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It has been demonstrated that apolipoprotein M (apoM), a recently discovered HDL apolipoprotein, has antiatherosclerotic properties, which may be mediated by the enhancement of reversed cholesterol transportation and/or hepatic cholesterol catabolism. The detailed mechanisms are unknown yet. Liver X receptor (LXR) belongs to the nuclear receptor superfamily and is a ligand-activated transcription
This paper concerns the development of innovative composite floor systems, comprising timber beams and prefabricated concrete slabs. For the development of this new system, two properties were regarded as vital, as follows: (1) good stiffness, and (2) a high degree of prefabrication. Shear connection systems installed using completely dry processes were used. Innovative and very efficient material
Abstract: The adoption of innovation is a multifaceted and dynamic phenomenon. It occurs as a result of the interplay between structural influences and agents’ activities. Although existing studies on innovation have recognised the importance of theories that link the structure, the macro level, and agency, the micro level, in explaining changes over time, few theoretical accounts support the inte
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and the total number of AF patients is constantly increasing. The mechanisms leading to and sustaining AF are not completely understood yet. Heterogeneities in atrial electrophysiology seem to play an important role in this context. Although some heterogeneities have been used in in-silico human atrial modeling studies, they have not
Popular Abstract in Swedish Det är en utmaning att behandla patienter med allvarliga infektioner eftersom immunförsvaret reagerar olika på olika mikroorganismer. Immunförsvarets reaktion har i sin tur en stor betydelse för symtombild, kliniska fynd och prognos. Vid blodförgiftning (sepsis) förändras dessutom sannolikt immunsvaret under det kliniska förloppet. Man tror att det inledningsvis vid sepInfectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. There is often a rapid onset, which may constitute a diagnostic and therapeutic challenge, whereas in other cases an extensive investigation over a long time period can fail to ident
Background: Although widely used, the validity and reliability of the Clavien classification of postoperative complications have not been tested in urologic procedures, such as percutaneous nephrolithotomy (PCNL). Objective: To validate the Clavien score and categorise complications of PCNL. Design, setting, and participants: Data for 528 patients with complications after PCNL were used to create
Previous research on victimhood during and after the Bosnian war has emphasized the importance of narratives but has not focused on narratives about victimhood or analyzed post-war interviews as a competition for victimhood. This article tries to fill this gap using stories told by survivors of the Bosnian war during the 1990s. In this analysis of the retold experiences of 27 survivors of the war
Climate warming is expected to alter hydropower generation in California through affecting the annual stream-flow regimes and reducing snowpack. On the other hand, increased temperatures are expected to increase hydropower demand for cooling in warm periods while decreasing demand for heating in winter, subsequently altering the annual hydropower pricing patterns. The resulting variations in hydro
Book review
Virtual meetings (VMs), i.e. audio-, video- and web-conferencing, could be used to decrease the environmental impact of business activities, reduce travel costs, increase business mobility and collaboration, and improve flexibility and productivity of the employees. Swedish national policy supports the implementation of VMs as one of the solutions towards low carbon infrastructure and sustainable
The aim of this paper is to study rate-dependent switching in ferroelastic materials. More specifically, a micro-mechanically motivated model is embedded into an iterative three-dimensional and electromechanically coupled finite element framework. An established energy-based criterion serves for the initiation of domain switching processes as based on reduction in (local) Gibbs free energy. Subseq
Measurements of the midrapidity transverse-energy distribution, dE(T)/d eta, are presented for p + p, d+Au, and Au+Au collisions atv root s(NN) = 200 GeV and additionally for Au+Au collisions atv root s(NN) = 62.4 and 130 GeV. The dE(T)/d eta distributions are first compared with the number of nucleon participants N-part, number of binary collisions N-coll, and number of constituent-quark particip
The association between hydrophobically modified polyethylene glycol, HM-PEG, and non-ionic vesicles of tetraethylene glycol monododecyl ether, C12E4, was investigated. HM-PEG is in a triblock form, with an alkyl chain attached to each hydrophilic polymer-end. Such polymer structure is denoted as telechelic. The vesicle average radius was measured by self-diffusion measurements. The system exhibit
Objective: To describe dietary carbohydrate intakes and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: Between 1995 and 2000, 36 034 subjects, aged between 35-74 years, were administered a standardized, 24-h dietary recall using a computerized interview software programme (EPIC-SOFT). Inta
The mechanisms of neuronal cell death are still only poorly understood, which has hindered the advancement of therapies for many currently untreatable neurodegenerative diseases. This calls for the development of new methods which reveal critical molecular mechanisms of the celldeath machinery with both high sensitivity and cellular resolution. Using animal models for hereditary neurodegeneration
Objectives To determine the agreement between ultrasound and histological examination of the cervix in patients with early stage cervical cancer with regard to tumor size and local extent of the disease. Methods Eighteen patients with histologically proven cervical cancer Stage IB1-IIA according to traditional clinical staging (FIGO 1988) who were scheduled for radical surgery underwent a standard
