Filetype
PURPOSE OF REVIEW: This review aims to give an overview of recent advances in the clinical management of children <18 years of age with end-stage pulmonary hypertension refractory to conventional medical therapy.RECENT FINDINGS/SUMMARY: The increased awareness and characterization of pediatric pulmonary vascular disease has amounted more data toward creating an accurate, and comprehensive, risk pr
This study tests the viability of multiple sorting tasks (MST) as a method to explore perceptions of public space and its potential for people that are vulnerable to loneliness. The procedure integrates qualitative and quantitative aspects and obviates the challenge of people articulating how they interact with their surroundings, especially being aware of what features of their environment are in
Urban streets are an integral part of the public realm. Streets are commonly planned following normative design principles focused on the connectivity of road networks and urban morphology. Beyond their function as mobility infrastructure, streetscapes’ aesthetic, social, and cultural qualities also have an important impact on the experience of the overall urban environment and human well-being. T
Fistulizing perianal Crohn’s disease is complex and negatively affects quality of life. Rectal advancement flap (AF) has been widely adopted as a sphincter-preserving procedure for treating complex anal fistulas. The European Crohn’s and Colitis Organisation (ECCO) guidelines on surgical treatment of Crohn’s disease state that AF is a therapeutic option for patients with Crohn’s disease and comple
In the Multiple Sorting Task (MST) participants sort entities into their self-defined categories. The descriptions they provide of their categories provide qualitative data. Multi-dimensional scaling of sorting generates quantitative results. Relating the qualitative descriptions to the quantitative output creates integrated mixed methods. As part of the study of conceptions of public space an onl
BackgroundObesity is commonly diagnosed using BMI, which does not capture total adiposity or fat distribution, as highlighted by the recent Lancet D&E Commission report. We assessed the prognostic value of an adiposity-based classification combining body fat percentage (BF%) and waist circumference (WC) in relation to cardiometabolic and kidney outcomes and evaluated its concordance with BMI.M
Drawing on ethnographic observations in Sweden and affect theory, this study immerses researcher-consumer bodies in extended retail spaces to explore affective encounters. Conceptualizing consumption spaces as affective assemblages, it unveils how affective states of disposition, disorientation, and distress from interactions with socio-material elements shape bodily experiences of inclusion and e
BACKGROUND: CFTR modulators, including Elexacaftor/Tezacaftor/Ivacaftor (ETI), have markedly improved clinical outcomes for people with cystic fibrosis (pwCF), but the molecular impact on airway inflammation remains incompletely understood. This study aimed to characterise longitudinal changes in airway inflammation and sputum proteomes following ETI treatment.METHODS: Sputum from pwCF (n = 30) wa
Real catalysts consisting of nanoparticles host many nanofacets. Each nanofacet changes its structure and function in response to its local environment but is also affected by neighboring nanofacets. Time-resolved operando experiments close to realistic conditions at polycrystals mimicking real catalyst particles are unfortunately challenging but could be highly rewarding. Here, we demonstrate how
Context: Life satisfaction (LS) is associated with health and longevity but decreases after spinal cord injury (SCI). Yet, little is known about changes in LS over time, many years after SCI. Objectives: To assess changes in LS over six years among older adults aging with long-term SCI, determine how changes in LS are associated with sex, age, injury characteristics, and with changes in secondary
Artikeln analyserar hur Århuskonventionens tredje pelare om allmänhetens tillgång till rättslig prövning har implementerats i svensk rätt och därefter utvecklats genom EU‑domstolens praxis och svenska domstolsavgöranden. Analysen exemplifierar genom att ta sin utgångspunkt i miljöorganisationers talerätt i skogsbruksfrågor. Lagstiftarens ursprungliga intentioner vid införlivandet (särskilt Ds 200
