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There is a clinical need for conceptually new treatments that target the excessive activation of inflammatory pathways during systemic infection. Thrombin-derived C-terminal peptides (TCPs) are endogenous anti-infective immunomodulators interfering with CD14-mediated TLR-dependent immune responses. Here we describe the development of a peptide-based compound for systemic use, sHVF18, expressing th
BackgroundOlder adults have a high prevalence of chronic pain, which can have a substantial effect on their health and quality of life. Patients’ use of effective pain relief methods is a central part of the treatment and management of chronic pain. The utilization of pain relief methods and their perceived effectiveness are important knowledge for treating and managing chronic pain for clinicians
Serial dependence (SD) refers to the effect in which a person’s current perceptual judgment is attracted toward recent stimulus history. Perceptual and memory processes, as well as response and decisional biases, are thought to contribute to SD effects. The current study examined the processing stages of SD facial identity effects in the context of task-related decision processes and how such effe
BACKGROUND: Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and total-tau protein (tau) are novel blood biomarkers of neurological injury, and may be used to predict outcomes in critical COVID-19.METHODS: A prospective multicentre cohort study of 117 consecutive and critically ill COVID-19 patients in six intensive care units (ICUs) in southern Sweden between May and Novem
Membrane processes are widely used for desalination and wastewater treatment worldwide. In this presentation we will review some interesting membrane concepts which are either currently used or are under development. The initial focus will be on drinking water preparation from lake and river water and desalination of brackish water which are well established in Sweden. Furthermore, new will be pre
IntroductionThe pulp and paper sector is a key global industry. Presently, pulp mills prioritize the production of pulp, fibers, and electricity. By transforming traditional pulp mills into lignocellulosic biorefineries, they can become a key element of a future, circular bioeconomy. To accomplish this, pulp mills need to close their loops and optimize the use of the lignocellulosic feedstock, not
Proteins are important for our daily diet and thus, one of the most important food ingredients. Currently, the global protein market was valued at over 72 billion U.S. dollars and is projected to reach 114.6 billion U.S. dollars by 2030. The success story of membranes in the food sector is closely tied to their ability to effectively recover proteins.A milestone for the adoption of membrane techno
The European project ‘REsilient WAter Innovation for Smart Economy’ (REWAISE) aims to establish a novel ‘smart water ecosystem’ by integrating an advanced digital infrastructure for decentralized water services and decision-making, engaging all stakeholders to highlight the actual value of water. The approach will reduce the consumption of freshwater and energy while also recovering valuable nutri
The utilization of membrane technology in the food industry is directly tied to its success in protein recovery processes. Membrane technology was first introduced in the food industry for the extraction of proteins from whey, a by-product of cheese production that was difficult to dispose of due to its low solids content and high biological oxygen demand. By using ultrafiltration, whey proteins w
Time domain reflectometry (TDR) has been proven to take accurate readings of the apparent dielectricconstant Ka and bulk electrical conductivity σa. These measurements have been used for estimations ofwater content (θ) and concentration of different chemicals. The concentration of an ionic pollutant ortracer can be estimated from the soil solution electrical conductivity σw. Several different cali
This deliverable focuses on capturing the current status of testing and validation of services from the RI’s and ENVRI-Hub itself, that are both exposed to EOSC. This means that services are in scope that are shared via the ENVRI Catalogue of Services to the EOSC marketplace. The EOSC validation activities will check the readiness of the ENVRI-FAIR services at the sub-domain and cluster level for
The overarching goal of ENVRI-FAIR is for all participating ENVRIs to improve their FAIRness and prepare the connection of their data repositories and services to the European Open Science Cloud (EOSC). With the development of FAIR implementations from the participating RIs and integrated services among the environmental subdomains, these data and services will be brought together at a higher leve
During the firstyear of the project the cluster worked on the data service requirement tracking and a technology landscape and gap analysis on the RI FAIR data/services level, to provide an up-to-date investigation of the most common gaps the ENVRIs need to bridge with respect to the FAIR principles and the EOSC requirements. The FAIRness analysis (D5.1) established that the participating RIs disp
In this fascinating biography of the Indian revolutionary M. P. T. Acharya (1887–1954), Ole Birk Laursen uncovers the remarkable transnational networks, movements and activities of India’s most important anticolonial anarchist in the twentieth century.Driven by the urge for complete freedom from colonialism, authoritarianism, fascism and militarism, which are rooted in the idea and politics of the
D5.5 “Guidelines for validation of ENVRI-FAIR services” formulates the criteria and test plan for validating the overall quality of the ENVRI-FAIR services and summarises the guidelines for testing and validating the functionality of the services developed in WP8-WP11 in synergy with WP7. The criteria will allow the developers of the ENVRI data services to validate the results towards the EOSC cat
Narratives of the Indian revolutionary movement in exile have often focused on abstract notions of ‘London’—with a particular focus on ‘India House’ in Highgate—or ‘Paris’ without taking into account specific geographies of Indian anti-colonialism within these imperial metropoles. Drawing on addresses provided in intelligence reports, this article takes a spatial approach and explores how particul
