Published 2 October 2018 The islets of Langerhans in the pancreas contain not only insulin-producing cells, but also four other hormone-producing cell types. Using a new method, researchers are to study their interaction by mapping previously unknown genetic networks. “It will give us new possibilities to direct medicines at new targets”, says associate professor Nils Wierup who will present the f

https://www.ludc.lu.se/article/mapping-mechanisms-behind-type-2-diabetes - 2025-08-13

Published 2 October 2018 Tord Ajanki started diabetesportalen.se just over a decade ago. Now he is to relinquish the editorship and retire. “It feels strange, good in one way, but it’s difficult to stop doing something that you have been involved in for so long”, he says. Tord Ajanki initially trained as a nurse.  “My wife and I wanted to save the world! We were going to do the training and work a

https://www.ludc.lu.se/article/father-diabetesportalense-retires - 2025-08-13

Published 5 October 2018 The complement proteins that circulate in our blood are an important part of our immune system. They help identify bacteria, viruses and other harmful organisms, making it easier for our white blood cells to find and neutralise dangerous microbes. Researchers at Lund University in Sweden have now discovered a previously unknown function of the central complement protein, C

https://www.ludc.lu.se/article/new-function-key-component-immune-system-discovered - 2025-08-13

Published 3 October 2018 The TEDDY Study has increased our knowledge about what happens prior to the onset of autoimmune diabetes (type 1 diabetes) and has shown that a stomach infection can trigger coeliac disease. Lund University in Sweden has now received just over SEK 40 million from the American National Institutes of Health (NIH) to continue the TEDDY Study for another five years. “We have l

https://www.ludc.lu.se/article/international-diabetes-study-receives-sek-40-million-continue - 2025-08-13

Published 8 October 2018 Can insulin absorbed in small doses through food in early childhood get the immune system accustomed to insulin and thereby delay – or prevent – type 1 diabetes? Researchers hope to find the answer through POInT, a study starting in Skåne this autumn. Newborn babies in Skåne with a high risk of autoimmune diabetes (type 1 diabetes) can take part in the study. The infants f

https://www.ludc.lu.se/article/new-study-babies-skane-prevent-type-1-diabetes - 2025-08-13

Published 8 October 2018 By blocking a protein, VDAC1, in the insulin-producing beta cells, it is possible to restore their normal function in case of type 2 diabetes. In preclinical experiments, the researchers behind a new study have also shown that it is possible to prevent the development of the disease. The findings are published in the scientific journal Cell Metabolism. The researchers at L

https://www.ludc.lu.se/article/new-discovery-restores-insulin-cell-function-type-2-diabetes - 2025-08-13

Published 26 October 2018 In the so far largest clinical study of the development of microbiomes, i.e. intestinal flora, in infants, researchers at the Baylor College of Medicine, USA, have found that development takes place in different phases that can be associated with lifestyle changes during the early stages in life. The findings are based on samples from the TEDDY study and are published in

https://www.ludc.lu.se/article/new-findings-intestinal-flora-development-infants - 2025-08-13

Published 20 December 2018 On November 30th a well-attended seminar rocusing on issues needed to consider already at an early stage when developing e-Health solutions was organized by LUDC Innovation Office, the Department of Clinical Sciences Malmö, and Medeon Science Park. Patrik Midlöv presented some examples of e-Health studies performed at the Medical Faculty.Henrik Ahlén, e-Health Strategist

https://www.ludc.lu.se/article/e-health-what-needed-research-reach-clinical-benefit - 2025-08-13

Published 15 January 2019 How far has precision medicine come? What challenges are we facing within clinical and translational research? See the seminar on metabolic research in retrospect. (Most of the lectures are held in Swedish) Precision medicine: a global overviewPaul Franks, professor, Lund University Diabetes CentreIn English Precision medicine: a global overview Vilka är utmaningarna för

https://www.ludc.lu.se/article/metabolic-research-today-and-beyond - 2025-08-13

Published 21 January 2019 Registration is now open for The Smooth Muscle Conference, taking place July 14-19, 2019, in West Palm Beach, Florida. Organized by Chairs Jonathan Jaggar, PhD, University of Tennessee; and Maria Gomez, PhD, Lund University, with support from the Federation of American Societies for Experimental Biology (FASEB), this conference is highly interactive and brings together an

https://www.ludc.lu.se/article/register-now-faseb-science-research-conference-src-smooth-muscle-conference - 2025-08-13

Published 29 January 2019 What do muffins and space travel have in common? Answer: They affect our genes through altered DNA methylation patterns. Two researchers who studied this recently met at the public defence of a doctoral thesis at Lund University. Andrew Feinberg from Johns Hopkins University's School of Medicine in Baltimore, USA, has often been called the Andrew Feinberg from Johns Hopki

https://www.ludc.lu.se/article/big-data-muffins-and-space-travel - 2025-08-13

Published 1 June 2009 Eric Lander, a long time collaborator of the diabetes researchers at LUDC, has been appointed as scientific advisor to Barack Obama, the new president of the United States. Eric Lander is an honorary doctor at the faculty of medicine at Lund University and member of the Scientific Advisory Board of LUDC. - It’s an honor, of course, but it's more the responsibility to serve ri

https://www.ludc.lu.se/article/ludc-and-president-obama-have-same-scientific-advisor - 2025-08-13

Published 1 June 2009 350 international top scientists are gathering in Malmö to attend the 10th international congress of the Immunology of Diabetes Society (IDS). The focus of the congress will be on how to prevent and cure type 1 diabetes. -Malmö hosting such an event underlines Lund University Diabetes Centre’s (LUDC) position at the absolute scientific front. Not least when it comes to clinic

https://www.ludc.lu.se/article/international-scientific-congress-type-1-diabetes - 2025-08-13

Published 1 June 2009 In competition with about ten other European consortia, Lund University and collaborators have received a research grant of approximately 150 million SEK. The money, which is given by the European Union, will be complemented by funding from the pharmaceutical industry. The funding will be used to advance in the battle against complications caused by diabetic diseases. In addi

https://www.ludc.lu.se/article/unified-european-effort-fight-diabetic-complicati - 2025-08-13

Published 4 August 2009 A common variant of the melatonin receptor gene increases the risk of developing type 2 diabetes. This discovery was made by two research groups at Lund University Diabetes Centre (LUDC), and reveals a completely new mechanism underlying diabetes. The finding, presented in the latest issue of the scientific journal Nature Genetics, also opens a new avenue for treating the d

https://www.ludc.lu.se/article/unexpected-link-between-diabetes-and-sleep-hormone-melatonin - 2025-08-13

Published 6 July 2009 Heart attack and stroke afflicts many in spite of them having few or no known risk factors such as high blood pressure, diabetes, changes in blood fat or smoking. -Because of this it is important to be able to identify those at risk who would benefit from preventive treatment, says Olle Melander, docent at Lund University and chief physician at Akutcentrum, UMAS. He is the ma

https://www.ludc.lu.se/article/new-risk-markers-discovered-cardiac-infarction-and-stroke - 2025-08-13

Published 10 September 2009 The risk of becoming obese is 2.5 times higher for those who have double copies of the best known risk gene for overweight and obesity. However, this is only true if the fat consumption is high. A low fat diet neutralizes the harmful effects of the gene. “This means that the critical factor is what you eat. At least in the case of the FTO gene, the most important obesit

https://www.ludc.lu.se/article/food-habits-are-more-important-most-important-obesity-risk-gene - 2025-08-13

Published 7 October 2009 Type 2 diabetes is often not caused by a lack of insulin per se, but an inability of the beta cells to secrete adequate amounts of it. Recently, scientists at LUDC have identified a previously unknown agent that plays an important role in the release of insulin. Knock-out mice that lack the ClC3 protein have a severely diminished capacity to secrete insulin in spite of int

https://www.ludc.lu.se/article/happy-insulin-cell-needs-be-sour - 2025-08-13

Published 11 December 2009 Children participating in the DiPiS and TEDDY studies, who are at high risk of developing type 1 diabetes, have the possibility to receive GAD vaccine. The hope is that this will stop the process and prevent the children from falling ill. Some of the children who have an increased risk of type 1 diabetes start producing antibodies directed at the insulin producing cells.

https://www.ludc.lu.se/article/vaccine-offered-children-i-skania-sweden-high-risk-diabetes - 2025-08-13

Published 23 November 2009 The finding of a new genetic risk variant and the description of the exact underlying mechanism explains, on a molecular level, the connection between stress and diabetes. This scientific breakthrough is published online today in the journal Science. Carriers of the risk variant have stressed insulin producing cells which greatly reduces their ability to secrete insulin.

https://www.ludc.lu.se/article/risk-gene-activates-stress-system-and-increases-risk-diabetes - 2025-08-13