas have the potential for malignant transformation to ampullary carcinomas by an adenoma-to-carcinoma sequence. Thus, adequate patient selection and complete resection (R0) of non-invasive ampullary lesions either by endoscopic papillectomy (EP), surgical a

Work hardening layer on and beneath the machined surface is one of the key factors that affects the performance and service time of the final component. However, the mechanism of the work hardening generation and its behavior are still great challenges and open issues to the academic and industry. In this paper, an investigation of the work hardening layer generated by chamfered tools is conducted

In a k-step adaptive linear multistep methods the coefficients depend on the k − 1 most recent step size ratios. In a similar way, both the actual and the estimated local error will depend on these step ratios. The classical error model has been the asymptotic model, chp+ 1y(p+ 1)(t), based on the constant step size analysis, where all past step sizes simultaneously go to zero. This does not refle

A handful of studies have investigated sexually antagonistic constraints on achieving sex-specific fitness optima, although exclusively through male-genome-limited evolution experiments. In this article, we established a female-limited X chromosome evolution experiment, where we used an X chromosome balancer to enforce the inheritance of the X through the matriline, thus removing exposure to male

Climate change is exposing high-latitude systems to warming and a shift towards more shrub-dominated plant communities, resulting in increased leaf-litter inputs at the soil surface, and more labile root-derived organic matter (OM) input in the soil profile. Labile OM can stimulate the mineralization of soil organic matter (SOM); a phenomenon termed “priming.” In N-poor subarctic soils, it is hypo

The purpose of the study is to identify and explore different applications of blockchain technology in supply chain management and suggest a framework for their analysis. The study addresses researchers' conflicting opinions regarding the hype of blockchain and clarifies which minor applications are hyped and which are currently more applicable. That helps supply chain practitioners appraise the d

Osteoblastoma is a locally aggressive tumour of bone. Until recently, its underlying genetic features were largely unknown. During the past two years, reports have demonstrated that acquired structural variations affect the transcription factor FOS in a high proportion of cases. These rearrangements modify the terminal exon of the gene and are believed to stabilise both the FOS transcript and the

Fine needle aspiration cytology (FNAC) is a widely accepted safe, simple and rapid diagnostic procedure used in the examination of neoplastic and non-neoplastic lesions of various locations. Since its introduction, FNAC has developed into an effective diagnostic tool practiced in a large majority of medical centres evaluating and treating oncological patients. The role of FNAC has been limited in

Cellular composition and morphology of components of photoreceptor apparatus of the retinae of camera eyes of some species of terrestrial gastropod pulmonate molluscs were studied and its evolutionary transformations were traced. It was demonstrated that all examined characteristics of photoreceptor apparatus of the most investigated species were normal for terrestrial pulmonates, while those of o

The energy intensive industry, producing basic materials, is responsible for 25 to 30% of today's global greenhouse gas emissions. The future supply of GHG neutral basic materials (e.g. steel, cement, aluminium, plastics, etc.) is a necessity for building a sustainable modern society. Deep decarbonisation of the energy intensive industries is technically possible but will require a major systemic The energy intensive industry, producing basic materials, is responsible for 25 to 30% of today's global greenhouse gas emissions. The future supply of GHG neutral basic materials (e.g. steel, cement, aluminium, plastics, etc.) is a necessity for building a sustainable modern society. Deep decarbonisation of the energy intensive industries is technically possible but will require a major systemic

The present report presents a conceptual assessment model or framework for policy relevant analysis of low carbon transitions. The aim of the study is not to present specific guidelines for how to design assessments of low carbon transitions, but rather to give food for thought on aspects that should be regarded in the design process. The exact design would then depend on the purpose of the assess

ObjectivesTo describe the process and results of the updated Swedish practice guidelines for monotherapy in epilepsy.Materials and MethodsThe Swedish Medical Products Agency led the process together with medical experts. Evidence rating in accordance with the International League Against Epilepsy (ILAE) template was linked to the Cochrane group's GRADE system. Evidence from recently published tria

Den återupptagna totalförsvarsplaneringen med syfte att öka beredskapen inför kriser och krig innebär ökade ansträngningar för många samhällsaktörer med olika roller, ansvar och uppgifter. Detta har aktualiserat behovet av ett förtydligat sektorsansvar.I denna rapport diskuteras vilka beståndsdelar ett sektorsansvar kan ha, med energisektorn som exempel, inklusive de styrningskedjor som kan använd

Russia has become a magnet for migrant workers from other post-Soviet countries, especially Central Asians. Although Russian business elites generally welcome this cheap labor source, the government has deferred to, and at times encouraged, xenophobic popular sentiment. Steadily tightening immigration rules have forced many foreign workers into the informal economy, where they are vulnerable to ex

This chapter explores the interconnections between informality, migrant agency and networks of trust and solidarity in hybrid political regimes. These processes will be illustrated through the comparative study of the Russian and Turkish migration regimes, specifically focusing on the case of Uzbek migrant workers and their patterns of residence, incorporation into the labour market, gendered expe