Chromosomal instability is a common feature in malignant tumors. Previous studies have indicated that inactivation of the classical tumor suppressor genes RB1, CDKN2A and TP53 may contribute to chromosomal aberrations in cancer by disrupting different aspects of the cell cycle and DNA damage checkpoint machinery. We performed a side-by-side comparison of how inactivation of each of these genes aff

In this paper we look at the adaption of SI-PASS programmes during the COVID-19 pandemic drawing from four Higher Education Institutions (HEIs) as case studies: The National University of Ireland (NUI) Galway in Ireland, Nord University in Norway, Lund University in Sweden and the University of Manchester in the UK. The paper also focuses on the role of SI-PASS in student engagement in an extraord

Altered sensory processing has been linked to symptoms of obsessive-compulsive disorder (OCD) and anxiety disorders (ADs) in youth, but few studies have examined sensory processing in clinical samples and no study has analyzed self-report data from youth meeting diagnostic criteria for OCD or ADs. This study included 86 youth with OCD, 82 youth with ADs, and 46 youth without psychiatric disorders.

At the Museum of World Culture (former Etnografiska Museet i Göteborg) there is an archaeological collection from the Santa Maria and Calchaqui Valleys of north-western Argentina, which came to the museum in 1930. In this article we will focus on six well-preserved objects with provenience from Quilmes and La Quebrada del Carmen in the Santa Maria Valley. In addition to the good conservation of th

I forskningsprojektet Välfärdsstaten analyserad (1945–89) arbetar vi med olika typer av algoritmisk textanalys av storskalig empiri från politikens sfär (digitaliserat riksdagstryck och statliga offentliga utredningar under perioden), dagspress och skönlitteratur. Svensk efterkrigstid är en väl utforskad period, men genom att applicera digitala metoder på kurerade dataset kan politikens, nyhetsmedA hundred million words: Reflections on historical research with large-scale textual datasets as empirical evidenceThe research project Welfare State Analytics: Text Mining and Modelling Swedish Politics, Media & Culture, 1945–1989 uses probabilistic methods and text-mining models to study three massive textual datasets from Swedish politics, news media, and literary culture. By topic modellin

How is the ongoing “datafication” in society experienced by consumers? Critical discussions regarding the impact of datafication on consumers seldom study consumers’ actual experiences. Conversely, the studies that do exist of consumers and their experiences of datafication tend to take an individualistic approach, arguing that how consumers experience and respond to the ongoing datafication is th

Due to limitations of IoT networks including limited bandwidth, memory, battery, etc., secure multicast group communication has gained more attention, and to enable that a group key establishment scheme is required to share the secret key among the group members. The current group key establishment protocols were mostly designed for Wireless Sensor Network, and they require device interaction, hig

Internet of Things (IoT) firmware upgrade has turned out to be a challenging task with respect to security. While Over-The-Air (OTA) software upgrade possibility is an essential feature to achieve security, it is also most sensitive to attacks and lots of different firmware upgrade attacks have been presented in the literature. Several security solutions exist to tackle these problems. We observe

Sommaren 1888 organiserade en grupp unga kvinnor en strejk som skakade om den brittiska arbetsmarknaden. De så kallade tändsticksflickorna på fabriken Bryant and May i östra London kämpade inte bara för bättre löner och rimliga villkor. Ytterst stod deras liv och hälsa på spel.

BackgroundCentrally inserted totally implanted vascular access ports (PORTs) and peripherally inserted central catheters (PICCs) are widely used for the administration of chemotherapy. Our aim was to study the incidence of catheter-related deep venous thrombosis in patients with cancer receiving chemotherapy through either a PICC or a PORT.MethodsAdults with non-haematological cancer (mainly breas

Vascular dysfunction and organ failure are two distinct, albeit highly interconnected, clinical outcomes linked to morbidity and mortality in human sepsis. The mechanisms driving vascular and parenchymal damage are dynamic and display significant molecular cross talk between organs and tissues. Therefore, assessing their individual contribution to disease progression is technically challenging. He

OBJECTIVES: We aimed to investigate whether sleep duration is associated with self-reported overall health, screen time, and nighttime texting among Swedish adolescents.METHODS: This was a cross-sectional survey of students (n = 1518) aged 13 to 15 years (50.7% girls) in southern Sweden.RESULTS: Fewer than 8 hours sleep duration before a school day was reported by 31% of students. The median time

Nanoplastics are defined as plastic particles broken down to extremely small sizes (1–100 nm) with unknown effects to the human body and immune system. Air and food exposure scenarios involving blood, lungs and intestine are considered in the literature. The fact that plastics also needs to pass the nose, oral cavity, and throat is so far ignored in the literature. The tonsils are immunologically