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Cancer patients responded better to immunotherapy and had a better prognosis if their melanoma tumours contained specific clusters of B cells, according to new research from Lund University in Sweden. The study is published in Nature. B cells linked to effective cancer immunotherapyCancer patients responded better to immunotherapy and had a better prognosis if their melanoma tumours contained spec

https://www.lucc.lu.se/article/b-cells-linked-effective-cancer-immunotherapy - 2025-10-03

In a major study of hereditary breast cancer, a global network of researchers (including some from Lund University) has identified over 350 faults in DNA that increase an individual’s risk of developing the disease. The researchers believe that these faults can affect as many as 190 genes. Published in Nature Genetics, a scientific journal, the results are said to be the thus far most comprehensiv

https://www.lucc.lu.se/article/major-study-gives-most-comprehensive-map-breast-cancer-risk - 2025-10-03

In their quest to find new and better methods to make cancer cells more susceptible to treatment, Karin Lindkvist and her research group at Lund University in Sweden are looking into the world of molecules, using the X-rays at the MAX IV laboratory. The researchers believe that limiting the cells' access to sugar will make cancer cells more sensitive to treatment. Karin Lindkvist in the laboratory

https://www.lucc.lu.se/article/researchers-believe-sugar-and-obesity-can-make-cancer-cells-more-difficult-kill - 2025-10-03

In recent years, RNA molecules, with the ability to affect or turn off pathogenic genes, have become promising drug candidates in several areas. However, it has been a challenge to develop techniques to deliver the RNA molecules into the cells where they have an effect. Researchers at Lund University in Sweden have now developed a sensitive technique that makes it possible to study the delivery in

https://www.lucc.lu.se/article/rna-drugs-one-step-closer-be-being-used-cancer-treatment - 2025-10-03

By preventing sugar uptake, researchers succeeded in increasing the cancer cells’ sensitivity to chemotherapeutic treatment. The studies, led by researchers at Lund University in Sweden, were carried out on cancer cells in a lab environment. The results were recently published in the research journal Haematologica. Just like the body’s cells, cancer cells need energy like the sugar molecule, gluco

https://www.lucc.lu.se/article/starved-cancer-cells-became-more-sensitive-chemotherapy - 2025-10-03

A new way of identifying cancer biomarkers has been developed by researchers at Lund University in Sweden. The new technology allows very sensitive, quick and cost-effective identification of cancer biomarkers. The research is published in Nature Communications Biology. Today, every third person will get cancer in their lifetime, and the current trend suggests that in a few years that number will

https://www.lucc.lu.se/article/novel-biomarker-technology-cancer-diagnostics - 2025-10-03

A new and promising approach for treatment of lung cancer has been developed by researchers at Lund University. The treatment combines a novel surgical approach with smart nanoparticles to specifically target lung tumors. The new study has been published in the July issue of Advanced Therapeutics. Lung tumors are often difficult to remove using current surgical techniques due to their location in

https://www.lucc.lu.se/article/new-promising-treatment-uses-smart-nanoparticles-target-lung-cancer - 2025-10-03

A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer. PDE5 inhibitors include a few approved drugs in which sildenafil (Viagra) is the most well-known. The article is published in Nature Communications. “Available preclinical eviden

https://www.lucc.lu.se/article/potency-enhancing-drugs-linked-decreased-risks-men-colorectal-cancer - 2025-10-03

Emma Hammarlund was one of six researchers from Lund University in Sweden that was granted five-year starting grants from the European Research Council. Emma Hammarlund, geobiologist and researcher at the Division of Translational Cancer Research, will investigate how life could develop on our planet. The availability of oxygen has long been the prime focus for different hypotheses, however resear

https://www.lucc.lu.se/article/lucc-researcher-receive-erc-starting-grant - 2025-10-03

Researchers at Lund University in Sweden have developed a computational model which is effective in detecting and identifying genetic mutations in breast tumours. The study, the largest of its kind in the world, includes results from over 3 200 patients with breast cancer. The researchers used RNA sequencing, a sensitive, precise tool which has very gradually started to be applied clinically, alth

https://www.lucc.lu.se/article/new-analytical-model-detects-mutations-breast-cancer - 2025-10-03

A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine. Every year, about 800 children in the US are diagnosed with neuroblastoma, an aggressive cancer of the nervous system that most frequently arises in the adrenal glands

https://www.lucc.lu.se/article/promising-treatment-aggressive-childhood-cancer - 2025-10-03

Markel has worked in the field of botulinum neurotoxins (BoNTs) during his PhD in Pål Stenmark's team, using X-ray crystallography and cryo-EM to solve the structure of several proteins related to the botulinum neurotoxins. His main cryo-EM project consisted in structural work on the 300 kDa complex of the novel BoNT serotype X and its partner protein NTNH. He has been trained as an internal user

https://www.microscopy.lu.se/article/markel-martinez - 2025-10-03

I work as a researcher at the Faculty of Medicine studying protein-protein complexes arising at the host-pathogen interface, with the aim of understanding how pathogens evade the human immune defence. The main methods we are using are quantitative and structural mass spectrometry (cross-linking and hydrogen-deuterium exchange) in combination with single-particle cryo-EM. Since its start in 2018, I

https://www.microscopy.lu.se/article/lotta-happonen-short-biography - 2025-10-03

Derek Logan's research group is based at the Dept. of Biochemistry and Structural Biology at Lund University. His research focuses on the elucidation of structure-function relationships in proteins and their complexes. A particular focus is on allosteric regulation of the essential enzyme ribonucleotide reductase and drug design against the medically important galectin family of proteins. The prin

https://www.microscopy.lu.se/article/derek-logan-short-biography - 2025-10-03

Prof. Stenmark leads a research team at EMV, Lund university. He focuses on structure-based drug design, both in the development of small molecule drugs targeting cancer and in the engineering of protein drugs (e.g. neurotoxins). The main methods used are X-ray crystallography and single particle cryo-EM.

https://www.microscopy.lu.se/article/pal-stenmark-short-biography - 2025-10-03

Prof. Wallenberg is leading a group in solid state chemistry/nanoscience engineering at the Chemistry Institution, LU, with characterisation of structure and chemical composition of materials down to the atomic level as a special topic.  Materials range from inorganic compunds to  semiconductors to biological structures. He is the director of nCHREM, the national center for high-resolution electro

https://www.microscopy.lu.se/article/reine-wallenberg-short-biography - 2025-10-03

Anna Carnerup is in charge of maintaining and operating the 200 kV cryo-TEM at nCHREM. She has a PhD in Physical Chemistry and has many years of experience  of plunge-freezing and investigating solutions of water-lipid-protein systems in the cryo-TEM. 

https://www.microscopy.lu.se/article/anna-carnerup-short-biography - 2025-10-03

A course for PhD students with a background in physics. Starting in January the course is intended for students with a background in physics or similar.This 7.5 hp course focuses on hard X-ray interaction with matter. The topics covered include:X-ray sourcesScattering and absorptionRefraction and reflection from interfaces, refractive indexX-ray opticsScattering from non-crystalline material, smal

https://www.microscopy.lu.se/article/modern-x-ray-physics-diffraction-and-imaging - 2025-10-03

Meet Carl Troein, new co-worker at CIPA since June 2020. Carl has a background in physics and computational biology and is a 2D spectroscopy analysis expert. Can you tell us about your role at CIPA?Certainly! I've been recruited to help researchers working with spectroscopic 2D imaging. In particular, I am focusing on developing methods and tools for processing vibrational spectroscopy data, inclu

https://www.microscopy.lu.se/article/hello-there - 2025-10-03

On 20-21 September 2024, the OSCE Academy conducted its annual Alumni Conference on the theme of “Economic Development of Central Asia” featuring three panels: Anti-Corruption, Green Economy and Digital Economy. During two days, participants discussed regional corruption issues and anti-corruption policies, sustainable economic practices, environmental stewardship, and addressed the way digitaliza

https://www.mocca.lu.se/article/economic-development-central-asia-alumni-conference-osce-academy-bishkek - 2025-10-03