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Background: The mitral valve is essential for proper heart function. Patient-specific simulations may provide insights into valve function and provide hemodynamic information for treatment planning. This study presents a framework for patient-specific mitral valve hemodynamic prediction and the validation of the simulation model against echocardiographic and MRI data. Methods: Ten healthy voluntee
Nitrogen removal from wastewater with anammox saves energy and resources. Partial denitrification-anammox (PDA) is a promising process alternative for municipal wastewater treatment, given that the understanding about how to control the microbiome and its activity reach sufficient level. Here, two moving bed biofilm reactors were fed with either acetate or propionate to study the role of organic c
This article develops an argument that in hybrid regimes, different levels of party competition incentivize incumbents to subvert the police in distinct ways, resulting in more corrupt or more repressive policing practices. In competing-pyramid hybrid regimes, such as Ukraine (2013–2019), elites have stronger incentives to preserve police corruption as a tool for immediate resource extraction amid
The formation of platoons, where groups of vehicles follow each other at close distances, has the potential to increase road capacity. In this paper, a decentralized control approach is presented that extends the well-known constant headway vehicle following approach to the two-dimensional case, i.e., lateral control is included in addition to the longitudinal control. The presented control scheme
Segmental gain of chromosome 17q is the most common genetic aberration in high-risk neuroblastoma, but its role in disease progression is poorly understood. This study aims to address the contribution of 17q gain to neuroblastoma malignancy. We analyzed the genetic and transcriptional landscape of 417 neuroblastoma patients across various risk groups and clinical stages using multi-omic approaches
OBJECTIVES: To investigate hip dysplasia as a risk factor for clinically relevant and incident radiographic hip OA.METHODS: From a prospective cohort (CHECK) of 1002 middle-aged, new consulters for hip and/or knee pain, 468 hips (251 individuals) were selected based on hip pain, available lateral center edge angle (LCEA) and absence of definite radiographic hip OA (Kellgren and Lawrence [KL] grade
The relationship between degree of coronary artery stenosis and its effect on myocardial perfusion is complex and constitutes a clinical challenge. The aim of this study was to assess diagnostic accuracy of visual assessment of invasive coronary angiography (ICA) for detecting reduced myocardial perfusion determined by quantitative first-pass perfusion (qFPP) cardiac magnetic resonance (CMR) in pa
In this work we investigate the development of functionally graded cemented carbides, featuring macro gradients on the millimeter scale, where Fe, or Ni is the binder phase. Two composites, WC-Ni and WC-Fe with 20 % binder by volume were produced by addition of TiC on the surface of the samples before sintering at 1475 °C for 1 h. The sintered samples were analyzed using electron microscopy and mi
Many women are occupationally active during pregnancy. The aim of this study was to investigate associations between exposure to chemicals during pregnancy and the risk of gestational diabetes or preeclampsia. The cohort included singleton births in Sweden between 1994 and 2014. The cohort was limited to low-educated mothers to reduce potential confounding from unidentified life-style associated f
Despite the importance of mineral-associated organic matter (MAOM) in long-term soil carbon (C) and nitrogen (N) persistence, and the significant contribution of fungal necromass to this pool, the factors controlling the formation of fungal-derived MAOM remain unclear. This study investigated how fungal necromass chemistry, specifically melanin, interacts with soil mineral properties and microbial
Chronic breathlessness is a common and distressing symptom, negatively impacting physical function and quality of life. Many individuals presenting with chronic breathlessness wait years for an explanatory diagnosis, leading to delays in accessing effective treatments and worse individual outcomes including premature mortality. In addition, delays to diagnosis are associated with increased healthc
The incidence of parameningeal infection (PI) is increasing in the context of therapy-induced immunosuppression. PI often presents with atypical symptoms, leading to delayed diagnosis and intervention, and can result in severe neurological sequelae. However, current understanding of PI remains limited due to a lack of basic research on host-pathogen interactions. Here, we first established a trans
I artikeln analyseras förfarandereglerna i den svenska tilläggsskattelagstiftningen och deras förenlighet med unionsrätten och Europakonventionen. Fokus ligger på aspekter kopplade till rapportering, sanktionsavgifter och potentiellt oskäliga skatteuttag. Särskild uppmärksamhet ägnas åt frågan om den förenklade tilläggsskatterapportens rättsliga status, risken för dubbelbestraffning i strid med ne
After a decade of data falsification scandals and replication failures in psychology and related empirical disciplines, there are urgent calls for open science and structural reform in the publishing industry. In the meantime, however, researchers need to learn how to recognize tell-tale signs of methodological and conceptual shortcomings that make a published claim suspect. I review four key prob
Lidar technology was utilized to non-destructively explore the diverse insect life in the Taï virgin forest of Côte d'Ivoire. This study employed an entomological Lidar scanned at different elevation angles, combined with traditional insect trapping at different canopy heights, to investigate the composition and spatial-temporal distribution of insects within the forest canopy. We detected stratif
This article presents a comprehensive database featuring the digitized, cleaned, geocoded, and linked data of the Swedish manufacturing censuses between 1863 and 1900. The data covers close to the universe of Swedish manufacturing activity and includes establishment-level information on workers, the sum of production value, and toll as output value. The article describes how the data was originall
The use of bio-based materials offers opportunities to mitigate the climate impacts of construction, with buildings potentially acting as carbon sinks. However, it remains unclear what a future bio-based construction sector will look like. One reason for this are diverse socio-technical visions for the use of bio-based construction materials. In this paper, we use discourse analysis across a compr
Combustion properties and combustion chemistry of ammonia (NH₃) are significantly different from those of hydrocarbons and thus require further investigation. NH₃ combustion with oxidizers different from the ambient air can reveal distinct chemistry of NOx formation, which, together with low reactivity, is one of the major obstacles in the direct deployment of ammonia as a practical fuel. In the p
