To investigate epigenetic patterns associated with aneuploidy we used constitutional trisomy 8 mosaicism (CT8M) as a model, enabling analyses of single cell clones, harboring either trisomy or disomy 8, from the same patient; this circumvents any bias introduced by using cells from unrelated, healthy individuals as controls. We profiled gene and miRNA expression as well as genome-wide and promoter

Problem: Niche co-evolution deals simultaneously with the number and the character of species within a community. How can a community of predators and prey adaptively radiate to fill available niches? How many niches are there? And, can adaptive speciation at evolutionary branching points successfully fill the niches of the ESS? Model features: We use a predator–prey model with one fitness-genera

Abstract in UndeterminedInconel 718, an efficient superalloy for energy and aerospace applications, is currently machined with cemented carbide tools at low speed (vc≈60 m/min) due to its unfavorable mechanical and thermal properties. The article presents results of a study of superalloy machinability with whisker reinforced alumina, uncoated and coated PCBN tools. Turning of age hardened Inconel

Protein S functions as a cofactor for tissue factor pathway inhibitor (TFPI) and activated protein C (APC). The sex hormone binding globulin (SHBG)-like region of protein S, consisting of two laminin G-like domains (LG1 and LG2), contains the binding site for C4b-binding protein (C4BP) and TFPI. Furthermore, the LG-domains are essential for the TFPI-cofactor function and for expression of full APC

An integrated system for the production of hydrogen by gasification of biomass and electrolysis of water has been designed and cost estimated. The electrolyser provides part of the hydrogen product as well as the oxygen required for the oxygen blown gasifier. The production cost was estimated to 39 SEK/kg H-2 at an annual production rate of 15 000 ton, assuming 10% interest rate and an economic li

More than a decade ago we published a calculation of nuclear ground-state masses and deformations in Atomic Data and Nuclear Data Tables [P. Moller, J.R. Nix, W.D. Myers, W.J. Swiatecki, At. Data Nucl. Data Tables 59 (1995) 185]. In this study, triaxial nuclear shapes were not considered. We have now enhanced our model and studied the influence of triaxial shape degrees of freedom on the nuclear g

We report the clinical feasibility of fluoroscopic Roentgen stereophotogrammetric analysis (FRSA), a validated method to quantify, real time three-dimensional (3D) dynamic motion of stent grafts and the first clinical results after abdominal and thoracic endovascular repair (EVAR). Stent graft motion was measured at 30 (stereo) frames per second, during the cardiac cycle and in the patient after a

Objective To determine coverage and generalisability of data in the Swedish Biologics Register ARTIS. Methods Patients with adult onset rheumatoid arthritis (RA) were identified in the National Patient Register and the Swedish Rheumatology Quality Register, including the ARTIS cohort of patients exposed to biological agents. Exposure to etanercept and adalimumab between 2006 and 2008 was determine

I den här artikeln argumenterar jag för att vårt tänkande i grunden är metafor- och föreställningsstyrt. Bilder och konceptuella ramverk styr i mångt och mycket hur vi kommunicerar, och därmed i grunden argumenterar och debatterar. Jag hävdar att det finns en utbredd föreställning om att vårt tänkande är mer objektivt förankrat än vad det egentligen är. Som rättssociolog är min poäng att det även

Nystedt recently gave a combinatorial proof of the fact that Ore extensions are associative. As part of it he proves that two sets of strings are identical, using a counting argument. We show that the equality of the sets can be proven directly. (C) 2013 Elsevier B.V. All rights reserved.

Changing Landscapes and Persistent Places is a study of the cultural landscape on the Bjäre peninsula in northwest Skåne. The many Bronze Age remains that give the landscape its distinctive character are the starting point for an attempt to increase our understanding of the historical depth of today’s landscape. The two perspectives of “landscape” and “places” carry the discussion forward, almost

We present polarized-neutron diffraction measurements of the Ising-type spin-chain compound Ca3Co2O6 above and below the magnetic ordering temperature T-N. Below T-N, a clear evolution from a pure spin-density wave (SDW) structure to a mixture of SDW and commensurate antiferromagnet (CAFM) structures is observed on cooling. For a rapidly cooled sample, the majority phase at low temperature is the

BACKGROUND: Radiostereometric analysis (RSA) is often used for evaluating implanted devices over time. Following patients who have had tantalum beads implanted as markers in conjunction with joint replacements is important for longitudinal evaluation of these patients and for those with similar implants. As doing traditional RSA imaging is exacting and limited to specialized centers, it is import

Neutron reflectivity (NR) measurements have been performed on stimulus-responsive polymer brushes containing N-isopropylacrylamide (NIPAAM) at different temperatures and contrasts using two different brush samples of roughly the same grafting density and layer thickness. The NR data were analyzed using a novel method employing polymer density profiles predicted from lattice mean-field theory augme

By dissolving 30400kg of marine limestone in HCl and HF acid, our group has previously recovered common relict chromite grains (approximately 63250m) from ordinary chondritic micrometeorites that fell on ancient sea floors, up to 500Myr old. Here, we evaluate if CM group carbonaceous chondritic material, which makes up an important fraction of the micrometeorite flux today, contains analogous grai

Följande kapitel kommer att behandla avtalsrättens centrala generalklausul som gör det möjligt att jämka eller ogiltigförklara oskäliga avtalsvillkor. Paragrafen är omstridd och har tilldragit sig intresse då den öppnar upp för rättstillämparens skönsmässiga avgöranden – det inte finns några riktlinjer för vad som kan betecknas som oskäligt utöver den domstolspraxis som utvecklats. Det kan därmed