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Three naturally occurring isomers of the disaccharideO-α-D-mannosyl-D-mannoside were synthesized by reversing the hydrolytic activity of jack bean α-mannosidase at 75°C in a very high concentration of mannose. Higher oligosaccharides were also obtained at the later stages of the reaction. The maximum total yield of disaccharides was 37% (w/w) based on the total amount of saccharides.
Anmeldelse af Senseis Mappe af Hiromi Kawakami
BackgroundThere is a growing body of evidence indicating that second degree tears cause both short-, and long-term consequences. Very few preventative measures have been found to reduce the incidence of these tears.ObjectiveTo investigate if the use of a perineal protection device during vaginal birth reduces severe perineal tearing (≥grade 2 tear) in primiparous women compared to routine manual p
The disaccharide 6-O-β-d-galactopyranosyl-2-acetamido-2-deoxy-d-galactose has been synthesized by transfer of the β-d-galactopyranosyl residue from lactose to 2-acetamido-2-deoxy-d-galactose utilizing the transferase activity of β-galactosidase from . To make the enzyme reusable, it was applied in an immobilized form covalently bound to Sepharose CL-4B. The yield of the disaccharide was about 20%,
A crucial aspect of adding an economical and environmental dimension to the upgrading of bio-oils is to develop catalysts with enhanced and prolonged activity. In the present study, the effect of doping δ-alumina (Al2O3) with oxides of cerium (Ce) and lanthanum (La) before thermal treatment was investigated. The performance of such an Al2O3-supported nickel-molybdenum (Ni-Mo) catalyst was evaluate
Affinity precipitation, a novel technique closely related to immunoprecipitation and affinity chromatography, has been evaluated in systems comprised of dehydrogenases and a bifunctional NAD derivative, Bis-NAD. Lactate dehydrogenase and glutamate dehydrogenase were easily precipitated whereas yeast alcohol dehydrogenase required the presence of salt to enhance the affinity precipitation. Liver al
Aims/hypothesis: Regulatory factor X 6 (RFX6) is crucial for pancreatic endocrine development and differentiation. The RFX6 variant p.His293LeufsTer7 is significantly enriched in the Finnish population, with almost 1:250 individuals as a carrier. Importantly, the FinnGen study indicates a high predisposition for heterozygous carriers to develop type 2 and gestational diabetes. However, the precise
The complement system is a proteolytic cascade triggered by pathogen and danger-associated molecular patterns, with resultant outcomes of inflammation, cellular activation, and opsonization of material for removal by phagocytosis. While first discovered as an activity in serum, it is now recognized that complement components play important roles at local and individual cell-intrinsic levels. In pa
Decisions made by millions of refugees about where to go, how to make a living and how to secure a future are fundamental drivers of secondary movements. While a substantial body of literature addresses factors contributing to migrants’ decision-making, a comprehensive understanding of the central role of refugees in secondary mobility decision-making, including agency and strategies employed, rem
Purpose: Fluid-structure interaction (FSI) models are more commonly applied in medical research as computational power is increasing. However, understanding the accuracy of FSI models is crucial, especially in the context of heart valve disease in patient-specific models. Therefore, this study aimed to create a multi-modal benchmarking data set for cardiac-inspired FSI models, based on clinically
Personer med synnedsättningar behöver ljushetskontraster för att varnas, för att få ledning och för att hitta. Kunskapen är emellertid dålig vad gäller utformningsdetaljer. Denna studie skall ligga till grund för förbättring av råden om utformning för bättre orienteringsmöjligheter för personer med synnedsättningar bl.a. vid revidering av Vägverkets och Svenska Kommunförbundets handbok Vägars och
För att personer som är blinda ska kunna orientera sig i den byggda miljön behövs sammanhängande ledstråk som går att följa från start- till målpunkt. Rapporten redovisar en studie av hur ett sammanhängande ledstråk fungerar för personer som är blinda. Ledstråken består av naturliga och konstgjorda ledytor och varningsytor och valytor. Studien kommer att ligga till grund för förbättring av kraven
Trafikverket har ansvar för att förverkliga den beslutade funktionshinderspolitiken, som regleras i regeringsuppdrag och i en särskild förordning, SFS 2014:135. Trafikverket ska vara ett föredöme när det gäller tillgänglighet för personer med funktionsnedsättning, och bidra till allas delaktighet i samhället. Syftet med den föreliggande kunskapssammanställningen är att samla den kunskap som finns
Progressive myoclonus ataxia (PMA) is a rare clinical syndrome characterized by the presence of progressive myoclonus and ataxia, and can be accompanied by mild cognitive impairment and infrequent epileptic seizures. This is the first study to describe the natural history of PMA and identify clinical, electrophysiological, and genetic features explaining the variability in disease progression. A D
