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Structure of murine complement component C3. II. Nucleotide sequence of cloned complementary DNA coding for the alpha chain

From the inserts of two recombinant plasmids isolated from a murine liver cDNA library, the nucleotide sequence coding for the C3 alpha chain was obtained and the corresponding amino acid sequence was derived. The alpha chain portion of the mRNA is 2979 nucleotides long, specifying a polypeptide of 993 amino acids. The molecular weight of the alpha chain, in the absence of carbohydrate, was calcul

A fair path to the future? - foundations for empirical research

Looking ahead, the quest for environmental sustainability may turn out to be the most important political challenge of the twenty-first century. Though consensus is growing about some of the policy objectives like climate stability, political attitudes to these issues remain highly contested. Political parties seem to differ on both ontological assessments (how severe are the problems) and remedia

Attention and tool-use in the evolution of language

It is argued that the capacity to focus attention is crucial for intentional communication. Intentional communication is goal-intended; directed at changing mental states and as a consequence behaviour; about a referential object common to sender and recipient; and about objects that may be context-and referent-independent. Three different kinds of attention is discerned: scanning, attention attra

Generalisation Methods for Propagating Updates between Cartographic Data Sets

Automation is increasingly important in producing and maintaining cartographic data sets. This thesis deals with automatic methods to propagate updates between cartographic data sets. The major idea is to update only the most detailed data set (master data set) and then propagate these updates automatically to less detailed data sets (target data sets). The approach used is firstly to formulate li

A 0.7 - 3.7 GHz Six Phase Receiver Front-End With Third Order Harmonic Rejection

This paper presents a highly linear receiver frontend operating from 700 MHz to 3.7 GHz with 3rd order harmonic rejection. It consists of a complementary low noise transconductance amplifier with capacitive cross coupling and negative gm current sources, a six phase current-mode passive mixer, and baseband transimpedance amplifiers providing programmable gain. The circuit has been fabricated in 65