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Objective: Citrate is widely used in dialysis, either as an acid in dialysis fluids or as a regional anticoagulant. In both cases, the concentration of citrate in the plasma of the patients will increase above physiological levels, up to 5-foldes in some cases. The aim of this study was to investigate the effect of citrate on the transcriptional level, as well as on the metabolic level and elucida
