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Largest ever TauPET study of Alzheimer’s deepens understanding of the disease

In a study led by Lund University and the Amsterdam University Medical Center, researchers used PET to analyse aggregates of tau pathology in more than 12,000 people from all over the world. The study – the largest ever of its kind – examines the connection between genetic predisposition, gender and age in relation to tau pathology in Alzheimer’s disease. The study is published in Nature Neuroscie

https://www.multipark.lu.se/article/largest-ever-taupet-study-alzheimers-deepens-understanding-disease - 2025-11-23

MultiPark scientists awarded prestigious VR consolidator grant

With an approval rate of just 17 %, this year’s Swedish Research Council grants were harder than usual to secure. Still, several of MultiPark’s group leaders were awarded major grants in Medicine and Health 2025. Receiving grants from the Swedish Research Council is seen as a mark of quality and an important step in advancing an independent research group. Recently, five MultiPark researchers were

https://www.multipark.lu.se/article/multipark-scientists-awarded-prestigious-vr-consolidator-grant - 2025-11-23

The unexpected way we might one day diagnose Alzheimer’s

How do you stop Alzheimer’s disease without a simple way to diagnose it? It’s a real chicken and egg problem, as I wrote last year on TGN. Discovering a treatment for Alzheimer’s requires lots of clinical trials for new drugs—but it’s difficult to enroll participants without a way to identify people who have the disease early enough for potential treatments to work. Read the full article here

https://www.multipark.lu.se/article/unexpected-way-we-might-one-day-diagnose-alzheimers - 2025-11-23

More evidence that blood tests can detect the risk of Alzheimer’s

A new study confirms that a simple blood test can reveal whether there is accelerating nerve cell damage in the brain. The researchers analysed neurofilament light protein (NFL) in blood samples from patients with Alzheimer’s disease. Recently published in JAMA Neurology, the study suggests that the NFL concentration in the blood could be able to indicate if a drug actually affects the loss of ner

https://www.multipark.lu.se/article/more-evidence-blood-tests-can-detect-risk-alzheimers - 2025-11-23

Researchers block protein that plays a key role in Alzheimer’s disease

In recent years, it has become increasingly clear to researchers that the protein galectin-3 is involved in inflammatory diseases in the brain. A study led by researchers at Lund University in Sweden now shows the de facto key role played by the protein in Alzheimer’s disease. When the researchers shut off the gene that produces this protein in mice, the amount of Alzheimer’s plaque and the inflam

https://www.multipark.lu.se/article/researchers-block-protein-plays-key-role-alzheimers-disease - 2025-11-23

Minerva award to Tomas Deierborg

The Future Faculty is proud to present the 2019 Minerva Award to Tomas Deierborg, associate professor at the Department of Experimental Medical Sciences.The Minerva award selection committee's motivation for the choice is: "The core values of the Minerva award are honesty, trust, fairness, respect, responsibility and courage. From the nominations it is obvious that Tomas Deierborg possess all thes

https://www.multipark.lu.se/article/minerva-award-tomas-deierborg - 2025-11-23

Drawing Closer: Alzheimer’s Blood Test for Primary Care

In today’s JAMA Neurology, researchers led by Oskar Hansson, Lund University, Sweden, report how a fully automated immunoassay for plasma Aβ performed when they put it through its paces. Roche Diagnostic’s Elecsys system predicted Aβ-positive individuals with about 80 percent accuracy. That number improved by 5 percent when the researchers took ApoE genotype into consideration. Alzforum first repo

https://www.multipark.lu.se/article/drawing-closer-alzheimers-blood-test-primary-care - 2025-11-23

New PET Staging Scheme for Amyloid?

Scientists are becoming more nuanced in how they use amyloid scans—not just to detect the presence of Alzheimer’s pathology, but also to pinpoint disease stage. At this year’s Alzheimer’s Association International Conference, held July 13–18 in Los Angeles, researchers led by Niklas Mattsson and Oskar Hansson at Lund University, Sweden, debuted a new staging scheme. Read the full article here

https://www.multipark.lu.se/article/new-pet-staging-scheme-amyloid - 2025-11-23

Parkinson Skåne visits BMC

On October 30, MultiPark arranged, in collaboration with the Parkinson Skåne patient organization and Studieförbundet Vuxenskolan, a half-day study visit for the public to the Biomedical Center. Professor Angela Cenci Nilsson led the event and guided the audience through the afternoon.       The chair of Parkinson Skåne gave a brief presentation of their organization, followed by talks by two pers

https://www.multipark.lu.se/article/parkinson-skane-visits-bmc - 2025-11-23

Skiers had lower incidence of depression and vascular dementia – but not Alzheimer’s

Half as many diagnosed with depression, a delayed manifestation of Parkinson’s, a reduced risk of developing vascular dementia - but not Alzheimer’s. These connections were discovered by researchers when they compared 200 000 people who had participated in a long-distance cross-country ski race between 1989 and 2010 with a matched cohort of the general population. The results of the population reg

https://www.multipark.lu.se/article/skiers-had-lower-incidence-depression-and-vascular-dementia-not-alzheimers - 2025-11-23

High-tech method for uniquely targeted gene therapy developed

Neuroscientists at Lund University in Sweden have developed a new technology that engineers the shell of a virus to deliver gene therapy to the exact cell type in the body that needs to be treated. The researchers believe that the new technology can be likened to dramatically accelerating evolution from millions of years to weeks.Read the full article here

https://www.multipark.lu.se/article/high-tech-method-uniquely-targeted-gene-therapy-developed - 2025-11-23

New imaging method sheds light on Alzheimer's disease

To understand what happens in the brain when Alzheimer's disease develops, researchers need to be able to study the molecular structures in the neurons affected by Alzheimer's disease. Researchers at Lund University in Sweden have tested a new imaging method for this purpose. The research is published in the journal Advanced Science.Read the full article here

https://www.multipark.lu.se/article/new-imaging-method-sheds-light-alzheimers-disease - 2025-11-23

New method provides unique insight into the development of the human brain

Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With this new insight, researchers hope to be able to produce different types of neural cells for the treatment of neurologica

https://www.multipark.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-11-23

How toxic protein spreads in Alzheimer’s disease

Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau.Read the full article here

https://www.multipark.lu.se/article/how-toxic-protein-spreads-alzheimers-disease - 2025-11-23

Message from the coordinator

From the coordinator:As we approach Midsommar, we in MultiPark can reflect on the extraordinary last few months and hope that our environment can return back more to meetings, seminars and productive exchanges after the summer. Although neurodegenerative diseases were less in the news because of Covid-19, people with Parkinson and Alzheimer’s diseases were however more affected by the virus. Our w

https://www.multipark.lu.se/article/message-coordinator - 2025-11-23

New research paves way for developing therapies that could slow down Alzheimer´s

Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer’s disease pathology. The study has been published in Stem Cell Reports.Read the full article here.See also interview with Alzheimerfonden regarding the study. 

https://www.multipark.lu.se/article/new-research-paves-way-developing-therapies-could-slow-down-alzheimers - 2025-11-23