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Telomerase reverse transcriptase (TERT) activity is up-regulated in several types of tumors including glioblastoma (GBM). In the present study, 128 primary glioblastoma patients were examined for single nucleotide polymorphisms of TERT in blood and in 92 cases for TERT promoter mutations in tumors. TERT promoter mutations were observed in 86% of the tumors and of these, C228T (-124 bp upstream sta
Brief User-Controlled Admission (BUCA) refers to a set of crisis interventions in which the traditional gatekeeping role of the physician is bypassed, allowing service users to independently decide when to access short-term inpatient care through a pre-negotiated agreement. Examples include Brief Admission by self-referral, Patient-Initiated Brief Admission, Patient-Controlled Admission, and Self-
Predicting live birth after the first IVF/ICSI treatment is challenging, as many factors may interactto affect IVF/ICSI outcomes. Adenomyosis is one factor that impacts live birth rates. Machinelearning algorithms have been shown valuable for detecting complex dependencies and predictingoutcomes in different clinical settings. We aimed to develop a prediction model for live birth afterIVF/ICSI trePredicting live birth after the first IVF/ICSI treatment is challenging, as many factors may interact to affect IVF/ICSI outcomes. Adenomyosis is one factor that impacts live birth rates. Machine learning algorithms have been shown valuable for detecting complex dependencies and predicting outcomes in different clinical settings. We aimed to develop a prediction model for live birth after IVF/ICSI
BACKGROUND: Digital technologies are increasingly central to supporting autonomy, health, and social participation in later life. However, disparities persist in the ability to keep up with technological developments, affecting individuals' opportunities to benefit from digital health and social innovations.OBJECTIVE: This study aimed to investigate factors associated with individuals' self-report
BackgroundResearch involving current and future generations of older adults in the design of smart home technology (SHT) is scarce. In this study, current and future generations of older adults, professionals, and researchers together sought to identify user needs and aspirations for and related to SHT. The aim was to co-produce prioritized ideas for SHT solutions to support engagement in everyday
The orbital area contains a variety of anatomical structures including the eyelids, tarsal conjunctiva, caruncle, lacrimal gland, lacrimal drainage system, skin, skin adnexa, and soft tissues. It is surrounded by bone and cartilaginous structures and is highly vascularized and interspersed by the cranial nerves. This complex of neighboring, highly specialized tissues results in a large spectrum of
BACKGROUND: Dupuytren disease (DD) is a benign fibroproliferative disorder affecting the hand. Although diabetes mellitus is a known risk factor, the underlying mechanisms behind this association remain unclear. This study aimed to examine the relationship between glycemic control and DD in type 1 (T1D) and type 2 diabetes (T2D), and to identify other metabolic risk factors influencing DD risk.MET
Due to the complex anatomy of the mediastinum and its proximity to a number of organs, a variety of neoplastic and nonneoplastic lesions may occur in the mediastinum. The majority of these are accessible via fine-needle aspiration cytology (FNAC). The main indication for FNA in the mediastinum is to distinguish between neoplasm and nonneoplastic conditions and between benign and malignant neoplasm
Cytological examination of specimens obtained from bronchial tree and lung tissue is a cost-effective, safe, and fast method of diagnosing lung disease. There are many established sampling and preparation techniques, producing cytological specimens for routine microscopic examinations, and a spectrum of ancillary methods such as microbiology, cytochemical, immunocytochemical, and molecular genetic
Sammanfattning Titel: Prognostisk mogenhet inom organisationen Seminariedatum: 2026-01-15 Kurs: FEKH38 Författare: Linus Beck, Gabriel Fogwall, Jack Grenter Handledare: Magnus Johansson Nyckelord: Efterfrågeprognostisering, Prognostisk mognad, Prognostik, Organisatoriska kapabiliteter, Beslutsfattande. Forskningsfrågor: Hur kan prognostisk mognad förklaras med hjälp av organisatoriska, analytiska
Fine-needle aspiration cytology (FNAC) has been widely used as a tool to obtain specimens for the morphological diagnosis of numerous lesions in a variety of locations for more than 80 years. In many clinical situations, FNAC can render a definitive diagnosis either from aspiration smears alone using well-defined cytological criteria or from smears combined with clinical data, radiological finding
This richly illustrated book will help presurgically diagnose pediatric/young adult tumors. The content is divided into two parts. The first part shows step-by-step how to perform a small volume specimen such as fine needle aspiration/core needle biopsy and how to correlate the morphology with the clinical, radiological, and/or molecular information. In turn, the second part presents a comprehensi
The main indication for cytologic study of the liver is the evaluation of mass-forming lesions, either symptomatic or incidentally discovered. Recent major progress in imaging methods is shifting the spectrum of cytologic diagnostics toward smaller lesions, which are often challenging. The convenience of relatively easy fine-needle aspiration (FNA) procedures with high diagnostic accuracy and low
