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uKNIT: Breaking Round-alignment for Cipher Design : Featuring uKNIT-BC, an Ultra Low-Latency Block Cipher

Automated cryptanalysis has seen a lot of attraction and success in the past decade, leading to new distinguishers or key-recovery attacks against various ciphers. We argue that the improved efficiency and usability of these new tools have been undervalued, especially for design processes. In this article, we break for the first time the classical iterative design paradigm for symmetric-key primit

Schizophrenia in children, adults and older people with intellectual disability compared with the general population: a Swedish register study (IDcare)

BACKGROUND: The knowledge about the prevalence of schizophrenia among people with intellectual disabilities (ID) is sparse, particularly concerning the distribution in different age groups.AIMS: To investigate the prevalence of diagnoses in the schizophrenia spectrum among people with ID compared with the general population (gPop).METHODS: This was an 8-year longitudinal register study. The partic

Men's Attitudes Towards Participation in Organised Prostate Cancer Testing: An Abductive Thematic Analysis

Background and objectiveOrganised prostate cancer (PCa) testing (OPT) was introduced in Sweden to gain knowledge in preparation for a potential national PCa screening programme. This study aims to explore men’s opinions regarding the OPT invitation letters and the attitudes influencing their decision to participate in or decline OPT.MethodsWe conducted semi-structured telephone interviews with 30

Reliability of Variables of Consonant Production and Velopharyngeal Competence in 10-year-olds with Cleft Palate Using Multiple Raters

Objective: To assess the reliability of speech data and speech-related quality indicators in the Swedish quality registry for cleft lip and palate (CLP) at 10 years of age. Design: Retrospective study. Setting: University hospitals. Participants: One hundred twenty-one 10-year-olds with unilateral or bilateral CLP. Main outcome measures: Six independent raters reassessed audio recordings for compa

A Validation of the Swedish Colorectal Cancer Register – With Focus on Histopathology, Complications and Recurrences

Background: There is an urgent need to evaluate the quality of healthcare systems to improve and deliver high-quality care. Clinical registries have become important platforms for performance measurements, improvements, and clinical research. Hence, the quality of data in registries is crucial. This study aimed to assess the validity of data in the Swedish Colorectal Cancer Register (SCRCR). Metho

Detecting Stubborn Behaviors in Influence Networks : A Model-Based Approach for Resilient Analysis

The wide spread of on-line social networks poses new challenges in information environment and cybersecurity. A key issue is detecting stubborn behaviors to identify leaders and influencers for marketing purposes, or extremists and automatic bots as potential threats. Existing literature typically relies on known network topology and extensive centrality measures computation. However, the size of

Preserving white privileges in organizations : white fragility, white counterreactions, and institutional resistance

Racialized inequalities in organizations and workplaces are reproduced not only by the discrimination of non-whites but also by behaviors among whites aimed at counteracting and resisting initiatives and measures aimed at achieving racial equality. On this background, the purpose of the present study was to empirically investigate expressions of white fragility, white counterreactions, and institu

European Reference Network eUROGEN Guidelines on the Management of Anorectal Malformations, Part II : Treatment

Introduction Anorectal malformations (ARMs) are rare birth defects affecting the anorectum and oftentimes the genitourinary region. The management of ARM patients is complex and requires highly specialized surgical and medical care. The European Reference Network eUROGEN for rare and complex urogenital conditions aimed to develop comprehensive guidelines for the management of ARM applicable on a E

Surprising results of patch testing with the baseline series in patients with photocontact allergy to ketoprofen

Objective: Photoallergic reactions due to topical ketoprofen are common. As some simultaneous contact allergies have been described in the literature, we aimed to get an overview of the pattern of reactivity towards common allergens in the baseline series in ketoprofen-photoallergic individuals. Methods: Using our database, we found 94 patients with photocontact allergy to ketoprofen diagnosed dur

Peroxynitrite scavenger FeTPPS binds with hCT to effectively inhibit its amyloid aggregation

Human calcitonin (hCT) is an endogenous polypeptide commonly employed in treating bone resorption-related illnesses, but its clinical application is limited due to its high aggregation tendency. Metalloporphyrins are effective in suppressing amyloid fibrillation, positioning them as potential drug candidates for amyloidogenic disorders like Alzheimer's and type 2 diabetes. In this work, we investi

The work–recovery cycle of kidney strain and inflammation in sugarcane workers following repeat heat exposure at work and at home

Purpose: To examine heat exposure at work and home and the work–recovery cycle and temporal variation of kidney strain, muscle injury and inflammation biomarkers in sugarcane workers. Methods: 20 male sugarcane workers (age: 33 ± 7 years) with a workplace Rest.Shade.Hydration (RSH) intervention were observed over 4 days, at the end (18 h post-shift recovery) and beginning of a work week (42 h post

Technical recommendations for implementation of Volumetric Modulated Arc Therapy and Helical Tomotherapy Total Body Irradiation

As a component of myeloablative conditioning before allogeneic hematopoietic stem cell transplantation (HSCT), Total Body Irradiation (TBI) is employed in radiotherapy centers all over the world. In recent and coming years, many centers are changing their technical setup from a conventional TBI technique to multi-isocenter conformal arc therapy techniques such as Volumetric Modulated Arc Therapy (

Pharmaceutical Industry Payments to Patient Organizations in Poland : Analysis of the Patterns, Evolution, and Structure of Connections

Drug company funding can create conflicts of interest that compromise the integrity of patient organizations, a problem studied primarily in Western Europe and North America. To address this research gap, we conducted a case study in Poland, a Central European country. Between 2012 and 2020, 33 companies reported payments worth €13 729 644 to 273 patient organizations in Poland. The funding was hi

The impact of government support on rural grocery stores—A regression discontinuity approach

We evaluate a place-based policy aimed at commercial service providers. In 2016, the Swedish government introduced special operating support for grocery stores in remote rural areas to slow down the process of store closures. We estimate the local causal effect in a regression discontinuity design framework using the fact that only stores located at least 15 km away from another store were eligibl

Imagining peace and enacting utopias in Puerto Rico

Local groups in Puerto Rico are often described as being at the forefront of climate transformation. This article explores active struggles towards alternate futures, using a critical concept of utopia in a phenomenological study alongside women at a community organisation in Culebra, Puerto Rico. I use feminist ethics of care as a theory of knowledge to study how cognitive, embodied, and affectiv

A Data-Driven Approach Identifies Subtypes of Caries From Dental Charting

Objectives: The objectives were to: (i) assess the accuracy of dental data for adults obtained from the Swedish Quality Register on Caries and Periodontitis (SKaPa); (ii) explore whether Latent Class Analysis (LCA) can identify groups of people based on caries data; and (iii) characterise the dental, medical and behavioural characteristics of people in the LCA-derived classes. Methods: Caries data

Effect of Oral Insulin on Early Combined Glucose and C-Peptide Endpoints in Individuals at High-Risk for Type 1 Diabetes

Background: The TrialNet Oral Insulin (OI) prevention trial showed no overall treatment effect, using the diagnosis of type 1 diabetes as an endpoint. A significant delay in onset was only found in a high-risk stratum (termed secondary stratum 1) of participants with low first-phase insulin release (FPIR).Methods: Since trials with an endpoint of type 1 diabetes take years to complete, in this pos

Microbial carbon utilization in a boreal lake under the combined pressures of brownification and eutrophication : insights from a field experiment

Climate and land use changes can increase terrestrial runoff to aquatic systems, leading to brownification and eutrophication in northern boreal lakes. Brownification may boost bacterial respiration and production, while eutrophication can enhance primary production and algal blooms. However, their combined effects on basal producers and bacterial carbon utilization are less understood. This study

Activity, structure, and diversity of Type II proline-rich antimicrobial peptides from insects

Apidaecin 1b (Api), the first characterized Type II Proline-rich antimicrobial peptide (PrAMP), is encoded in the honey bee genome. It inhibits bacterial growth by binding in the nascent peptide exit tunnel of the ribosome after the release of the completed protein and trapping the release factors. By genome mining, we have identified 71 PrAMPs encoded in insect genomes as pre-pro-polyproteins. Ha