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In this chapter, I describe how technological progress triggers and shapes structural change within the economy and society, which in turn—if the resulting changes are significant enough—may shift the scope and outcome of established legislation and regulatory frameworks. The argument presented focuses on the ongoing digitalization, using its common technological characteristics to identify and de

The second Weiglhofer Symposium on Electromagnetic Theory concluded with a round table discussion on “Future Developments.” The panel featured Ibrahim Abdulhalim from the ECE School at Ben Gurion University, Gérard Gouesbet from the Institut National des Sciences Appliquées de Rouen, Gerhard Kristensson from Lund University, Guy Vandenbosch from Katholieke Universiteit Leuven, and Theo Rasing from

Colon capsule endoscopy is a noninvasive imaging technology primarily designed to provide detailed visualization of the colon. While the main intention of this technology is to examine the large intestine, it also captures images from the oral cavity through the small intestine as the capsule travels along the gastrointestinal tract. This chapter outlines the anatomical regions and landmarks obser

Digitalization, including recent and rapid advances in the field of artificial intelligence (AI), constitutes a technological shift on a scale comparable to the introduction of the steam engine or electricity. This shift has altered the way we organize work and business, how we interact socially and shop. But what are the implications for other parts of the economy? What are the consequences for t

The tax system is essential for financing our public welfare and the public sector. The tax system and its capacity to generate tax revenue typically reflect the structure of the economy and as the economy changes the tax system needs to adapt. This anthology brings together different perspectives on how digitalization changes or may change the conditions for how the tax ecosystem functions, from

Foodomics tools are ameliorating the compositional and quality analysis part of various domains of food products. The use of proteomics in the polymorphic product investigation of beta-casein (β-Cn) is intriguing because of the fast and reliable results from the accurate mass spectrometry. This study delineates the LC-MS/MS-based sequential analysis of gel fractionated β-Cn of eighteen Holstein Fr

The current novel study aims was to development and characterization of gum based (guar gum: almond gum) composite formulations with or without addition of oregano essential oils to extend the shelf life of okra at ambient condition. In this study, the optimized composite of guar gum: almond gum (75:25 V/V) prepared with addition of different concentrations (0.05, 0.1 and 0.15 % (V/V) of oregano e

Microbial bio-aroma synthesized from biowaste, and its marketing is an emerging aspect of future research due to their benefits. However, the sensory lexicon of bio-aroma has not yet been developed so far. This study aims to identify the smell characteristics of bio-aroma produced by fermentative yeast Kluyveromyces marxianus by solid-state fermentation, where the sample was extracted from ferment

Foodomics is an emerging probing method of phenotype investigation of the different milk proteins and their subtypes. The polymorphic nature of the β-casein (β-Cn) protein has shown fourteen different protein variants to date in bovines. The analysis of the β-Cn genetic polymorphism from the milk of the crossbred dairy animals is crucial for the quality assurance of the consumers from the various

Data acquisition and integration are vital aspects of circular industrial initiatives and help industries develop balanced coordination with other stakeholders and commitment to circular standards. Small and medium-sized enterprises hesitate to implement the necessary automation and information collection process because of high investment issues. The dairy industry does have a growing need for pr

This paper studies the time-dependent first-in-first-out (FIFO) queuing model with a single intermittently available server and variable-sized bulk arrivals and bulk departures. The time between arrivals, servicing time, and server availability time follows an exponential distribution. The difference-differential equations are used for developing system equations, and the Laplace transforms (L.T.)

This chapter reviews the growing body of epidemiological evidence linking long-term exposure to ambient air pollution with increased risk of dementia, including Alzheimer’s disease (AD) and vascular dementia (VaD). With air pollution now recognized as a potentially modifiable risk factor, the chapter explores mechanistic pathways, such as neuroinflammation and oxidative stress, through which pollu

The increasing complexities and vulnerabilities in globalised supply chains, exacerbated by recent crises such as pandemics, climate change, and geopolitical disruptions, have underscored the urgent need for sustainable and resilient supply chain management. The growing interdependence of global trade networks makes them more susceptible to disruptions, highlighting the importance of digital trans

The European Union (EU) has recently presented several new legal proposals for promoting ecodesign and product labeling. The aim is to harmonize national practices and rules in the EU, to regulate issues like product lifetime and repairability in a more comprehensive way, to introduce new tools like digital product passports, and to introduce labeling schemes for repairability and durability. In p

Immunotherapy options for immune cold tumors, like prostate cancer, are limited. We show that AR downregulates MHCI expression/antigen presentation and that AR inhibition improves T-cell responses and tumor control. This suggests that treatments combining AR inhibitors and checkpoint blockade may improve tumor immune surveillance and antitumor immunity in patients.

The androgen receptor (AR) is central in prostate tissue identity and differentiation, and controls normal growth-suppressive, prostate-specific gene expression. It also drives prostate tumorigenesis when hijacked for oncogenic transcription. The execution of growth-suppressive AR transcriptional programs in prostate cancer (PCa) and the potential for reactivation remain unclear. Here, we use a ge

In preclinical studies, p53 loss of function impacts chemotherapy response, but this has not been consistently validated clinically. We trained a TP53-loss phenocopy gene expression signature from pan-cancer clinical samples in the TCGA. In vitro, the TP53-loss phenocopy signature predicted chemotherapy response across cancer types. In a clinical dataset of 3003 breast cancer samples treated with

Despite the average 5-year survival rate exceeding 85%, childhood cancer is still the most common cause of disease-related death among children in Sweden. A cancer diagnosis is profoundly traumatic not only for children themselves, but also for the entire family, particularly the primary caregivers, their parents. This project aimed to investigate the extent to which a childhood cancer diagnosis a