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Hormonal influences in migraine — interactions of oestrogen, oxytocin and CGRP

Migraine is ranked as the second highest cause of disability worldwide and the first among women aged 15–49 years. Overall, the incidence of migraine is threefold higher among women than men, though the frequency and severity of attacks varies during puberty, the menstrual cycle, pregnancy, the postpartum period and menopause. Reproductive hormones are clearly a key influence in the susceptibility

Accuracy of magnetic resonance imaging staging of tumour and nodal stage in rectal cancer treated by primary surgery : a population-based study

Aim: The preoperative stage of rectal cancer is an important prognostic factor affecting treatment recommendations. Currently, magnetic resonance imaging (MRI) is used for clinical staging to identify patients who should be recommended for neoadjuvant oncological treatment. The aim of this work was to investigate the accuracy of the preoperative T- and N-stage and also involvement of the mesorecta

Luminescence of ODC(II) in quartz and cristobalite glasses

The results of the optical spectroscopy of twofold coordinated silicon centers – ODC(II) in quartz and cristobalite glasses are presented. The luminescence and excitation spectra attributed to different local symmetry of ODC(II) were investigated under synchrotron excitation in the VUV region. The observed differences in the luminescence and excitation spectra of ODC(II) are caused by the environmThe results of the optical spectroscopy of twofold coordinated silicon centers – ODC(II) in quartz and cristobalite glasses are presented. The luminescence and excitation spectra attributed to different local symmetry of ODC(II) were investigated under synchrotron excitation in the VUV region. The observed differences in the luminescence and excitation spectra of ODC(II) are caused by the environm

Skin Exposures, Hand Eczema and Facial Skin Disease in Healthcare Workers During the COVID-19 Pandemic: A Cross-sectional Study

The COVID-19 pandemic has led to enhanced hygiene procedures and use of personal protective equipment, but also to increased attention to occupational skin disease in healthcare workers. The occurrence of hand and facial skin disease in > 5,000 Swedish healthcare workers was investigated in a questionnaire survey. Levels of skin exposure related to hygiene procedures and personal protective equipm

Guiding migrating salmonid smolts : Experimentally assessing the performance of angled and inclined screens with varying gap widths

The loss of longitudinal connectivity in regulated rivers, both up- and downstream, has been detrimental for biodiversity worldwide. While progress has been made regarding upstream fish passage solutions, many questions remain unanswered regarding downstream passage alternatives. To address these knowledge gaps, we used Atlantic salmon (S. salar) smolts to experimentally assess the guidance effici

A review of studies assessing ecosystem services provided by urban green and blue infrastructure

Urban green and blue infrastructure (GBI) and associated ecosystem services (ES) are increasingly recognized for their potential to address urban sustainability challenges. This has resulted in an increase in studies quantifying ES in cities. In this review, we analysed 850 peer-reviewed publications to characterize urban ES assessment in terms of geographical location, urban GBI type and methodol

Let’s talk about communication in strategic communication; : an analysis of students’ understanding of strategic communication and its implications

The aim of this paper is to address the importance of communication theory for the understanding of strategic communication. Underlying this focus are the debates and discussions on the definition of strategic communication, which have primarily been occupied with the meaning of the concept strategic. The definition and meaning of communication tend to be implicit or undefined and Van Ruler (2018)

In governments we trust : Enacting trust in Finnish and Swedish state-owned enterprises

The Swedish and Finnish states are significant owners of enterprises. In both countries, the results for the state-owned enterprises (SOE) are compiled into an annual report presented to the Parliament. It is a way to report on financial performance as well as a way to build trust and legitimize state ownership. The document is thus a meeting point and place of negotiation foreconomic and politica

Pronominal case in Västerbottnian

In this article, I consider the use of seemingly old nominative forms (ONF) in object position. The phenomenon is noted for the dialects of Västerbotten (in Northern Sweden) by several authors. Earlier works imply that the phenomenon is rather recent (early 1900s) and that the phenomenon is in more common usage in the inland rural areas than by the more urban coast. I discuss the structural analysIn this article, I consider the use of seemingly old nominative forms (ONF) in object position. The phenomenon is noted for the dialects of Västerbotten (in Northern Sweden) by several authors. Earlier works imply that the phenomenon is rather recent (early 1900s) and that the phenomenon is in more common usage in the inland rural areas than by the more urban coast. I discuss the structural analys

De novo DHDDS variants cause a neurodevelopmental and neurodegenerative disorder with myoclonus

Subcellular membrane systems are highly enriched in dolichol, whose role in organelle homeostasis and endosomal-lysosomal pathway remains largely unclear besides being involved in protein glycosylation. DHDDS encodes for the catalytic subunit (DHDDS) of the enzyme cis-prenyltransferase (cis-PTase), involved in dolichol biosynthesis and dolichol-dependent protein glycosylation in the endoplasmic re

COG8 deficiency causes new congenital disorder of glycosylation type IIh

We describe a new Type II congenital disorder of glycosylation (CDG-II) caused by mutations in the conserved oligomeric Golgi (COG) complex gene, COG8. The patient has severe psychomotor retardation, seizures, failure to thrive and intolerance to wheat and dairy products. Analysis of serum transferrin and total serum N-glycans showed normal addition of one sialic acid, but severe deficiency in sub

Intracranial hemorrhage as the initial manifestation of a congenital disorder of glycosylation

Intracranial hemorrhage in a term neonate is a rare event in the absence of an identifiable precipitating factor such as severe thrombocytopenia, mechanical trauma, asphyxia, infections, or congenital vascular malformations. Congenital disorders of glycosylation are a genetically and clinically heterogeneous group of multisystem disorders characterized by the abnormal glycosylation of a number of