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From Fauna to Flames : Remote Sensing with Scheimpflug Lidar

This thesis presents applications of the Scheimpflug Lidar (S-Lidar) method. The technique has been applied to combustion diagnostics on a scale of several meters as well as fauna detection and monitoring over distances of kilometers. Lidar or laser radar is a remote sensing technique where backscattering of laser light is detected with range resolution along the direction of the laser beam. It is

The confluence of Cloud computing, 5G, and IoT in the Fog

In the wake of the arrival of cloud computing, future applications are poised to become more resilient and adaptive by embracing elasticity in an osmotic manner. Although cloud computing is a strong attractor for application developers, thereare still unconquered performance frontiers. Latency-sensitive and missioncritical applications make up a significant portion of all software systems, and the

Transitioning to Adulthood in Sweden: Comparing the Priorities of Immigrant Youths with Disabilities and Caregivers, from Middle-Eastern Countries

Background: There is limited knowledge about perceived challenges during the transition to adulthood among immigrant youths who are originally from Arabic-speaking countries but now residing in Sweden. Aim: The aim of this study was to describe self-identified problems encountered by immigrant youths with disabilities from Middle Eastern countries who were living in Sweden during their transition

Health-related quality of life in children with Type 1 diabetes: an RCT of hospital-based care and hospital-based home care at diagnosis

Introduction: When a child is diagnosed with Type 1 diabetes, it involves extensive lifestyle changes for the whole family. There is limited knowledge of the impact the initial care has for children and parents over time. The aim was to compare children’s diabetes-specific health-related quality of life (HRQOL) in hospital-based care and hospital-based home care (HBHC), 12 and 24 months after the

Rapid confocal imaging of vesicle-to-sponge phase droplet transition in dilute dispersions of the C 10 E 3 surfactant

The lamellar-to-sponge phase transition of fluorescently labelled large unilamellar vesicles (LUVs) of the non-ionic surfactant triethylene glycol mono n-decyl ether (C 10 E 3 ) was investigated in situ by confocal laser scanning microscopy (CLSM). Stable dispersions of micrometer-sized C 10 E 3 LUVs were prepared at 20 °C and quickly heated at different temperatures close to the lamellar-to-

Complex Interventions and Interorganisational Relationships: Examining Core Implementation Components of Assertive Community Treatment

Introduction: There is increasing interest in implementing evidence-based integrated models of care in community-based mental health service systems. Assertive Community Treatment (ACT) is seen as an attractive, and at the same time challenging, model to implement in sectored service settings. This study investigates the implementation process of such an initiative.Methods: Interviews were conduct

Association of IL1RAP-related genetic variation with cerebrospinal fluid concentration of Alzheimer-associated tau protein

A possible involvement of the gene IL1RAP (interleukin-1 receptor-associated protein) in the pathogenesis of Alzheimer’s disease (AD) has been suggested in GWASs of cerebrospinal fluid (CSF) tau levels and longitudinal change in brain amyloid burden. The aim of this study was to examine previously implicated genetic markers in and near IL1RAP in relation to AD risk, CSF tau and Aβ biomarkers, as

Crystal structure and substrate interactions of an unusual fungal non-CBM carrying GH26 endo-β-mannanase from Yunnania penicillata

Endo-β(1 → 4)-mannanases (endomannanases) catalyse degradation of β-mannans, an abundant class of plant polysaccharides. This study investigates structural features and substrate binding of YpenMan26A, a non-CBM carrying endomannanase from Yunnania penicillata. Structural and sequence comparisons to other fungal family GH26 endomannanases showed high sequence similarities and conserved binding res

Large Eddy Simulation and Experimental Analysis of Combustion Dynamics in a Gas Turbine Burner

Large eddy simulations (LES) and experiments (planar laser-induced fluorescence of the hydroxyl radical (OH-PLIF) and pressure transducer) have been carried out on a gas turbine burner fitted to an atmospheric combustion rig. This burner, from the Siemens SGT-800 gas turbine, is a low NOx, partially premixed burner, where preheat air temperature, flame temperature, and pressure drop across the bur

Analysis of RAMP3 gene polymorphism with body composition and bone density in young and elderly women

Background and aim: The Receptor Activity Modifying Proteins (RAMPs) are a group of accessory proteins, of which there are three in humans, that interact with a number of G-protein coupled receptors (GPCR) and play various roles in regulation of endocrine signaling. Studies in RAMP3 knockout (KO) mice reveal an age related phenotype with altered metabolic regulation and high bone mass. To translat

Computational homogenisation of thermo-viscoplastic composites : Large strain formulation and weak micro-periodicity

In this article, a first order two-scale finite element framework for fully coupled thermo-mechanical problems at finite deformations is considered. The scale bridging is achieved under application of Hill–Mandel condition based boundary conditions at the lower scale. Emphasis of the present article is on the extension of the concept of weak micro-periodicity to thermo-mechanically coupled problem

Invisible and Ignored : The Archaeology of Nineteenth-Century Subalterns in Sweden

This paper aims to discuss subalterns in different social environments in Sweden. The potential of archaeological studies of landless subalterns in rural and urban areas are shown though a number of case studies. It is argued that archaeology can show the multivocality of the lives of the subalterns, in the same way as it shows how the subalterns organized their daily life. This is done through th

Modeled aerosol-cloud indirect effects and processes based on an observed partially glaciated marine deep convective cloud case

A tropical maritime case of deep convective clouds was studied using a state-of-the-art aerosol-cloud model in order to evaluate the microphysical mechanisms of aerosol indirect effects (AIE). The aerosol-cloud scheme used is a hybrid bin/bulk model, which treats all phases of clouds and precipitation allowing a detailed analysis of process-level aerosol indirect effects on targeted cloud types.

Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates

AMP-activated protein kinase (AMPK) is a key regulator of cellular energy homeostasis, acting as a sensor of energy and nutrient status. As such, AMPK is considered a promising drug target for treatment of medical conditions particularly associated with metabolic dysfunctions. To better understand the downstream effectors and physiological consequences of AMPK activation, we have employed a chemic

Towards improved remote sensing based monitoring of dryland ecosystem functioning using sequential linear regression slopes (SeRGS)

We present a method for remote sensing based monitoring of changes in dryland ecosystem functioning based on the assumption that an altered vegetation rainfall relationship (VRR) indicates changes in vegetation biophysical processes, potentially leading to changes in ecosystem functioning. We describe the VRR through a linear regression between integrated rainfall and vegetation productivity (usin

Analysis of extinction and sustained ignition

The limiting conditions for sustained burning of materials are studied experimentally using gas burners. Small pool fire configurations are examined to determine the mass flux for a sustained surface diffusion flame (fire point) and the subsequent extinction limit of that flame. The burner results are compared to material data for sustained ignition, and are found to be lower. Material reported v

A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia

Diamond-Blackfan anemia (DBA) is a bone marrow failure syndrome caused by mutations in ribosomal protein genes. Pathogenic mechanisms are poorly understood but involve severely reduced proliferation of erythroid precursors. Because current DBA therapies are ineffective and associated with severe side effects, disease-specific therapies are urgently needed. We hypothesized that druggable molecular

Discrimination and policies of immigrant selection in liberal states

How should liberal societies select prospective members? A conventional reading of immigration history posits that whereas ascriptive characteristics drove immigration policy in the past, contemporary policy is based on the principle of nondiscrimination. Yet a closer look at the characteristics of those admitted reveals systematic group biases that run counter to liberalism’s core moral commitmen