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Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain

Excess weight gain throughout adulthood can lead to adverse clinical outcomes and are influenced by complex factors that are difficult to measure in free-living individuals. Metabolite profiling offers an opportunity to systematically discover new predictors for weight gain that are relatively easy to measure compared to traditional approaches. New publication in PLOS ONE

https://www.lupop.lu.se/article/using-metabolite-profiling-construct-and-validate-metabolite-risk-score-predicting-future-weight - 2025-11-29

Daily School Physical Activity from before to after Puberty Improves Bone Mass and a Musculoskeletal Composite Risk Score for Fracture

This 7.5-year prospective controlled exercise intervention study assessed if daily school physical activity (PA), from before to after puberty, improved musculoskeletal traits. There were 63 boys and 34 girls in the intervention group (40 min PA/day), and 26 boys and 17 girls in the control group (60 min PA/week). We measured musculoskeletal traits at the start and end of the study. The overall mu

https://www.lupop.lu.se/article/daily-school-physical-activity-after-puberty-improves-bone-mass-and-musculoskeletal-composite-risk - 2025-11-29

Diabetes mellitus as a risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden

Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential associations between DM, C

https://www.lupop.lu.se/article/diabetes-mellitus-risk-factor-compression-neuropathy-longitudinal-cohort-study-southern-sweden - 2025-11-29

Injuries and illnesses in Swedish Paralympic athletes—A 52‐week prospective study of incidence and risk factors

Sports‐related injuries and illnesses in Paralympic sport (SRIIPS) are a concern, but knowledge about the etiology and risk factors is limited. The aim of this study was to describe the annual incidence, type, and severity of injuries and illnesses among Swedish Paralympic athletes and to assess risk factors. New publication in Scandinavian Journal of Medicine & Science in Sports

https://www.lupop.lu.se/article/injuries-and-illnesses-swedish-paralympic-athletes-52-week-prospective-study-incidence-and-risk - 2025-11-29

Changes in breast density over serial mammograms: A case-control study

In addition to a breast density category, temporal changes in breast density have gained attention as a dynamic breast cancer risk marker. This case-control study aimed to investigate a potential change in breast density preceding tumor development and the relationship of this potential change to prognostic pathological tumor variables. New publication in European Journal of Radiology

https://www.lupop.lu.se/article/changes-breast-density-over-serial-mammograms-case-control-study - 2025-11-29

Social Stratification, Diet Diversity and Malnutrition among Preschoolers: A Survey of Addis Ababa, Ethiopia

In Sub-Saharan Africa, being overweight in childhood is rapidly rising while stunting is still remaining at unacceptable levels. A key contributor to this double burden of malnutrition is dietary changes associated with nutrition transition. Although the importance of socio-economic drivers is known, there is limited knowledge about their stratification and relative importance to diet and to diffe

https://www.lupop.lu.se/article/social-stratification-diet-diversity-and-malnutrition-among-preschoolers-survey-addis-ababa-ethiopia - 2025-11-29

The role of professional logics in quality register use: a realist evaluation

Clinical practice improvements based on quality-register data are influenced by multiple factors. Although there is agreement that information from quality registers is valuable for quality improvement, practical ways of organising register use have been notoriously difficult to realise. The present study sought to investigate the mechanisms that lead various clinicians to use quality registers fo

https://www.lupop.lu.se/article/role-professional-logics-quality-register-use-realist-evaluation-0 - 2025-11-29

Women with fair phenotypes seem to confer a survival advantage in a low UV milieu. A nested matched case control study

Sun exposure in combination with skin pigmentation is the main determinant for vitamin D status. Human skin color seems to be adapted and optimized for regional sun ultraviolet (UV) intensity. However, we do not know if fair, UV-sensitive skin is a survival advantage in regions with low UV radiation. New publication in PLOS ONE

https://www.lupop.lu.se/article/women-fair-phenotypes-seem-confer-survival-advantage-low-uv-milieu-nested-matched-case-control-study - 2025-11-29

Establishing spatially-enabled health registry systems using implicit spatial data pools: case study – Uganda

Spatial epidemiological analyses primarily depend on spatially-indexed medical records. Some countries have devised ways of capturing patient-specific spatial details using ZIP codes, postcodes or personal numbers, which are geocoded. However, for most resource-constrained African countries, the absence of a means to capture patient resident location as well as inexistence of spatial data infrastr

https://www.lupop.lu.se/article/establishing-spatially-enabled-health-registry-systems-using-implicit-spatial-data-pools-case-study-0 - 2025-11-29

Consumption of red meat, genetic susceptibility, and risk of LADA and type 2 diabetes

Analyses were based on Swedish case–control data comprising incident cases of LADA (n = 465) and T2D (n = 1528) with matched, population-based controls (n = 1789; n = 1553 in genetic analyses). Multivariable-adjusted ORs in relation to self-reported processed and unprocessed red meat intake were estimated by conditional logistic regression models. Attributable proportion (AP) due to interaction wa

https://www.lupop.lu.se/article/consumption-red-meat-genetic-susceptibility-and-risk-lada-and-type-2-diabetes - 2025-11-29

Transplanterade celler avslöjar tidiga tecken på typ 1-diabetes

När typ 1-diabetes diagnostiseras är ofta de flesta insulinproducerande betacellerna redan förstörda. Med en egenutvecklad transplantationsteknik har forskare vid Karolinska Institutet och University of Miami Miller School of Medicine kunnat upptäcka tidiga tecken på sjukdomen hos möss och på så vis sätta in tidig behandling för att rädda betacellerna. Studien publiceras i Diabetologia, det Europe

https://www.diabetesportalen.lu.se/artikel/transplanterade-celler-avslojar-tidiga-tecken-pa-typ-1-diabetes - 2025-11-29

Region Skåne satsar på diabetesvården

Som ett av tre områden tilldelas sektion diabetologi vid Skånes universitetssjukhus utmärkelsen ”Centre of Excellence - in Health”. För att stärka kopplingen mellan sjukvård och forskning inrättas nu ett nytt kliniskt-metabolt centrum på CRC i Malmö. - Att Region Skåne gör en sådan här satsning är en stark signal till alla som jobbar inom diabetesområdet i Malmö/Lund, som kliniker, forskare eller

https://www.diabetesportalen.lu.se/artikel/region-skane-satsar-pa-diabetesvarden - 2025-11-29

Varierande kvalitet för kontinuerlig blodsockermätning

Kontinuerlig blodsockermätning är en sensor under huden som ger patienten information om sockernivån och varnar för låga och höga blodsockervärden. Men de tekniska lösningar som erbjuds på marknaden skiljer sig stort både vad gäller noggrannhet och användarvänlighet. Forskare vid Sahlgrenska akademin, Göteborgs universitet, har tillsammans med forskare i USA i en klinisk prövning jämfört säkerhete

https://www.diabetesportalen.lu.se/artikel/varierande-kvalitet-kontinuerlig-blodsockermatning - 2025-11-29

Kvinnor med högt blodtryck får inte samma behandling som män

Kvinnor som behandlas för högt blodtryck får inte samma läkemedel som män. Kvinnor når inte heller behandlingsmålen lika ofta som män. Kvinnor med diabetes får mer sällan den rekommenderade behandlingen för högt blodtryck. Det visar en avhandling vid Sahlgrenska akademin som studerat över 40 000 patienter. Ungefär en tredjedel av Sveriges vuxna befolkning drabbas någon gång av högt blodtryck. Hos

https://www.diabetesportalen.lu.se/artikel/kvinnor-med-hogt-blodtryck-far-inte-samma-behandling-som-man - 2025-11-29

På cykel mellan Barcelona och Wien

På femton dagar cyklade Josefin Palmén med en grupp andra träningsentusiaster från Barcelona till Wien. Målet var diabeteskonferensen EASD. - Nästa år ska vi cykla från Wien till Stockholm. Bilder från racet på mHealth Grand tours hemsida ser ut att vara tagna från musikalsuccén “Sound of music”. Den som läser Josefin Palméns blogg förstår dock att upplevelsen inte är lika romantisk.Cykelracet gjo

https://www.diabetesportalen.lu.se/artikel/pa-cykel-mellan-barcelona-och-wien - 2025-11-29

Forskning om träning och fett prisas

Tina Rönn, forskare vid Lunds universitets Diabetescentrum har utsetts till mottagare av “Carl Ludwig Award” som delas ut av the Scandinavian Physiological Society i samarbete medtidsskriften Acta Physiologica. Priset får hon för sin vetenskapliga artikel "Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a 6-month

https://www.diabetesportalen.lu.se/artikel/forskning-om-traning-och-fett-prisas - 2025-11-29

Diabeteskväll 13 oktober i Lund

När? Måndagen den 13 oktober 2014, kl 18.00–20.30Var? Aulan i Blocket, plan 1, Entrégatan 7, Skånes universitetssjukhus i Lund.Program:18.00–18.10 Introduktion till kvällens föreläsningar.Hindrik Mulder, professor, Lunds universitets Diabetescentrum.18.10–18.40 Fetmakirurgins märkligt goda effekter vid typ 2-diabetes.Nils Wierup, forskare, Lunds universitets Diabetescentrum.18.40–19.10 En helt ny

https://www.diabetesportalen.lu.se/artikel/diabeteskvall-13-oktober-i-lund - 2025-11-29

Nya rön om hur insulinfrisättningen hämmas vid typ 2-diabetes

Nya forskningsresultat om hur fettsyran palmitinsyra hämmar insulinfrisättning skapar förutsättningar för utvecklingen av nya och bättre diabetesläkemedel. Den nya studien från forskare vid Uppsala universitet publiceras nu i den vetenskapliga tidskriften Diabetes. Typ 2-diabetes kännetecknas av rubbad ämnesomsättning. Förutom förhöjda blodsockernivåer ses ökade koncentrationer av fettsyror tidigt

https://www.diabetesportalen.lu.se/artikel/nya-ron-om-hur-insulinfrisattningen-hammas-vid-typ-2-diabetes - 2025-11-29