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Ruptured aneurysm at the perforating artery supplying the insula : Case report

OBJECTIVE: Aneurysms originating from perforating branches of the middle cerebral artery are quite rare. Most of them arise from the lenticulostriate arteries, frequently located within the basal ganglia. We report a perforating artery aneurysm that was entirely embedded within the limen insulae. CLINICAL PRESENTATION: A 41-year-old man presented with an insular hematoma without subarachnoid hemor

Lactoferrin-derived peptide PXL01 impacts nerve regeneration after sciatic nerve reconstruction in healthy and diabetic rats

INTRODUCTION: Although advanced surgical techniques are available, satisfactory functional outcomes after peripheral nerve injuries are uncommon. Hence, immune-modulating factors such as PXL01, a lactoferrin-derived peptide that improves axonal outgrowth in injured human digital nerves, have gained attention. We previously reported a short-term immunosuppressive effect of PXL01 after the repair of

Evaluation of hematological markers in minor head trauma in the emergency room

Introduction: A rule exists regarding the use of computed tomography (CT) for patients presenting to the emergency department with head trauma and a Glasgow coma score (GCS) of 15; however, it can be difficult to make this decision due to overcrowded emergency rooms or exaggerated patients complaints. We evaluated patients who presented to the emergency room with minor head trauma, and we aimed to

Sugar intake and cardiovascular disease risk: With an emphasis on genetic and metabolomic biomarkers of sugar intake

Introduction: Contrary to popular belief, there is limited research on sugar intake as a risk factor for cardiovascular disease. While the links between sugar-sweetened beverage intake and cardiovascular disease risk are well-established, little is known about the associations for overall added or free sugar intake and other dietary sources of added sugar. Objective markers of habitual sugar intak

Subdural empyema and unilateral pansinusitis due to a tooth infection

Paranasal sinus infections are very common. Dental infections, tumours and anatomical malformations can cause unilateral sinusitis. Most cases can be treated without complications. However, rare life-threatening intracranial complications can occur. Generally, an intracranial complication progresses rapidly and can cause meningismus, focal neurological disorders, loss of consciousness and seizures

Comparison of the toxicities of ethylene vinyl alcohol copolymer (EVOH) preparations, dimethyl sulphoxide and N-butyl 2-cyanoacrylate on cerebral parenchyma in an experimental rabbit model

AIM: Ethylene vinyl alcohol copolymer (EVOH), its organic solvent dimethyl sulfoxide (DMSO), and N-Butyl 2-Cyanoacrylate (NBCA) are widely used in neurovascular embolization procedures and yet with potential risk of cytotoxicity. The aim of this study was to evaluate the toxic effect of EVOH-DMSO, its solvent DMSO and NBCA on cerebral parenchyma in a rabbit model. MATERIAL and METHODS: Forty-eight

De novo formation of brain tumors in pediatric population following therapeutic cranial irradiation

Purpose: Tumors of central nervous system (CNS) are accounted as the second most common tumors in childhood (21 % of all cancers) following hematologic malignancies. The patients can suffer more than one cancer in their lifetime, and radiotherapy is claimed for de novo formation of a new tumor in years after treatment of an initial tumor. Methods: We have retrospectively analyzed our database for

Biomarkers associated with worsening renal function and progression in chronic kidney disease among patients hospitalized for acute heart failure

INTRODUCTION: Worsening renal function (WRF) is associated with poor prognosis in patients with heart failure (HF). Osteopontin (OPN) and Matrix extracellular phosphoglycoprotein (MEPE) are expressed in the kidneys and are involved in bone mineralization processes. Higher OPN levels have been associated with a higher risk for adverse outcomes in patients with chronic kidney disease (CKD), and MEPE

The Wolf Shall Dwell with the Lamb : permanent installation, Tel Aviv Jaffa

The sculpture, The Wolf Shall Dwell with the Lamb, is a contemporary adaptation of the prophecy of Isaiah (Chapter 11, Verse 6), installed as a suspended monument to world peace. At first glance, the figures of the wolf and lamb rest together, enveloped in cloth, as if frozen in a moment just before the public unveiling of the sculpture. Yet upon closer inspection, the fabric is revealed as insepa

From Nanoscale Design to Functional Integration of Magnetic Nanoparticle Assemblies : A Gas-Phase Strategy

The self-assembly of magnetic nanoparticles under external magnetic fields holds great potential for the facile fabrication of functional magnetic components with a wide range of applications. This work employs a technique based on electrically charged gas-phase magnetic nanoparticles, demonstrating an additional level of control when forming one-dimensional assemblies, so-called nanochains, as an

The Emergence and Development of the Danish Modal Particle Paradigm

This dissertation investigates the development of the main Danish modal particles jo, sgu, skam, nu, da, vel, nokand vist. In Modern Danish, these particles express contextualization instructions, that is, they express how theutterance relates to the interactive context. In addition to this common content core, they also share severalexpression features: they cannot be placed in the pre-field, the

Trust in Time : How the Impressionable Years, Detrimental Events and Collective Experiences Shape Social Trust

Denna avhandling är en sammanläggningsavhandling som består av tre enskilda forskningsartiklar som undersöker om och hur de inflytelserika åren, negativa händelser och kollektiva kriser påverkar social tillit – tron att dom flesta människor går att lita på. Trots det omfattande vetenskapliga intresset för social tillit, baseras större delen av tidigare forskning om hur social tillit formas över liThis dissertation is a compilation thesis comprised of three individual research articles that explore whether and how the impressionable years, detrimental events and collective crises predict social trust – the belief that most people can be trusted. Despite the widespread scholarly interest in social trust, most previous research in the formation of social trust over the life-course is based on

Exploring the Influence of Parental Mental Illness on Childhood Cancer Mortality: A Nationwide Cohort Study in Sweden

Background: Parents face mental health challenges following their child's cancer diagnosis. However, it is unknown whether parental mental illness following a childhood cancer diagnosis influences the child's mortality.Patients and methods: Using several nationwide registers in Sweden, we identified children diagnosed with cancer between ages 0 to 14 from 2005 to 2016. Parental mental illness was

AI Transparency in Trustworthy AI : From Metaphor to Governance Tool in EU Technology Regulation

Transparency has emerged as a fundamental component of ethical AI guidelines around the world. In the European Union (EU), it is recognised as one of the core principles for fostering Trustworthy AI, and serves as a cornerstone in building an ecosystem of trust within the AI governance framework.However, to support these ambitious policy objectives, the concept of transparency must be translated i

Management of cerebrospinal fluid leak during endoscopic pituitary surgery

Objective: Dural opening and closures are major steps in endoscopic pituitary surgery. Restoring the normal anatomy at the end of the procedure creates a natural barrier between the intrasellar compartment and the sinonasal cavity. Methods: In this study, we present a relatively simple dural opening and closure technique for endoscopic pituitary surgery. This technique provides a better alternativ