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Standardization proposal of soft tissue artefact description for data sharing in human motion measurements

Soft tissue artefact (STA) represents one of the main obstacles for obtaining accurate and reliable skeletal kinematics from motion capture. Many studies have addressed this issue, yet there is no consensus on the best available bone pose estimator and the expected errors associated with relevant results. Furthermore, results obtained by different authors are difficult to compare due to the high v

Validation of knee joint models - An in vivo study

The effect of modeling the knee as a simple spherical or revolute joint during gait, cutting and hopping were evaluated. The results indicate that, even during gait, a revolute joint may be too restrictive in its representation of the knee, with flexion/extension errors as high as 9.4°. By imposing the spherical joint, joint angles showed consistent and strong correlations with the true joint angl

Predicting post-operative functional ability from pre-operative measures in ACL-injured individuals

Purpose: This study aimed to quantify the relationship between objective and subjective measures of functional ability and determine if measures in the deficient (ACLd) state were correlated to, and capable of predicting a patient's objective and subjective measures in the reconstructed (ACLr) state. Methods: Twenty ACL-injured participants completed hop and side cut movements prior to and 10 mont

Use of muscle synergies and wavelet transforms to identify fatigue during squatting

The objective of this study was to supplement continuous wavelet transforms with muscle synergies in a fatigue analysis to better describe the combination of decreased firing frequency and altered activation profiles during dynamic muscle contractions. Nine healthy young individuals completed the dynamic tasks before and after they squatted with a standard Olympic bar until complete exhaustion. El

Transcriptional intra-tumour heterogeneity predicted by deep learning in routine breast histopathology slides provides independent prognostic information

Background: Intra-tumour heterogeneity (ITH) causes diagnostic challenges and increases the risk for disease recurrence. Quantification of ITH is challenging and has not been demonstrated in large studies. It has previously been shown that deep learning can enable spatially resolved prediction of molecular phenotypes from digital histopathology whole slide images (WSIs). Here we propose a novel me

Förändring pågår! Förslag på förändringsarbete kring kön och könsidentitet i skolan - Bilaga 2

Att vara trans på olika sätt är ingen nödsituation och behöver inte vara dramatiskt. I stället för att enbart reagera i stunden kan politiker, rektorer, lärare, kuratorer, skolsköterskor och andra vuxna skapa en skola där färre spontana lösningar krävs eftersom det finns ett genomtänkt pedagogiskt och administrativt arbete, det som kallas ”whole-of-school approach” (Bartholomaeus & Riggs, 2017Being trans in different ways is not an emergency and does not have to be dramatic. Instead of reacting only in the moment, politicians, principals, teachers, counselors, nurses and other adults can create a school where fewer spontaneous solutions are needed because there is well thought-out pedagogical and administrative work, what is called the 'whole-of-school approach' (Bartholomaeus & Ri

Hygiene may attenuate selection for antibiotic resistance by changing microbial community structure

Good hygiene, in both health care and the community, is central to containing the rise of antibiotic resistance, as well as to infection control more generally. But despite the well-known importance, the ecological mechanisms by which hygiene (or other transmission control measures) affect the evolution of resistance remain to be elucidated. Using metacommunity ecology theory, we here propose that

Efficient Encapsulation and Controlled Release of N,N-Diethyl-3-methylbenzamide (DEET) from Oil-in-Water Emulsions Stabilized by Cationic Nanocellulose and Silica Nanoparticles

Oil-in-water emulsions containing N,N-diethyl-3-methylbenzamide (DEET) were developed aiming to extend the sustained release of the active compound, by using two oppositely charged nanomaterials, namely silica nanoparticles (SiNP) and cationic cellulose nanofibrils (CCNF), as stabilizers, and a mixture of food-grade nonionic surfactants to avoid precipitation by electrostatic aggregation. The form

Role of the Deep Eutectic Solvent Reline in the Synthesis of Gold Nanoparticles

This work presents a mechanistic understanding of the synthesis of small (<3 nm) gold nanoparticles in a nontoxic, eco-friendly, and biodegradable eutectic mixture of choline chloride and urea (reline) without the addition of external reducing or stabilization agents. Reline acts as a reducing agent by releasing ammonia (via urea hydrolysis), forming gold nanoparticles even at trace ammonia concen

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En åpen og opplyst offentlig samtale er en forutsetning for et velfungerende demokrati. Dette idealet fordrer at borgere i stor grad tolererer meningsmotstandere fremfor å utvikle fiendtlige holdninger til dem man er uenig med. En rekke studier fra USA har imidlertid vist at borgere i økende grad er fiendtlig innstilt til velgere de er politisk uenig med (Iyengar et al., 2019). Dette fenomenet er

An empirically based model of software prototyping : a mapping study and a multi-case study

Context: Prototyping is an established practice within product and user interface design that is also used as a requirements engineering (RE) practice within agile development. Even so, there is a lack of theory on prototyping.Aims: Our main research objective is to support practitioners in improving on their prototyping practices.Method: We have designed a model that describes key aspects of the

Software selection in large-scale software engineering: A model and criteria based on interactive rapid reviews

Context: Software selection in large-scale software development continues to be ad hoc and ill-structured. Previous proposals for software component selection tend to be technology-specific and/or do not consider business or ecosystem concerns.Objective: Our main aim is to develop an industrially relevant technology-agnostic method that can support practitioners in making informed decisions when s

Russia's Policy towards Donbas Since 2014 : The Nation-Building Process and Its Ideology

This study examines the ideology of the nation-building process in the so-called Donetsk and Luhansk People's Republics. The key features of this process are uncovered through a discourse analysis of school textbooks published in the People's Republics and in Transnistria, and of the 'Russian Donbas' ideology. This is compared to the history and interpretations of the concept of 'Novorossiya'. Thi

Why do people believe in conspiracy theories?

Conspiracy theories fomented by political division and a global pandemic have gained traction in the public consciousness in the last couple of years. For some people these ideas are just fun and entertaining, but for others their interest in them becomes much more consuming. Why do people become involved in this kind of conspiratorial thinking? That’s the question that LSE iQ tackles in this mont

Hydroxide Conducting Membranes with Quaternary Ammonium Cations Tethered to Poly(arylene alkylene)s via Flexible Phenylpropyl Spacers

Durable and high-performing anion exchange membranes (AEMs) are central components in alkaline water electrolyzers and fuel cells. Here, we have pursued a synthetic strategy where heteroatom-free polymer backbones are functionalized with alkali-stable dimethyl piperidinium (DMP) cations via flexible spacers. We achieved this design by synthesizing a trifluorobenzophenone monomer carrying a piperid