In this thesis we performed a pooled cohort study to investigate the role of radiomics in head and neck cancer prognosis. The aim was to investigate prognostic value for overall survival and cancer recurrence of radiomics combined with previously studied demographic and clinical risk factors. Radiomics features were extracted from the gross tumor volume on a computed tomography captured prior to r

In the past decade, studies have examined how the Russian-speaking minority reacted to changes in citizenship, language, and memory politics. However, one aspect that has not been studied is the response to educational policy changes during an ongoing conflict. This study investigates the resistance strategies of Russian-speaking mesolevel actors against minority education policy changes before an

Nanowires are promising structures for improving light absorption due to their enhanced optical properties compared to bulk materials. Silicon is a suitable semiconducting material for driving water splitting in a photoelectrochemical (PEC) cell, and is particularly attractive due to its small bandgap as well as its relative abundance and low cost. PEC cells can be enhanced by including silicon na

Photoperiod, the relative duration of daylight in a 24-hour diel-cycle, is an environmental cue that influences physiological processes in birds, regulating life-history events such as reproduction and migration. Here we study whether variations in photoperiod affect migratory behaviors, including activity, orientation, and body mass, across bird species during 2023 spring and autumn migration. Ou

Understanding the dynamic of a population via either abundance or density is crucial for wildlife conservation. The brown bear (Ursus arctos) is a commonly distributed, yet elusive species, playing a major role in the ecosystem. Usually monitored with genetic sampling, hunted bags, or telemetry data, the use of camera traps for bear monitoring is still to this day a rarely used, yet promising meth

Restaurering av betesmarker i Ecuador: Växtkrav för Salvia corrugata och Macleania rupestris Övergivna betesmarker och fält i det syd-andinska landskapet i Ecuador har ofta under lång tid utsätts för urlakning av näringsämnen och jordpackning, något som begränsar den naturliga etableringen av träd och buskar. Då mängden övergiven mark ökar blir landskapet alltmer fragmenterat och inhemska växt arThe Andes of Ecuador are known for an outstanding biodiversity but is also a region where the abandonment rate of agricultural land is high, highlighting the need for forest restoration with native species. Here, the germination and growth requirements for propagation of the hummingbird pollinated bush species Salvia corrugata and Macleania rupestris were studied to better understand their suitabi

Heathlands have been identified as ecosystems which store large amounts of carbon, especially in soil, which is very important for climate change mitigation. Ericoid mycorrhizae, which are the symbiosis between mycorrhizal fungi and ericaceous plants and which often dominate in heathlands, have been proposed as drivers of soil organic carbon storage through their production of recalcitrant melaniz

Lunds Universitetssjukhus är det största sjukhuset i Skåne. Sjukhuset närmar sig 100 år och behöver moderniseras och därför kommer en omplacering av sjukhusområdet att göras omkring år 2040. Denna studie undersöker svagheter och möjligheter för kollektivtrafik till det nya sjukhusområdet för att kunna möta behovet av kollektivtrafik år 2040. Studien bygger på en litteraturstudie tillsammans med enThis study examines the challenges and opportunities for public transport to meet the future demand for Lund University Hospital which will be reloacted in 2040. Based on a survey targeting on employees at the current hospital (N=780), the result reveals that employees younger than 40 are driving as much as the group above 65, while the age group between 40 and 65 is mostly using either public tra

Anolis sagrei exhibit a female limited dorsal pattern polymorphism with two discrete pattern morphs (chevron or diamond). The underlying genetic basis has been traced to a Mendelian autosomal locus (gene CCDC170) which is adjacent to the gene for estrogen receptor one (ESR1). Thus, this model system gives an excellent opportunity to study the origin and maintenance of new phenotypic variants. In t

Naturlig selektion i vilda skalbaggspopulationer Naturlig selektion är en nyckelfaktor för evolutionen. Även om vi vet att mängden variation i egenskaper (fenotyper) ger råmaterial för selektion och om den är genetisk påverkar evolutionens hastighet, har vi fortfarande mycket att lära om hur naturlig selektion påverkar specifika egenskaper över tid. I min examensuppsats undersökte jag hur naturliNatural selection is an important force behind evolution. It is well known that phenotypic variation provides opportunity for evolution, but research into how selection acts on specific traits over time is lacking. In this thesis, I studied how selection acts upon the shape and body size of the beetle Cassida viridis. Across three populations, I measured size (length and area), shape, and lifespan

Billions of birds migrate thousands of kilometres twice a year. The migration is an energetic challenge, with over 70% of the total energy expenditure being spent at stopover sites. There are different strategies birds can use to conserve energy, such as reducing the metabolic rate. This study aimed to investigate the potential nighttime energy saving in long-distance versus short-distance migrati

Involving a controlled reduction of body temperature (lowering of 3 - 10 °C), nocturnal hypothermia is a common strategy among birds to manage the high energy expenditure required for body temperature regulation, particularly during periods of elevated metabolic demands. In this study, I investigated whether migrating passerines generally use controlled nocturnal hypothermia as a migratory strateg

Biofilms are intricate bacterial communities prevalent in diverse environments and rely on complex physiological adaptations and interactions to manifest community-intrinsic properties. The biofilm matrix itself is a major contributor to biofilm dynamics, as one of the mediators of the interactions within the biofilm, and it is composed of a diverse array of molecules. This project focuses on Sten

Recent years have seen an increase in reports on rising wildfire occurrences in countries of the Middle East. Wildfires are integral parts of terrestrial ecosystems and as such prone to the recent, large-scale anthropogenic changes of global ecosystem dynamics. However, the systematic analysis of patterns of wildfire occurrences – fire regimes – is concentrated on a few well studied regions and re

The following thesis seeks to explore the role of myth-making and securitisation in the United Kingdom’s ontological security and identity formation, as seen in their discourses surrounding security and the normalisation of far-right imaginaries and sentiments. It uses the United Kingdom as a case study in lieu of studying the larger phenomena of how national identity has been framed in security d

Behovet av förnybar energi är stort och förväntas öka i framtiden. I Sverige står vattenkraft för en betydande andel av elproduktionen, där anläggningarna ofta innebär fysiska hinder för vandringsberoende fiskarter. För att bibehålla elproduktionen och samtidigt säkerställa god konnektivitet i vattendragen krävs väl fungerande migrationslösningar förbi kraftverken, både för uppströmsvandrande och The need for renewable energy is substantial and is expected to increase in the future. In Sweden, hydropower accounts for a significant portion of the energy production, with facilities often presenting physical barriers to migratory fish species. To maintain electricity production while ensuring good connectivity in watercourses, effective migration solutions past the power plants are required f

Mechanisms of chemotherapy resistance in childhood cancer Cancer is a group of diseases in which cells start to divide uncontrollably, until they start to invade other tissues. Neuroblastoma is the third most common early childhood cancer. It develops in the sympathetic nervous system, and it is most often found in the adrenal gland. High-risk neuroblastoma is challenging to treat and has poor pr

Att framställa färger via olinjär optik Genom att studera ljus, i synnerhet dess interaktioner med materia, har mängder av framsteg gjorts inom teknik och vår förståelse för universums lagar. Lasern var en revolutionerande teknik när den kom 1960, och den möjliggör idag forskning inom extremt korta tidsskalor med hög intensitet. Ultrakorta laserpulser, som endast är några femtosekunder (10^−15 s)In recent years, the Multi-Pass Cell (MPC) has been increasingly employed and researched upon, after emerging as a promising post-compression technique for making ultrafast laser pulses shorter. Like most post-compression techniques, MPCs utilize a nonlinear effect, Self-Phase Modulation (SPM), which stems from the intensity-dependence of the refractive index of certain nonlinear materials, to ove

MORC2 (Microorchidia CW type Zinc Finger protein 2) is a GHKL (gyrase, heat shock protein 90, histidine kinase, MutL) ATPase involved in chromatin remodeling and is highly conserved in eukaryotes. Mutations in the ATPase domain of MORC2 are known to cause neurodevelopmental disorders. MORC2 is recruited by the HUSH complex to target long, intronless transcription units such as LINE-1 retrotranspos

Cancer immunotherapy employs the patients' own immune system to eradicate the tumor. The success of immunotherapies largely depends on an immune cell population, called T cells. T cells have the capacity to differentiate between healthy and malignant cells based on mutations that are displayed on the surface of cancer cells. After recognition of the tumor cell, T cells induce killing. However,