Human midbrain organoids grown in silk recapitulate midbrain development and support functionally mature dopamine neurons
In their latest study, published in Nature Communications, the Parmar Lab has established midbrain organoids using silk microfibers as scaffolds, offering a refined in vitro model of human midbrain development. They have studied their silk midbrain organoids using single cell sequencing, proteomics and functional assessment in order to shed light on the developmental trajectory, maturation and sub