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Mixed pathologies of α-synuclein, β-amyloid and tau are relatively common in Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB). We therefore wanted to study the retention patterns of 18F-AV-1451 in PD, PD-dementia (PDD), and DLB. To do this 44 healthy controls, 11 non-demented patients with PD, 18 patients with PDD, and six patients with DLB underwent MRI and 18F-AV-1451 PET scanning an
Sulfite oxidase is a mononuclear molybdenum enzyme that oxidises sulfite to sulfate in many organisms, including man. Three different reaction mechanisms have been suggested, based on experimental and computational studies. Here, we study all three with combined quantum mechanical (QM) and molecular mechanical (QM/MM) methods, including calculations with large basis sets, very large QM regions (80
Politikens legitima parter bör ta avstånd från oetiska metoder, statuera goda exempel och redovisa en etik för digitalt kampanjande. Det kommer att främja valrörelsen, den öppna debatten och demokratin, skriver Jonas Andersson Schwarz, Stefan Larsson och Anders Mildner.
Increasing the turbine inlet temperature can enhance the thermal efficiency of a gas turbine. Therefore, modern gas turbines operate at a relatively high level of temperature and endure heavy thermal load. It is important to ensure the modern gas turbine works at a high performance and safe condition. Advanced cooling techniques are implemented in the gas turbine system. In the current study, effe
This work focuses into the combustion behaviour of single wheat straw particles with the aim of providing a quantitative description of the particle burning process from ignition to the early stages of the char oxidation. The single particles, in the size range 224–250 µm, were injected upward into a confined region with hot combustion products, produced by a flat flame McKenna burner, with a mean
A counter-flow reactor setup was designed to investigate the gas-phase sulfation and homogeneous nucleation of potassium salts. Gaseous KOH and KCl were introduced into the post-flame zone of a laminar flat flame. The hot flame products mixed in the counter-flow with cold N2, with or without addition of SO2. The aerosols formed in the flow were detected through Mie scattering of a 355 nm laser bea
Starch has undisputable importance in foods both from the nutritional—mainly energy—related‐and technological viewpoints. Different types of starch derivatives, including a number of hydrolysis products, are frequently used as food ingredients, especially because of the particular physicochemical properties they may confer. In recent years, certain hydrolytic derivatives of starch, such as maltode
The coexistence of ecologically similar species might be counteracted by ecological drift and demographic stochasticity, both of which erode local diversity. With niche differentiation, species can be maintained through performance trade-offs between environments, but trade-offs are difficult to invoke for species with similar ecological niches. Such similar species might then go locally extinct d
BACKGROUND: Pulses represent an important source of protein, as well as digestible and indigestible carbohydrates. Little information is available on the indigestible carbohydrates and antioxidant capacity of legume seeds. The cooked seeds of three pulses (black bean, chickpea and lentil) were evaluated for their indigestible fraction (IF), polyphenols content, antioxidant capacity and in vitro fe
Introduction: Glutathione (GSH) pathways play a key role the metabolism and elimination of the neurotoxicant methylmercury (MeHg). We hypothesized that maternal genetic variation linked to GSH pathways could influence MeHg concentrations in pregnant mothers and children and thereby also affect early life development. Methods: The GCLM (rs41303970, C/T), GCLC (rs761142, T/G) and GSTP1 (rs1695, A/G)
Kriminaliteten kan börja i 9-10årsoldern bland barn som inte klarar av skolans och vuxenvärldens krav
Banana, maize, potato and sagu starches were boiled in the presence or absence of plasticizer (glycerol), producing edible films. In vitro digestibility features, amylose content and amylopectin gel filtration behavior of films and parent starches were evaluated. Available starch contents were lower in glycerol-containing films, due to dilution by the plasticizer. Total resistant starch increased
The production of Z0 bosons at large rapidities in Pb–Pb collisions at sNN=5.02TeV is reported. Z0 candidates are reconstructed in the dimuon decay channel (Z0→μ+μ−), based on muons selected with pseudo-rapidity −4.0<η<−2.5 and pT>20GeV/c. The invariant yield and the nuclear modification factor, RAA, are presented as a function of rapidity and collision centrality. The value of RAA for the 0–20% c
Flaxseed has recently gained attention as a functional food, and the effect of adding flaxseed (10%, 15%, and 20%) to tortillas was evaluated. The physicochemical characteristics and the free fatty-acid (FFA) content of the oil extracted from flaxseed-added corn tortilla were determined. The results showed that the lipid (4.27%) and protein content (9.10%) of the control sample was statistically l
An account of the Stockholm Film Workshop (1973 - 2001) and how it became a site of film production by immigrant filmworkers, primarily from Latin America and Greece.
Induction hardening is a useful method for improving resistance to surface indentation, fatigue and wear that is favoured in comparison with through hardening, which may lack necessary toughness. The process itself involves fast heating by induction with subsequent quenching, creating a martensitic layer at the surface of the workpiece. In the present work, we demonstrate how to simulate the proce
How malleable are people's fairness ideals? Although fairness is an oft-invoked concept in allocation situations, it is still unclear whether and to what extent people's allocations reflect their fairness ideals. We investigate in a laboratory experiment whether people's fairness ideals are sensitive to spillover effects associated with the specific order of allocation tasks. Participants first ge
Three experiments on professional recruiters explored how applicants' ethnicity affects questions prepared for a job interview and the implications of this. Study 1 revealed that outgroup applicants prompt recruiters to focus more on whether applicants have integrated cultural norms and values fitting the ingroup norms (person-culture fit), as well as the match between the applicants and their wou
