Search results

Filter

Filetype

Your search for "*" yielded 530840 hits

Effectiveness of elevated intraocular pressure as a criterion for glaucoma referral after 6 years of follow-up

Purpose: To evaluate the long-term predictive value of the need to treat patients referred by optometric practitioners, regarding glaucoma, in Malmö, Sweden, using intraocular pressure (IOP) as the primary referral criterion. Patients and Methods: This retrospective study included 94 of 108 (87%) individuals referred to the Skåne University Hospital in Malmö, Sweden, for elevated IOP during 2012–

Traces of a Swedish army camp from 1644 revealed at Uppåkra by extensive magnetometer survey

In the framework of an archaeological prospection case study conducted at the Swedish Iron Age site of Uppåkra near Lund, a large number of anomalies caused by buried archaeological remains were detected using extensive magnetic surveys. Written sources report that the Swedish army under Field marshal Gustav Horn had established a camp near the village of Uppåkra in autumn 1644, awaiting the appro

Serum proteome modulations upon treatment provides biological insight on response to treatment in relapsed mantle cell lymphoma

Background: The possibility to monitor patient's serum proteome during treatment can provide deepened understanding of the biology associated with response to specific drugs. Non-invasive serum sampling provides an opportunity for sustainable repetitive sampling of patients, which allows for more frequent evaluation of the biological response and enhanced flexibility in treatment selection in cont

Trailblazing precision medicine in Europe : A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany

Over the last decades, rapid technological and scientific advances have led to a merge of molecular sciences and clinical medicine, resulting in a better understanding of disease mechanisms and the development of novel therapies that exploit specific molecular lesions or profiles driving disease. Precision oncology is here used as an example, illustrating the potential of precision/personalized me

Real-Time Event-Driven Classification Technique for Early Detection and Prevention of Myocardial Infarction on Wearable Systems

A considerable portion of government health-care spending is allocated to the continuous monitoring of patients suffering from cardiovascular diseases, particularly myocardial infarction (MI). Wearable devices present a cost-effective means of monitoring patients' vital signs in ambulatory settings. A major challenge is to design such ultra-low energy devices for long-Term patient monitoring. In t

Burr hole craniostomy versus minicraniotomy in chronic subdural hematoma: a comparative cohort study

BACKGROUND: Chronic subdural hematoma (CSDH) is one of the most common neurosurgical diseases. In surgical management of CSDH, there is a lack of standardized guidelines concerning surgical techniques and a lack of consensus on which technique(s) are optimal. Neurosurgical centers have shown a wide variation in surgical techniques. The purpose of this study was to compare two different surgical te

Industrious migrants: gender and the earnings of migrants in Swedish manufacturing around 1900

Migration played a central role in industrialisation by reallocating labour from the countryside to urban areas and centres of manufacturing where it was in high demand, and better remunerated, with implications for economic growth and individual well-being. We investigate the labour market performance of internal migrants in Sweden around the turn of the last century; a period of industrialisatio

Mitochondrial dysfunction and the metabolism - studies on respiratory chain disorders

Background: Mutations of the mitochondrial assembly factor BCS1L disrupt assembly and function of the respiratory chain complex III (CIII) and thereby result in energy deprivation. In GRACILE syndrome, the BCS1L mutation causes a liver disorder that leads to metabolic disturbances associated with severe growth restriction.Objectives: To clarify the mechanisms and affected metabolic pathways in the

Challenges of Adopting SAFe in the Banking Industry – A Study Two Years After Its Introduction

The Scaled Agile Framework (SAFe) is a framework for scaling agile methods in large organizations. We have found several experience reports and white papers describing SAFe adoptions in different banks, which indicates that SAFe is being used in the banking industry. However, there is a lack of academic publications on the topic, the banking industry is missing in the scientific reports analyzing

Thrombospondin-2 as a diagnostic biomarker for distal cholangiocarcinoma and pancreatic ductal adenocarcinoma

Purpose: Distal cholangiocarcinoma and pancreatic ductal adenocarcinoma are malignancies with poor prognoses that can be difficult to distinguish preoperatively. Thrombospondin-2 has been proposed as a novel diagnostic biomarker for early pancreatic ductal adenocarcinoma. The aim of the present study was to evaluate thrombospondin-2 as a diagnostic and prognostic biomarker in combination with curr

Age- and sex-specific prevalence of serious bacterial infections in febrile infants ≤60 days, in Sweden

Aim: The aim of the study was to describe age- and sex-specific prevalence of serious bacterial infections (SBI: urinary tract infection, bacteraemia, meningitis) among febrile infants ≤60 days in Sweden. Methods: This is a retrospective study in 4 Pediatric Emergency Departments from 2014 to 2017, in previously healthy, full-term infants ≤60 days with fever without a source. Results: Of the 1,701