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Adrenoleukodystrophy (ALD) is an X-linked recessive disease caused by defects in the ABCD1 gene, leading to the accumulation of very long-chain fatty acids in the nervous system, adrenalglands, blood and other tissues. Male ALD patients may present with either the severe neurologicalphenotype of cerebral ALD, characterized by inflammatory demyelination in the white matter and rapid neurological de
