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Modeling of DNA compaction by polycations

In this work we study polycations as efficient compacting agents of a medium size polyanion by means of Monte Carlo simulations. The systems are characterized in terms of a conformational analysis in which shape, overall dimensions, structure factors, radial distribution functions, and the degree of accumulation of the compaction agent near the polyanion are taken into consideration. Results show

MIMO PID Tuning via Iterated LMI Restriction

We formulate multi-input multi-output (MIMO) proportional-integral-derivative (PID) controller design as an optimization problem that involves nonconvex quadratic matrix inequalities. We propose a simple method that replaces the nonconvex matrix inequalities with a linear matrix inequality (LMI) restriction, and iterates to convergence. This method can be interpreted as a matrix extension of the c

Design Space Exploration for the integrated digital CNN Camera

The main thrust of CNN technology has been in analog implementations. Early attempts for digital implementations have a limited potential, confining the usage to for instance linear algorithms for B/W pictures. The paper looks into the prospects of successfully integrating the full CNN potential. This requires a carefully tuning of memory and network-on-chip bandwidth to the temporal/spatial aspec

Extended constituent-to-dependency conversion for English

We describe a new method to convert English constituent trees using the Penn Treebank annotation style into dependency trees. The new format was inspired by annotation practices used in other dependency treebanks with the intention to produce a better interface to further semantic processing than existing methods. In particular, we used a richer set of edge labels and introduced links to handle lo

Anxiety Disorders in Children and Adolescents with Autistic Spectrum Disorders: A Meta-Analysis

There is considerable evidence that children and adolescents with autistic spectrum disorders (ASD) are at increased risk of anxiety and anxiety disorders. However, it is less clear which of the specific DSM-IV anxiety disorders occur most in this population. The present study used meta-analytic techniques to help clarify this issue. A systematic review of the literature identified 31 studies invo

FPGA Controlled Pneumatic Variable Valve Actuation

A control system for pneumatic variable valve actuation has been designed, implemented and tested in a single cylinder test engine with valve actuators provided by Cargine Engineering AB. The design goal for the valve control system was to achieve valve lifts between 2 and 12 mm over an engine speed interval of 300 to 2500 rpm. The control system was developed using LabView and implemented on the

The Pd(100)-(root 5 x root 5)R27 degrees-O surface oxide revisited

Combining high-resolution core-level spectroscopy, scanning tunneling microscopy and density-functional theory calculations we reanalyze the Pd(100)-(root5 x root5)R27degrees-O surface oxide phase. We find that the prevalent structural model, a rumpled PdO(001) film suggested by previous low energy electron diffraction (LEED) work [Surf. Sci. 494 (2001) L799], is incompatible with all three employ

Size-dependent effects of an invasive herbivorous snail (Pomacea canaliculata) on macrophytes and periphyton in Asian wetlands

1. The invasive golden apple snail (Pomacea canaliculata), native to South America, is a serious pest on rice seedlings in south-east Asia and has also been shown to consume large amounts of macrophytes in natural wetlands, with large effects on ecosystem functioning. Earlier studies suggest that the snail undergoes an ontogenetic diet shift, feeding on algae and detritus as juveniles and shifting

The great disappearing act: difficulties in doing "leadership"

We address ideas and talk about leadership in a research and development (R&D) company. The meaning that middle and senior managers ascribe to leadership is explored. We show how initial claims about leadership values and style tend to break down when managers are asked to expand on how they perceive their leadership and account for what they actually do in this respect. We raise strong doubts

Profiles of occupational engagement in persons with schizophrenia, POES: Development of a new instrument based on time diaries

Previous time-use research suggests that it is highly relevant for an occupational therapist to estimate time use and occupational engagement in order to understand some of the determinants of wellbeing for people with schizophrenia. This article describes the development and the testing of the psychometric properties of an instrument, Profiles of Occupational Engagement in people with Schizophren

Floral costs in Nigella sativa (Ranunculaceae): Compensatory responses to perianth removal

Because internal resources are finite, it has been assumed that attractive, floral organs represent a significant drain on the energy and nutrient budget of a plant. Despite the broad significance of such trade-offs, in relatively few studies have investigators manipulated floral investments, then evaluated allocation to subsequently produced flowers, fruits, and seeds. In the present study of Nig

The eco-efficiency of tourism

The use of fossil energy is one of the major environmental problems associated with tourism and travel. Consequently, the need to limit fossil energy use has been highlighted as a precondition for achieving sustainable tourism development. However, tourism is also one of the most important sectors of the world economy, and fears have thus been expressed by the tourist industry and its organisation

Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes.

The purpose of this Phase II study was to evaluate if alum-formulated human recombinant GAD65 is safe and does not compromise beta cell function. The study was conducted as a randomized, double blind, placebo-controlled, dose-escalation clinical trial in a total of 47 Latent Autoimmune Diabetes in Adults (LADA) patients who received either placebo or 4, 20, 100, or 500 μg Diamyd subcutaneously at

The entrepreneurship factor in sustainable tourism development

Entrepreneurship is considered a central force of economic development, as it generates growth and serves as a vehicle for innovation and change., Tourism is one of the economic sectors in which a great degree of involvement is needed by the entrepreneurial sector: diversification of tourism products and services is needed to cope with increased demand for new types of tourism needs. These include

Visible-to-ultraviolet upconversion in Pr3+: Y2SiO5 crystals

The visible-to-ultraviolet upconversion in Pr3+:Y2SiO5 crystals have been investigated at room temperature for three different Pr3+ ion concentrations. The upconverted luminescence bands at the UV region from 270 to 350 nm were obtained with visible laser excitation. The upconversion mechanism was studied by observing the absorption and excitation spectra, the dependence of upconverted luminescenc