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Surgical management of cytologically indeterminate thyroid nodules

Nodules in the thyroid are frequent. Preoperative investigations including fine-needle cytology and ultrasound cannot in all patients rule out malignancy. Thus, surgical excision for histopathologic examination is often needed. In this narrative review, we examine aspects of the surgical management of indeterminate thyroid nodules, using a comprehensive review of the available literature. The auth

Understanding acceleration : An interplay between different mathematics and physics representations

Acceleration is often viewed as abstract - but when a person accelerates, e.g. in a car or on swings, trampolines, carousels or rollercoasters, the force required for the acceleration is felt throughout the body. If acceleration is introduced as force divided by mass rather than as a second derivative of displacement, the concept can be made accessible to much younger learners, such as 10-year old

Training teachers to use playgrounds in physics teaching

Climbing racks, carousels, swings and slides can be used for many experiments and demonstrations that offer suprising results, often challenging students' understanding of motion. This paper describes activities used in professional development workshops for teachers on the use of playgrounds in physics teaching. Toys and other simple equipment complement the experience of the body. In addition, s

Antibody-Fragments: Protein Engineering, Process Development, and their Application as Affinity Ligands

Monoclonal antibody (mAb) fragments have become the formats of choice for both biopharmaceuticals and ligands in analytical and preparative applications. Their smaller size enables additional advantages over full-length mAbs, such as improved tissue penetration, faster blood clearance for diagnostic applications, improved capacity, and enablement of multivalent formatting. However, limitations in Monoclonal antibody (mAb) fragments have become the formats of choice for both biopharmaceuticals and ligands in analytical and preparative applications. Their smaller size enables additional advantages over full-length mAbs, such as improved tissue penetration, faster blood clearance for diagnostic applications, improved capacity, and enablement of multivalent formatting. However, limitations in

High spin states of the normally deformed bands of y 83

Level lifetime and side-feeding time measurements were performed on the excited states of the normally deformed bands of Y83 using the Doppler-shift attenuation method (DSAM). The high spin states of Y83 were populated using the fusion-evaporation reaction Ni58(S32,α3p)Y83 at 135 MeV. Twenty-two level lifetime and side-feeding times were determined in most of the cases by comparing the line shapes

Radio channel measurement and modelling techniques

This chapter is dedicated to radio channel measurement and modelling techniques for beyond 4G networks, in particular: • new measurement techniques not only targeting radio channels, but also material properties in new frequency bands (Section 9.1), • improved physical models, cowering full-wave as well as ray-based methods, with a specific sub-section dealing with diffuse scattering (DS) and comp

Organisational models of Health services for Children and adolescents in out-of-home care: Health technology assessment

AimDecades of research confirm that children and adolescents in out‐of‐home care (foster family, residential care) have much greater health care needs than their peers. A systematic literature review was conducted to evaluate organisational health care models for this vulnerable group.MethodsA systematic literature search was undertaken of the following databases: Academic Search Elite, CENTRAL, C

To shake or not to shake : 13 C-based evidence on anaerobic methane oxidation in paddy soil

The anaerobic oxidation of methane (AOM) removes most of the biologically produced methane (CH 4 ) from marine ecosystems before it enters the atmosphere and thus mitigates greenhouse gas emissions. As compared to marine environments, surprisingly little is known about the role of AOM in terrestrial ecosystems. Particularly, how AOM controls the CH 4 budget of paddy soils is unexplored, partly

Maize phenology alters the distribution of enzyme activities in soil : Field estimates

Microbial processes mediated by soil enzymes are crucial in soil organic matter decomposition, resulting in release of nutrients that become available for plant and microbial uptake. Therefore, it is crucial to know the sensitivity of enzyme activities (EA) along soil depths at distinct plant vegetation stages, and how the availability of mineral nitrogen (N) alters EA. We studied effects of N fer

Decadal Nitrogen Fertilization Decreases Mineral-Associated and Subsoil Carbon : A 32-Year Study

Crop residues and manure are important sources of carbon (C) for soil organic matter (SOM) formation. Crop residue return increases by nitrogen (N) fertilization because of higher plant productivity, but this often results only in minor increases of SOM. In our study, we show how N fertilization and organic C additions affected SOM and its fractions within a 32-year-long field-experiment at Puch,

Microbial decomposition of soil organic matter is mediated by quality and quantity of crop residues : mechanisms and thresholds

Crop residue quality and quantity have contrasting effects on soil organic matter (SOM) decomposition, but the mechanisms explaining such priming effect (PE) are still elusive. To reveal the role of residue quality and quantity in SOM priming, we applied two rates (5.4–10.8 g kg−1) of 13C-labeled wheat residues (separately: leaves, stems, roots) to soil and incubated for 120 days. To distinguish P

Decrease of soil organic matter stabilization with increasing inputs : Mechanisms and controls

Crop residue addition is a way to increase soil organic matter (SOM) level in croplands. However, organic matter input and SOM stocks are not linearly related. Consequently, adding high amounts of residues, such as straw, may increase SOM to only a small extent, and an alternative use of the residues may be justified. The objective of this study was to test how the level and type (above- or belowg

Integrated effect of different N-fertilizer rates and bioslurry application on growth and N-use efficiency of okra (Hibiscus esculentus L.)

Bioslurry obtained from biogas plants has the potential to reduce the use of expensive chemical fertilizers and increase yields. A field experiment was conducted to investigate the growth response and yield production of okra fertilized with various combinations of bioslurry and nitrogen fertilizer. The experiment was planned according to randomized complete block design with 3 replications. Biosl

Role of foliar feeding of micronutrients in yield maximization of cotton in Punjab

Deficiency of micronutrients, particularly of zinc, boron, and iron, in calcareous soils is of great concern. Results indicate a reduction in yield of seed-cotton due to an imbalance of nutrients, particularly micronutrients, on calcareous soils in the last decade. About 90% of Pakistani soils are deficient in micronutrients, particularly zinc, boron, and iron. This paper highlights efforts to ove

To shake or not to shake : Silicone tube approach for incubation studies on CH 4 oxidation in submerged soils

Incubation experiments are the most common approach to measure methane (CH 4 ) oxidation potential in soils from various ecosystems and land-use practices. However, the commonly used headspace CH 4 injection into microcosms and the shaking of the soil slurry during incubation fully removes CH 4 (soil-born) and O 2 (air-born) gradients common in situ, and may also induce various errors and disturb

Introducing strong correlation effects into graphene by gadolinium intercalation

Exotic ordered ground states driven by electronic correlations are expected to be induced in monolayer graphene when doped to the Van Hove singularity. Such doping levels are reached by intercalating Gd in graphene on SiC(0001), resulting in a strong homogeneity and stability. The electronic spectrum now exhibits severe renormalizations. Flat bands develop which are driven by electronic correlatio