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Fallbeskrivning : yngling överlevde direktträffar av kniv i hjärta och lunga

In Sweden, penetrating injuries to the lung and especially to the heart are fortunately rare. We hereby present a case-report on a young man who was stabbed in the right lung and heart. The paramedics arrived at the scene one minute after the alarm and instituted mechanical ventilation and fluid infusion. Ten minutes later the young man arrived at the emergency department. By then the patient was

Childhood exposure to polycyclic aromatic hydrocarbons (PAHs) and cardiometabolic indicators in childhood and adolescence : findings from a cohort study in rural Bangladesh

Background: Exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with cardiovascular diseases in adulthood, but studies examining childhood origins are scarce. Objective: To examine associations of childhood PAH exposure with cardiometabolic risk indicators in childhood and adolescence along with differences by sex. Methods: Urinary PAH metabolites [Σ1,2,3-hydroxyphenanthrene (Σ

Fetal exposure to a mixture of endocrine-disrupting chemicals and biomarkers of male fecundity : A population-based cohort study

Background: Fetal exposure to endocrine-disrupting chemicals (EDCs) has been associated with reduced male fecundity, but with few studies considering chemical mixtures. Objectives: We assessed the association between fetal exposure to a mixture of EDCs and biomarkers of male fecundity in young adulthood. Materials and methods: The study population comprised 841 young adult males enrolled in the Fe

pre-SUCCECS : Lessons learned from implementing resuscitation and stabilisation with an intact cord during caesarean sections – Focus group discussions with implementation teams

Objective: The primary aim of this study was to explore the lessons learned from implementing a procedure of resuscitation and stabilization with an intact umbilical cord for preterm and term infants requiring resuscitation or stabilization during emergency caesarean sections. Methods: Data were collected by two focus group discussions and one individual interview. Participants were members of imp

Moral distress among maternity and neonatal healthcare workers during the COVID-19 pandemic in Sweden : Results from the COPE staff longitudinal cohort study

Introduction: Moral distress arises when healthcare workers face difficult decisions without adequate information and/or when patient care is compromised due to limited resources, communication issues, or altered work routines in exceptional circumstances. While moral distress in maternity and neonatal healthcare workers (MNHCWs) has been noted, its prevalence, intensity, and impact on well-being

Reversal of Roux-en-Y Gastric Bypass to Normal Anatomy-Experience of 70 Patients

BACKGROUND: A limited subset of patients undergoing Roux-en-Y gastric bypass (RYGB) may develop intractable symptoms that ultimately require reversal to normal anatomy. Existing literature on this subject is characterized by small cohort sizes, substantial variation in surgical techniques, and limited follow-up durations. However, this study presents the largest single-center series to date, compr

A Reliabilism without Counterexamples and Reference Class Problems

In this article, I present a modified reliabilist theory of knowledge which purports to solve many of the problems currently facing standard reliabilism. With the help of a dispositionally construed reliabilist theory of knowledge and justification (DRK and DRJ), tentative responses to the following problems for reliabilism are offered: The New Evil Demon Problem, The Clairvoyance Problem, The Mr.

Ultrasound-assisted regeneration of ion exchange resins for efficient detoxification of lignocellulosic hydrolysate in biorefinery

Resin adsorption is an effective technology for the fermentable sugar slurry detoxification in lignocellulosic biorefinery, but with the great limitation of the loss of resin capacity from inhibitor contamination and the extensive use of acid and base solutions for their regeneration. In this study, we developed a green and practical method with ultrasound assisting the depletion of poisoned resin

Self-amplifying NRF2-EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) emerges from mutant KRAS-harboring but dormant low-grade pancreatic intraepithelial neoplasia (PanIN). To examine the role of oxidative stress, a putative PDAC risk factor, we established an organoid-based transformation system. Although the prototypic oxidant H2O2 induced organoid transformation, its effect was nonmutational and was mediated by the oxidant-

Circulating protein biomarkers and their association with vulnerable plaque characteristics – a PROSPECT II substudy

Background: In the PROSPECT-II study, near infrared spectroscopy (NIRS) and intravascular ultrasound (IVUS) was used to characterize atherosclerotic plaques in the coronary arteries. NIRS-derived lipid core burden index (LCBI) and IVUS-derived plaque burden (PB) were able to identify plaques strongly associated with adverse cardiovascular events. Aim: Our aim was to identify biomarkers associated

Statistical volume element generation for paperboard based on X-ray computer tomography images

The macroscopic response governed by a statistical volume element, generated from 3D X-ray computer tomography images of paperboard, is explored. The statistical volume element, which consists of fibres and void, is derived from X-ray computer tomography images. Two filters for computing intensity fields and intensity gradients have been implemented and compared. Using an intensity threshold, the

Anticipating airpocalypse : Air quality apps and implicit modes of anticipatory practices

Air quality apps are designed to observe air quality and inform publics about it, but also to elicit actions based on anticipated scenarios. As such, they may be seen as anticipatory technologies, cultivating environmental understandings and orienting users toward a specific future. This paper explores the anticipatory assemblages of these apps as well as users’ interactions with these apps and th

Brief Admission by Self-Referral : A 4-Year Follow-Up on Utilisation Patterns and Experiences

Brief Admission by self-referral (BA) is a crisis intervention for individuals with recurrent self-harm and suicidal ideation. While short-term effects are documented, long-term utilisation patterns remain unclear. This study examines BA usage over 4 years, identifies distinct utilisation profiles, and qualitatively explores participants' experiences with BA over time. Participants were 62 individ

Eco-friendly insect control in crop production

Insect pest control, which is essential for food and crop production, typically relies on chemical insecticides. At Yngvi Bio, we repurpose bacterial contractile injection systems as biodegradable insecticides, offering ecological safety, target specificity and a scalable path to market.

Perceptual, Semantic, and Pragmatic Factors Affect the Derivation of Contrastive Inferences

People derive contrastive inferences when interpreting adjectives (e.g., inferring that 'the short pencil' is being contrasted with a longer one). However, classic eye-tracking studies revealed contrastive inferences with scalar and material adjectives, but not with color adjectives. This was explained as a difference in listeners' informativity expectations, since color adjectives are often used

Anticipating the Damn Referent : How Comprehenders Rapidly Retrieve the Speaker's Attitude When Processing Negative Expressive Adjectives

Theoretical accounts of negative expressives such as damn have ascribed two main properties to this type of adjective, namely that they are typically speaker-oriented, and that they can be flexible with regard to their syntactic attachment. However, it is not clear what this means during online sentence processing. For example, is it effortful for comprehenders to derive the speaker's negative att

Slowdowns in scalar implicature processing : Isolating the intention-reading costs in the Bott & Noveck task

An underinformative sentence, such as Some cats are mammals, is trivially true with a semantic (some and perhaps all) reading of the quantifier and false with a pragmatic (some but not all) one, with the latter reliably resulting in longer response times than the former in a truth evaluation task (Bott & Noveck, 2004). Most analyses attribute these prolonged reaction times, or costs, to the st

Suppression of literal meaning in single and extended metaphors

Within Relevance Theory, it has been suggested that extended metaphors might be processed differently relative to single metaphoric uses. While single metaphors are hypothesized to be understood via the creation of an ad hoc concept, extended metaphors have been claimed to require a switch to a secondary processing mode, which gives greater prominence to the literal meaning. Initial experimental e

When irony is faster than its literal control : The role of mindreading during irony comprehension

Irony is a heavily context-dependent pragmatic phenomenon. But what is it about context that facilitates or blocks irony comprehension? Based on the echoic account, we suggest that a context facilitates irony comprehension when it makes manifest a speaker's intentions and attitude, i.e., when a context makes it easy for participants to engage their mindreading abilities. In two pre-registered self