Transfer RNA modifications and modifying enzymes in Saccharomyces cerevisiae
Transfer RNAs are adaptor molecules, which decode mRNA into protein and,thereby, play a central role in gene expression. During the maturation of a primarytRNA transcript, specific subsets of the four normal nucleosides adenosine,cytidine, guanosine, and uridine are modified. The formation of a modified nucleosidecan require more than one gene product and may involve several enzymaticsteps. In the