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Fibrosis and the bladder, implications for function ICI-RS 2017

Aims: Most benign bladder pathologies are associated with an increase of extracellular matrix (ECM—fibrosis) and may progress from formation of stiffer matrix to a more compliant structure. The aims were to summarize current knowledge of the origins of bladder fibrosis and consequences in bladder function. Methods: A meeting at the International Consultation on Incontinence Research Society 2017 c

S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer’s Disease

Pro-inflammatory and amyloidogenic S100A9 protein is an important contributor to Alzheimer’s disease (AD) pathology. Traumatic brain injury (TBI) is viewed as a precursor state for AD. Here we have shown that S100A9-driven amyloid-neuroinflammatory cascade was initiated in TBI and may serve as a mechanistic link between TBI and AD. By analyzing the TBI and AD human brain tissues, we demonstrated t

Effektiva rättsmedel i EUs konkurrensrättsprocess

Abstract in Undetermined Under närmare ett decennium har jag följt behandlingen av AstraZenecas numera fastslagna överträdelser av konkurrensrätten. Den fällande domen är kanske inte alldeles oväntad, även om det funnits anledning att diskutera olika frågeställningar. När jag ser tillbaka på de samlade bidragen slår det mig att min främsta invändning är att myndigheterna så enögt främjar den gener

A trip to reach the target? : The labor supply of Swedish Baltic cod fishermen

This paper uses logbook data from Swedish Baltic Sea cod trawlers to investigate the revenue target hypothesis. Incomes from fishing can be highly variable and difficult to predict and it is possible that fishermen set specific revenue targets for their fishing trips to simplify decision making. In this paper a discrete choice stopping model is used where the fishermen must decide to stop or conti

Using panel survey and remote sensing data to explain yield gaps for maize in sub-Saharan Africa

The aim of this paper is to combine remote sensing data with geo-coded household survey data in order to measure the impact of different socio-economic and biophysical factors on maize yields. We use multilevel linear regression to model village mean maize yield per year as a function of NDVI, commercialization, pluriactivity and distance to market. We draw on seven years of panel data on African

What's in it for Africa? : European Union fishing access agreements and fishery exports from developing countries

Fishing access agreements have been widely criticized but there is little quantitative evidence of their effects on the economies of developing countries. The aim of this paper is to investigate the influence of the European Union’s fishing access agreements on 15 African countries’ fish exports to the OECD. More specifically, we investigate the effects on the extensive and intensive margins of tr

Landscape history confounds the ability of the NDVI to detect fine-scale variation in grassland communities

The NDVI is a remotely sensed vegetation index that is frequently used in ecological studies. There is, however, a lack of studies that evaluate the ability of the NDVI to detect fine-scale variation in grassland plant community composition and species richness. Ellenberg indicators characterize the environmental preferences of plant species—and community-mean Ellenberg values have been used to ex

Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification

Parkinson's disease (PD) is characterized by proteinaceous aggregates named Lewy Bodies and Lewy Neurites containing α-synuclein fibrils. The underlying aggregation mechanism of this protein is dominated by a secondary process at mildly acidic pH, as in endosomes and other organelles. This effect manifests as a strong acceleration of the aggregation in the presence of seeds and a weak dependence o

En ny social bostadspolitik? Nej, men en bra början.

S-rapporten, ”en ny social bostadspolitik” levererar en bra problemanalys och flera goda målbeskrivningar men deras förslag orkar inte helt i mål, menar Ingemar Bengtsson, Universitetslektor vid Avdelningen för Fastighetsvetenskap, Lunds Universitet. Ingemar Bengtsson ifrågasätter gruppens allmänna strävan att samhället ska öka den samlade bostadskonsumtionen och efterlyser i följande kommentar me

Den eleganta cyklisten : Cykling, mode och kvinnlighet i sekelskiftets svenska och danska damtidningar

The elegant cyclist: Cycling, fashion and femininity in Swedish and Danish women’s magazines at the turn of the 20th century.At the turn of the 20th century the new sport of cycling was endowed with femininity in Scandinavian ladies’ magazines. An analysis of the magazines Idun, Svensk Damtidning, Damernes Blad and Hjemmet between 1890 and the 1910s show that both Swedish and Danish magazines appe