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Staten och maten - kan skatter och subventioner rädda liv?

Kostintaget i Sverige följer inte Livsmedelsverkets rekommendationer. I den här studien undersöker vi om skatter och subventioner på livsmedel kan påverka människors matvanor och hälsa. Vi studerar skatter på produkter med hög andel mättade fetter och på produkter med hög andel salt, och hur de är relaterade till dödsfall från kostrelaterade sjukdomar. Vi undersöker även i vilken utsträckning subv

A decade of maize yield gap studies in sub-Saharan Africa: how are farm-level factors considered?

The study of yield gaps has become more complex, prompting the use of varied approaches to measure yields and a wider range of factors to explain these gaps. In the Global North, the focus is on precision farming, whereas in sub-Saharan Africa (SSA), a broader perspective is necessary due to pronounced variability in farmland conditions. While biogeophysical and management factors have been tradit

Interface reduction technique for Enhanced Craig-Bampton method

Substructure coupling and model order reduction using Component Mode Synthesis (CMS) have, over recent years, gained considerable attention in the vibroacoustic analysis of complex structures. In the CMS methodology, the interior dynamics of each subcomponent in a substructured system are represented by a truncated set of normal modes within the lower frequency range, while all physical degrees of

A Fecal Metabolite Signature of Impaired Fasting Glucose : Results From Two Independent Population-Based Cohorts

Prediabetes is a metabolic condition associated with gut mi-crobiome composition, although mechanisms remain elu-sive. We searched for fecal metabolites, a readout of gut microbiome function, associated with impaired fasting glucose (IFG) in 142 individuals with IFG and 1,105 healthy individuals from the UK Adult Twin Registry (TwinsUK). We used the Cooperative Health Research in the Region of Aug

Dose-response analysis of protracted absorbed organ dose and site-specific cancer incidence in Sweden after the Chernobyl nuclear power plant accident

Background: Adult males in Sweden exhibit an increased risk of cancer associated with an increased absorbed dose to the colon from the Chernobyl accident. Methods: A closed cohort, with information on hunter status, included all individuals living in northern Sweden in 1986. Complete annual information on exposure to 137Cs at the dwelling coordinate was available for a total of 2,104,101 individua

Traceable calibration with 177Lu and comparison of activity meters at hospitals in Norway and Sweden

Introduction: The activity meter is used to determine the activity of delivered radiopharmaceuticals, administered activity to patients and reference activity when gamma-cameras are calibrated prior to imaged-based dosimetry. The aim is to describe a procedure for cross-calibration of activity meters at different clinical sites, and report on 177Lu activity results when using factory-set calibrati

Multireference Protonation Energetics of a Dimeric Model of Nitrogenase Iron-Sulfur Clusters

Characterizing the electronic structure of the iron-sulfur clusters in nitrogenase is necessary to understand their role in the nitrogen fixation process. One challenging task is to determine the protonation state of the intermediates in the nitrogen fixing cycle. Here, we use a dimeric iron-sulfur model to study relative energies of protonation at C, S, or Fe. Using a composite method based on co

Multiplicity of grain boundary structures and related energy variations

Ideal minimum-energy grain boundary (GB) structures are usually the only ones considered when characterizing GBs. This limited perspective provides an incomplete view of the possible structural variability of GBs. In the present study, phase field crystal (PFC) simulations are employed in a systematic search of GB states based on -surface sampling, demonstrating PFC to be a capable tool for this p

Different antibiotic treatments for group A streptococcal pharyngitis

Background: Antibiotics provide only modest benefit in treating sore throat, although their effectiveness increases in people with positive throat swabs for group A beta-haemolytic streptococci (GABHS). It is unclear which antibiotic is the best choice if antibiotics are indicated. This is an update of a review first published in 2010, and updated in 2013, 2016, and 2021. Objectives: To assess the

Broken bodies, places and objects : New perspectives on fragmentation in archaeology

Broken Bodies, Places and Objects demonstrates the breadth of fragmentation and fragment use in prehistory and history and provides an up-to-date insight into current archaeological thinking around the topic. A seal broken and shared by two trade parties, dog jaws accompanying the dead in Mesolithic burials, fragments of ancient warships commodified as souvenirs, parts of an ancient dynastic thron

ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition

High-risk neuroblastoma (NB) is a significant clinical challenge. MYCN and Anaplastic Lymphoma Kinase (ALK), which are often involved in high-risk NB, lead to increased replication stress in cancer cells, suggesting therapeutic strategies. We previously identified an ATR (ataxia telangiectasia and Rad3-related)/ALK inhibitor (ATRi/ALKi) combination as such a strategy in two independent genetically

Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the single-cell fecal parasitome in children with celiac disease autoimmunity : a randomized, double-blind placebo-controlled clinical trial

BACKGROUND: Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 positively affect the fecal bacteriome in children with celiac disease autoimmunity after 6 months of supplementation. The aim of the present investigation was to study the effects of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2 on the single-cell parasitome, with a primary focus

Proteomic Determinants of Variation in Cholesterol Efflux : Observations from the Dallas Heart Study

High-density lipoproteins (HDLs) are promising targets for predicting and treating atherosclerotic cardiovascular disease (ASCVD), as they mediate removal of excess cholesterol from lipid-laden macrophages that accumulate in the vasculature. This functional property of HDLs, termed cholesterol efflux capacity (CEC), is inversely associated with ASCVD. HDLs are compositionally diverse, associating

Taxonomical lives : The making of social divisions in the Swedish press during the golden age of social democracy, 1945–76

This article investigates the media lives of a particular class taxonomy in the Swedish press from 1945 to 1976. Invented by the Central Bureau of Statistics in 1911, the ‘social group division’ system was abandoned in the early post-war period. Around the same time, however, it gained popularity in Swedish culture and political debate. While earlier research has noted that such bureaucratic class

Interferometric quantum control (IQC) by fs/ns rotational coherent anti-Stokes Raman spectroscopy (RCARS)

A new rotational coherent anti-Stokes Raman spectroscopy (RCARS) concept based on interferometric quantum control (IQC) is demonstrated. Two wavepackets originating from pure rotational states are created by a femtosecond stimulated rotational Raman interaction. The two Raman responses are instantly probed by a single-mode ns pulse generating two interfering RCARS polarizations. The resulting sign

DETERRENCE BY DENIAL AND RESILIENCE BUILDING

Deterrence and resilience are intimately connected. Deterrence is about understanding threats and using levers that might force an adversary to reconsider their objectives and actions against you. Resilience is about understanding yourself and the measures you can take to become a less attractive target, or to bounce back more quickly from a setback. This combination of deterrence and resilience h