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Introduction: Vitamin D deficiency has previously been shown to be associated with cancer-related fatigue. If vitamin D deficiency affects fatigue in frail elderly has not been studied before. The aim of this study was to investigate associations between vitamin D, fatigue, frailty, and sarcopenia in frail elderly with cancer (FEC) and without cancer (FE) in comparison with healthy controls. Metho

The experimental realization of quantum molecular spectroscopy with entangled photons remains challenging owing to the low signal-to-noise ratio resulting from the use of low-flux entangled photons. High-flux entangled photons via intense entangled beams can be used to improve the signal-to-noise ratio, but the presence of unentangled photons contaminates the quantum signal stemming from entangled

This paper explores regenerative building production as an approach that goes beyond minimising environmental harm to actively generating net-positive socio-ecological impacts. Grounding the discussion in sustainability transitions theory, we highlight how construction significantly contributes to global carbon emissions and waste. Using the phenomena construction methodology, a conceptual framewo

Susceptibility testing of clinical multidrug-resistant (MDR) and reference P. aeruginosa strains was performed using the standard twofold serial dilution method. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of antiseptics were determined. MIC and MBC values were also interpreted as the bacteriostatic index of antiseptic activity (BSIAA) and the bactericid

Den här boken ger en introduktion till straffrättens påföljdssystem. Framställningen omfattar både det regelverk som gäller och de sammanhang som påverkar påföljdsbestämningen: straffprocessen, de principer och värden som bär upp systemet, frågor om straffets funktion och rättfärdigande samt den historiska utvecklingen av påföljdssystemet. Förutom att presentera påföljdsbestämningens övergripande

Directed movement is fundamental to animal behavior, yet the mechanisms underlying robust orientation remainincompletely understood. The ball-rolling dung beetle offers a unique model system for investigating these mechanismsdue to its distinctive navigational challenges: maintaining a straight-line trajectory while moving backwardand transporting a dung ball. In this thesis, I investigates orient

Introduction Parkinson’s disease (PD) is a common neurodegenerative disease, which has extensive pathology that critically includes the loss of midbrain dopaminergic neurons. This loss leads to debilitating motor features such as bradykinesia and rigidity, as well as some non-motor symptoms. Intracerebral dopamine cell transplants have been explored for many years as a new approach to treating PD

Importance Women with adverse pregnancy outcomes have higher subsequent cardiovascular risks, but their long-term risk of atrial fibrillation (AF) and potential causality are unclear. A better understanding of such risks is needed to identify women with high risk early in life and guide interventions to prevent AF and its complications. Objective To determine long-term risks of AF associated with

A water-based sol–gel strategy driven by boron coordination enables the direct fabrication of transparent, photoactive TiO2 films under ambient conditions. Mixing ammonium oxo-lactato titanate with boric acid produces non-fluidic gels that dry into amorphous TiO2 films containing rutile-like domains.

Oligodendrocyte precursor cells (OPCs) display functional plasticity beyond myelination. Kuwata et al. explore how hypoxia shapes OPC features after ischemic stroke. Combining single-cell transcriptomics with in vivo and ex vivo models, they reveal oxygen-dependent OPC phenotypes promoting angiogenesis and remyelination, highlighting OPC versatility and potential for novel stroke cell therapies.

We propose a new class of high-rate spatially coupled LDPC (SC-LDPC) codes based on the convolutional selforthogonal codes (CSOCs) first introduced by Massey. The SCLDPC codes are constructed by treating the irregular graph corresponding to the parity-check matrix of a systematic rate R=(n-1) / n CSOC as a convolutional protograph. The protograph can then be lifted using permutation matrices to ge

Aducanumab, a human IgG1 antibody with plaque-clearing effects and modest clinical benefit, binds selectively to aggregated Aβ via the N-terminal region. Yet, the molecular details of how the antibody engages Aβ1-42 fibrils remain unresolved. Using magic-angle spinning NMR, we show that binding of aducanumab preserves the overall architecture of the Aβ1-42 fibril core while inducing significant st

Following regulatory approval of anti-amyloid beta (Aβ) therapies, a better characterization of patients receiving these treatments is needed to guide clinical management and inclusion in future trials. This Alzheimer's Association-convened workgroup proposes a terminology, treatment-related amyloid clearance (TRAC), to reflect alterations in disease pathophysiology based on biomarker evidence for

Background: Distal pancreatic resection is associated with a high frequency of postoperative complications. The aim of this study was to characterize the effect of diabetes mellitus (DM) on short-term complications after distal pancreatectomy. Methods: Patients who underwent distal pancreatectomy between 1 January 2010 and 31 December 2020 were identified from the Swedish National Pancreatic and P

Dynamic task offloading is essential for real-time robotic applications, enabling them to adapt to fluctuating computational demands and maintain efficiency under changing conditions. This paper introduces a dynamic task offloading framework that incorporates monitoring, decision making, offloading triggering, and performance monitoring to optimize resource usage by offloading real-time tasks to e

Background: Incisional hernia remains the most common complication of open abdominal surgery. The aim was to investigate whether a reinforced tension-line suture combined with standard 4: 1 small-bite closure reduces the 3-year incidence of computed tomography-detected incisional hernia in open colorectal cancer surgery. Methods: Patients aged > 18 years, scheduled for colorectal cancer resection